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. 1993 Oct;175(19):6113–6117. doi: 10.1128/jb.175.19.6113-6117.1993

Processing of lipid-modified prolipoprotein requires energy and sec gene products in vivo.

N Kosic 1, M Sugai 1, C K Fan 1, H C Wu 1
PMCID: PMC206704  PMID: 8407783

Abstract

The kinetics of processing of glyceride-modified prolipoprotein that accumulated in globomycin-treated Escherichia coli has been found to be affected by sec mutations, i.e., secA, secE, secY, secD, and secF, and by metabolic poisons which affect proton motive force (PMF). The effect of sec mutations on processing of glyceride-modified prolipoprotein in vivo was not due to a secondary effect on PMF. Neither a secF mutation nor metabolic poisons affected the processing of previously accumulated proOmpA protein in vivo, suggesting that the requirements for functional sec gene products and PMF are specific to the processing of lipoprotein precursors by signal peptidase II.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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