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British Journal of Experimental Pathology logoLink to British Journal of Experimental Pathology
. 1974 Apr;55(2):164–168.

Radiological Diagnosis of Crocidolite Induced Pleural Mesotheliomata in the Rat

M S F McLachlan, J C Wagner
PMCID: PMC2072523  PMID: 4835804

Abstract

Crocidolite asbestos dust was inoculated intrapleurally in 36 rats. Chest radiographs were obtained up to 120 weeks after inoculation. Radiological and pathological observations were compared. In 3 animals, in which mesotheliomata were suspected radiologically, no evidence of malignancy was observed on histological examination. A radiological diagnosis suggesting probable or definite malignancy was made in all 7 animals with histologically proven mesotheliomata.

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  1. Wagner J. C., Berry G. Mesotheliomas in rats following inoculation with asbestos. Br J Cancer. 1969 Sep;23(3):567–581. doi: 10.1038/bjc.1969.70. [DOI] [PMC free article] [PubMed] [Google Scholar]

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