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. 1992 Jan;174(2):623–626. doi: 10.1128/jb.174.2.623-626.1992

Molecular characterization of mutations affecting expression level and growth rate-dependent regulation of the Escherichia coli zwf gene.

D L Rowley 1, W P Fawcett 1, R E Wolf Jr 1
PMCID: PMC205758  PMID: 1729252

Abstract

We characterized three cis dominant mutations which elevate glucose 6-phosphate dehydrogenase level. Growth rate-dependent regulation and oxidative stress control of enzyme level were altered by the mutations. DNA sequencing and transcript mapping showed that the "up" mutations created new promoters whose hyperactive expression overrides the normal regulation of the native promoter.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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