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British Journal of Cancer logoLink to British Journal of Cancer
. 1998 Aug;78(3):419–420. doi: 10.1038/bjc.1998.509

Incidence rates of classical Kaposi's sarcoma and multiple myeloma do not correlate.

H Hjalgrim 1, M Frisch 1, M Melbye 1
PMCID: PMC2063027  PMID: 9703293

Abstract

We compared population-based incidence rates for classical Kaposi's sarcoma and multiple myeloma. Neither for men (Spearman's rank correlation coefficient (r) = 0.01, P = 0.97, 13 pairs) nor for women (r = 0.24, P = 0.42, 13 pairs) did the incidences of the two conditions correlate. This absence of correlation does not support the hypothesis that Kaposi's sarcoma and multiple myeloma share a common aetiology, such as HHV-8.

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Selected References

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  1. Biggar R. J., Curtis R. E., Cote T. R., Rabkin C. S., Melbye M. Risk of other cancers following Kaposi's sarcoma: relation to acquired immunodeficiency syndrome. Am J Epidemiol. 1994 Feb 15;139(4):362–368. doi: 10.1093/oxfordjournals.aje.a117008. [DOI] [PubMed] [Google Scholar]
  2. Biggar R. J., Horm J., Fraumeni J. F., Jr, Greene M. H., Goedert J. J. Incidence of Kaposi's sarcoma and mycosis fungoides in the United States including Puerto Rico, 1973-81. J Natl Cancer Inst. 1984 Jul;73(1):89–94. [PubMed] [Google Scholar]
  3. Brousset P., Meggetto F., Attal M., Delsol G. Kaposi's sarcoma-associated herpesvirus infection and multiple myeloma. Science. 1997 Dec 12;278(5345):1972–1973. [PubMed] [Google Scholar]
  4. Cesarman E., Chang Y., Moore P. S., Said J. W., Knowles D. M. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. N Engl J Med. 1995 May 4;332(18):1186–1191. doi: 10.1056/NEJM199505043321802. [DOI] [PubMed] [Google Scholar]
  5. Chang Y., Cesarman E., Pessin M. S., Lee F., Culpepper J., Knowles D. M., Moore P. S. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science. 1994 Dec 16;266(5192):1865–1869. doi: 10.1126/science.7997879. [DOI] [PubMed] [Google Scholar]
  6. Dupin N., Gorin I., Deleuze J., Agut H., Huraux J. M., Escande J. P. Herpes-like DNA sequences, AIDS-related tumors, and Castleman's disease. N Engl J Med. 1995 Sep 21;333(12):798–799. [PubMed] [Google Scholar]
  7. Gao S. J., Kingsley L., Li M., Zheng W., Parravicini C., Ziegler J., Newton R., Rinaldo C. R., Saah A., Phair J. KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nat Med. 1996 Aug;2(8):925–928. doi: 10.1038/nm0896-925. [DOI] [PubMed] [Google Scholar]
  8. Geddes M., Franceschi S., Barchielli A., Falcini F., Carli S., Cocconi G., Conti E., Crosignani P., Gafà L., Giarelli L. Kaposi's sarcoma in Italy before and after the AIDS epidemic. Br J Cancer. 1994 Feb;69(2):333–336. doi: 10.1038/bjc.1994.60. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Grulich A. E., Beral V., Swerdlow A. J. Kaposi's sarcoma in England and Wales before the AIDS epidemic. Br J Cancer. 1992 Dec;66(6):1135–1137. doi: 10.1038/bjc.1992.423. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Hjalgrim H., Frisch M., Pukkala E., Tulinius H., Ekbom A., Dictor M., Langmark F., Hardarson S., Melbye M. Risk of second cancers in classical Kaposi's sarcoma. Int J Cancer. 1997 Dec 10;73(6):840–843. doi: 10.1002/(sici)1097-0215(19971210)73:6<840::aid-ijc13>3.0.co;2-8. [DOI] [PubMed] [Google Scholar]
  11. Hjalgrim H., Melbye M., Pukkala E., Langmark F., Frisch M., Dictor M., Ekbom A. Epidemiology of Kaposi's sarcoma in the Nordic countries before the AIDS epidemic. Br J Cancer. 1996 Nov;74(9):1499–1502. doi: 10.1038/bjc.1996.572. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Hjalgrim H., Tulinius H., Dalberg J., Hardarson S., Frisch M., Melbye M. High incidence of classical Kaposi's sarcoma in Iceland and the Faroe Islands. Br J Cancer. 1998 Apr;77(7):1190–1193. doi: 10.1038/bjc.1998.198. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Kaldor J. M., Coates M., Vettom L., Taylor R. Epidemiological characteristics of Kaposi's sarcoma prior to the AIDS epidemic. Br J Cancer. 1994 Oct;70(4):674–676. doi: 10.1038/bjc.1994.370. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Levi F., Franceschi S., La Vecchia C. Kaposi's sarcoma in the Swiss Canton of Vaud, 1974-1990. Eur J Cancer. 1993;29A(13):1918–1919. doi: 10.1016/0959-8049(93)90562-t. [DOI] [PubMed] [Google Scholar]
  15. Luppi M., Barozzi P., Marasca R., Ferrari M. G., Torelli G. Human herpesvirus 8 strain variability in clinical conditions other than Kaposi's sarcoma. J Virol. 1997 Oct;71(10):8082–8083. doi: 10.1128/jvi.71.10.8082-8083.1997. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. MacKenzie J., Sheldon J., Morgan G., Cook G., Schulz T. F., Jarrett R. F. HHV-8 and multiple myeloma in the UK. Lancet. 1997 Oct 18;350(9085):1144–1145. doi: 10.1016/s0140-6736(05)63792-0. [DOI] [PubMed] [Google Scholar]
  17. Marcelin A. G., Dupin N., Bouscary D., Bossi P., Cacoub P., Ravaud P., Calvez V. HHV-8 and multiple myeloma in France. Lancet. 1997 Oct 18;350(9085):1144–1144. doi: 10.1016/S0140-6736(05)63791-9. [DOI] [PubMed] [Google Scholar]
  18. Masood R., Zheng T., Tupule A., Arora N., Chatlynne L., Handy M., Whitman J., Jr Kaposi's sarcoma-associated herpesvirus infection and multiple myeloma. Science. 1997 Dec 12;278(5345):1970–1973. [PubMed] [Google Scholar]
  19. Parravicini C., Lauri E., Baldini L., Neri A., Poli F., Sirchia G., Moroni M., Galli M., Corbellino M. Kaposi's sarcoma-associated herpesvirus infection and multiple myeloma. Science. 1997 Dec 12;278(5345):1969–1973. doi: 10.1126/science.278.5345.1969. [DOI] [PubMed] [Google Scholar]
  20. Pastore C., Gloghini A., Volpe G., Nomdedeu J., Leonardo E., Mazza U., Saglio G., Carbone A., Gaidano G. Distribution of Kaposi's sarcoma herpesvirus sequences among lymphoid malignancies in Italy and Spain. Br J Haematol. 1995 Dec;91(4):918–920. doi: 10.1111/j.1365-2141.1995.tb05410.x. [DOI] [PubMed] [Google Scholar]
  21. Rettig M. B., Ma H. J., Vescio R. A., Põld M., Schiller G., Belson D., Savage A., Nishikubo C., Wu C., Fraser J. Kaposi's sarcoma-associated herpesvirus infection of bone marrow dendritic cells from multiple myeloma patients. Science. 1997 Jun 20;276(5320):1851–1854. doi: 10.1126/science.276.5320.1851. [DOI] [PubMed] [Google Scholar]
  22. Said J. W., Rettig M. R., Heppner K., Vescio R. A., Schiller G., Ma H. J., Belson D., Savage A., Shintaku I. P., Koeffler H. P. Localization of Kaposi's sarcoma-associated herpesvirus in bone marrow biopsy samples from patients with multiple myeloma. Blood. 1997 Dec 1;90(11):4278–4282. [PubMed] [Google Scholar]
  23. Simpson G. R., Schulz T. F., Whitby D., Cook P. M., Boshoff C., Rainbow L., Howard M. R., Gao S. J., Bohenzky R. A., Simmonds P. Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. Lancet. 1996 Oct 26;348(9035):1133–1138. doi: 10.1016/S0140-6736(96)07560-5. [DOI] [PubMed] [Google Scholar]
  24. Whitby D., Boshoff C., Luppi M., Torelli G. Kaposi's sarcoma-associated herpesvirus infection and multiple myeloma. Science. 1997 Dec 12;278(5345):1971–1973. [PubMed] [Google Scholar]

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