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. 1988 Jan;170(1):431–435. doi: 10.1128/jb.170.1.431-435.1988

Variation in precursor pool size during the division cycle of Escherichia coli: further evidence for linear cell growth.

H E Kubitschek 1, S R Pai 1
PMCID: PMC210660  PMID: 2447064

Abstract

The magnitudes of several pools of radioactively labeled precursors for RNA and protein synthesis were determined as a function of cell age during the division cycle of Escherichia coli 15 THU. Uracil, histidine, and methionine pools increased from low initial values for cells at birth to maxima during midcycle and then subsided again. These pools were small or nonexistent at the beginning and the end of the cycle, and their average values during the cycle were less than 4% of the total cellular radioactivity. The results are consistent with a linear pattern of growth for cells during the division cycle and provide strong evidence against exponential or bilinear growth of E. coli cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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