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British Journal of Experimental Pathology logoLink to British Journal of Experimental Pathology
. 1980 Jun;61(3):310–314.

Focal mesangial proliferative glomerulonephritis in the rat caused by Habu venom: the effect of antiplatelet agents.

V Cattell, A Mehotra
PMCID: PMC2041587  PMID: 7000132

Abstract

The effects of the antiplatelet agents aspirin (ASA), dipyridamole (DP) and prostacyclin (PGI2) on glomerulonephritis following Habu snake venom have been investigated. ASA greatly increases glomerular damage and PGI2 inhibits glomerular damage. DP suppresses glomerular proliferation. The results extend previous studies on platelet activity in this model and provide evidence that (1) glomerular injury involves a platelet/endothelial reaction and (2) glomerular proliferation is affected by an antiplatelet drug.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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