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. 1987 Jun;169(6):2367–2372. doi: 10.1128/jb.169.6.2367-2372.1987

Photoreactivation in phr mutants of Escherichia coli K-12.

I Husain, A Sancar
PMCID: PMC212064  PMID: 3294788

Abstract

We have investigated the genetics of photoreactivation in Escherichia coli K-12. We found that strains with point mutations or deletions in the phr gene showed a significant residual level of photoreactivation after exposure to large fluences of photoreactivating light. It had been previously proposed that a gene in the gal-att lambda interval is also involved in photoreactivation and that the residual photoreactivating activity might be due to this so-called phrA gene located at this interval. We found that deletions of the gal-att lambda region had no effect on either the rate or the final extent of photoreactivation observed in phr+ cells or phr mutants; however strains carrying the delta (gal-att lambda) deletions displayed increased sensitivity to near-UV radiation.

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Selected References

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