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. 1994 Feb;176(4):1192–1196. doi: 10.1128/jb.176.4.1192-1196.1994

One-ended insertion of IS911.

P Polard 1, L Seroude 1, O Fayet 1, M F Prère 1, M Chandler 1
PMCID: PMC205174  PMID: 8106332

Abstract

An apparently nonreplicative integration reaction mediated by the insertion sequence IS911 has been analyzed. It is shown to involve the right-end inverted repeat (IRR) of the element and sequences in the flanking vector DNA. The flanking sequences appear to behave as a surrogate IS911 end, since integration is greatly reduced when limited similarities with IRR are eliminated by site-directed mutagenesis. Data are presented which suggest that the activity of the IRR junction results from the proximity of the transposase gene and may therefore reflect preferential transposase recognition of IRR in cis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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