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. 1988 Jan;170(1):446–448. doi: 10.1128/jb.170.1.446-448.1988

ATP-liganded form of aspartate transcarbamoylase, the logical regulatory target for allosteric control in divergent bacterial systems.

J R Wild 1, J L Johnson 1, S J Loughrey 1
PMCID: PMC210664  PMID: 3275626

Abstract

In Escherichia coli, the mechanism for regulatory control of aspartate transcarbamoylase is clear; CTP allosterically inhibits catalysis in direct competition with ATP. However, both CTP and ATP may be activators or may have no effect on aspartate transcarbamoylases from other enteric bacteria. A common regulatory logic observed was that the ATP-activated enzymes were rendered less active as the result of competition with CTP, regardless of the independent effects.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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