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. 1994 Mar;176(6):1801–1804. doi: 10.1128/jb.176.6.1801-1804.1994

Analysis of type II polyketide beta-ketoacyl synthase specificity in Streptomyces coelicolor A3(2) by trans complementation of actinorhodin synthase mutants.

E S Kim 1, D A Hopwood 1, D H Sherman 1
PMCID: PMC205275  PMID: 8132481

Abstract

Complementation of defined actinorhodin beta-ketoacyl synthase (KS) mutants by various other KS genes suggested that the ORF1-encoded KS may be relatively generalized in function, whereas the ORF2-encoded KS component may provide specificity in polyketide chain construction. Evidence for differential temporal-spatial expression of the actinorhodin and spore pigment KSs in Streptomyces coelicolor was obtained.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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