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. 1985 Feb;94(1):23–29. doi: 10.1017/s002217240006109x

Studies on staphylococci from toxic shock syndrome in France, 1981-1983.

A K Melconian, J Fleurette, Y Brun
PMCID: PMC2129396  PMID: 3973379

Abstract

Staphylococci from 22 cases of toxic shock syndrome with onsets between 1981 and March 1983 have been studied. Another four cases were detected by abstract surveillance. Three of these patients died. The case histories show that the syndrome occurs in women during menstruation as well as in males and in children, and is associated with Staphylococcus aureus infections. The production of enterotoxins (A, B, C) and toxic shock toxin by S. aureus isolates from toxic shock syndrome was investigated. Twenty-two of the 23 isolates were found to be toxigenic: 7 produced enterotoxin A, 8 produced enterotoxin B, 3 produced enterotoxin C and 13 produced toxic shock toxin. The latter was found with enterotoxin A in five cases, and with enterotoxins A and B in only one case. Sixty-three percent of 46 S. aureus strains isolated from the vagina of patients with diseases other than toxic shock syndrome produced toxin; eight of these strains produced toxic shock toxin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abadie J. C., Gouet D., Marechaud R., Becq-Giraudon B., Sudre Y. Syndrome de choc toxique staphylococcique à porte d'entrée extragynécologique. Nouv Presse Med. 1981 Dec 19;10(46):3793–3793. [PubMed] [Google Scholar]
  2. Altemeier W. A., Lewis S. A., Schlievert P. M., Bergdoll M. S., Bjornson H. S., Staneck J. L., Crass B. A. Staphylococcus aureus associated with toxic shock syndrome: phage typing and toxin capability testing. Ann Intern Med. 1982 Jun;96(6 Pt 2):978–982. doi: 10.7326/0003-4819-96-6-978. [DOI] [PubMed] [Google Scholar]
  3. Bartlett P., Reingold A. L., Graham D. R., Dan B. B., Selinger D. S., Tank G. W., Wichterman K. A. Toxic shock syndrome associated with surgical wound infections. JAMA. 1982 Mar 12;247(10):1448–1450. [PubMed] [Google Scholar]
  4. Bergdoll M. S., Crass B. A., Reiser R. F., Robbins R. N., Davis J. P. A new staphylococcal enterotoxin, enterotoxin F, associated with toxic-shock-syndrome Staphylococcus aureus isolates. Lancet. 1981 May 9;1(8228):1017–1021. doi: 10.1016/s0140-6736(81)92186-3. [DOI] [PubMed] [Google Scholar]
  5. Bonventre P. F., Weckbach L., Staneck J., Schlievert P. M., Thompson M. Production of staphylococcal enterotoxin F and pyrogenic exotoxin C by Staphylococcus aureus isolates from toxic shock syndrome-associated sources. Infect Immun. 1983 Jun;40(3):1023–1029. doi: 10.1128/iai.40.3.1023-1029.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Clayton A. J., Peacocke J. E., Ewan P. E. Toxic shock syndrome in Canada. Can Med Assoc J. 1982 Apr 1;126(7):776–779. [PMC free article] [PubMed] [Google Scholar]
  7. Davis J. P., Chesney P. J., Wand P. J., LaVenture M. Toxic-shock syndrome: epidemiologic features, recurrence, risk factors, and prevention. N Engl J Med. 1980 Dec 18;303(25):1429–1435. doi: 10.1056/NEJM198012183032501. [DOI] [PubMed] [Google Scholar]
  8. Davis J. P., Osterholm M. T., Helms C. M., Vergeront J. M., Wintermeyer L. A., Forfang J. C., Judy L. A., Rondeau J., Schell W. L. Tri-state toxic-shock syndrome study. II. Clinical and laboratory findings. J Infect Dis. 1982 Apr;145(4):441–448. doi: 10.1093/infdis/145.4.441. [DOI] [PubMed] [Google Scholar]
  9. El Solh N., Bismuth R., Allignet J., Fouace J. M. Résistance à la pristinamycine (ou virginiamycine) des souches de Staphylococcus aureus. Pathol Biol (Paris) 1984 May;32(5):362–368. [PubMed] [Google Scholar]
  10. Granthil C., Dumont J. C., Brun Y. Syndrome de choc toxique à staphylocoque doré groupe II, producteur d'entérotoxine B. Nouv Presse Med. 1982 Jan 9;11(1):54–54. [PubMed] [Google Scholar]
  11. HALLANDER H. O. PRODUCTION OF LARGE QUANTITIES OF ENTEROTOXIN B AND OTHER STAPHYLOCOCCAL TOXINS ON SOLID MEDIA. Acta Pathol Microbiol Scand. 1965;63:299–305. doi: 10.1111/apm.1965.63.2.299. [DOI] [PubMed] [Google Scholar]
  12. Letellier N., Coulomb F., Lebec C., Brunet J. M., Lababidi A., Thery P., Tinel G. Choc toxique staphylococcique. Nouv Presse Med. 1982 Mar 27;11(14):1080–1080. [PubMed] [Google Scholar]
  13. Linnemann C. C., Jr, Staneck J. L., Hornstein S., Barden T. P., Rauh J. L., Bonventre P. F., Buncher C. R., Beiting A. The epidemiology of genital colonization with Staphylococcus aureus. Ann Intern Med. 1982 Jun;96(6 Pt 2):940–944. doi: 10.7326/0003-4819-96-6-940. [DOI] [PubMed] [Google Scholar]
  14. Melconian A. K., Brun Y., Fleurette J. Enterotoxin production, phage typing and serotyping of Staphylococcus aureus strains isolated from clinical materials and food. J Hyg (Lond) 1983 Oct;91(2):235–242. doi: 10.1017/s0022172400060241. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Melconian A. K., Flandrois J. P., Fleurette J. Modified method for production and purification of Staphylococcus aureus enterotoxin B. Appl Environ Microbiol. 1983 Mar;45(3):1140–1143. doi: 10.1128/aem.45.3.1140-1143.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Paris A. L., Herwaldt L. A., Blum D., Schmid G. P., Shands K. N., Broome C. V. Pathologic findings in twelve fatal cases of toxic shock syndrome. Ann Intern Med. 1982 Jun;96(6 Pt 2):852–857. doi: 10.7326/0003-4819-96-6-852. [DOI] [PubMed] [Google Scholar]
  17. Rapin M., D'Enfert J., Cabane J. Le syndrome de choc toxique staphylococcique. 3 observations. Nouv Presse Med. 1981 Jun 13;10(26):2167–2170. [PubMed] [Google Scholar]
  18. Reingold A. L., Hargrett N. T., Dan B. B., Shands K. N., Strickland B. Y., Broome C. V. Nonmenstrual toxic shock syndrome: a review of 130 cases. Ann Intern Med. 1982 Jun;96(6 Pt 2):871–874. doi: 10.7326/0003-4819-96-6-871. [DOI] [PubMed] [Google Scholar]
  19. Reingold A. L., Hargrett N. T., Shands K. N., Dan B. B., Schmid G. P., Strickland B. Y., Broome C. V. Toxic shock syndrome surveillance in the United States, 1980 to 1981. Ann Intern Med. 1982 Jun;96(6 Pt 2):875–880. doi: 10.7326/0003-4819-96-6-875. [DOI] [PubMed] [Google Scholar]
  20. Reiser R. F., Robbins R. N., Khoe G. P., Bergdoll M. S. Purification and some physicochemical properties of toxic-shock toxin. Biochemistry. 1983 Aug 2;22(16):3907–3912. doi: 10.1021/bi00285a028. [DOI] [PubMed] [Google Scholar]
  21. Rouffineau J., Ducroz B., Bauple J. L., Poncin E., Lhuissier D., Becq-Giraudon B. Oedème pulmonaire lésionnel au cours d'un syndrome de choc toxique staphylococcique. Nouv Presse Med. 1982 Feb 27;11(9):676–677. [PubMed] [Google Scholar]
  22. Schlievert P. M., Shands K. N., Dan B. B., Schmid G. P., Nishimura R. D. Identification and characterization of an exotoxin from Staphylococcus aureus associated with toxic-shock syndrome. J Infect Dis. 1981 Apr;143(4):509–516. doi: 10.1093/infdis/143.4.509. [DOI] [PubMed] [Google Scholar]
  23. Shands K. N., Schlech W. F., 3rd, Hargrett N. T., Dan B. B., Schmid G. P., Bennett J. V. Toxic shock syndrome: case-control studies at the Centers for Disease Control. Ann Intern Med. 1982 Jun;96(6 Pt 2):895–898. doi: 10.7326/0003-4819-96-6-895. [DOI] [PubMed] [Google Scholar]
  24. Shands K. N., Schmid G. P., Dan B. B., Blum D., Guidotti R. J., Hargrett N. T., Anderson R. L., Hill D. L., Broome C. V., Band J. D. Toxic-shock syndrome in menstruating women: association with tampon use and Staphylococcus aureus and clinical features in 52 cases. N Engl J Med. 1980 Dec 18;303(25):1436–1442. doi: 10.1056/NEJM198012183032502. [DOI] [PubMed] [Google Scholar]
  25. Todd J., Fishaut M., Kapral F., Welch T. Toxic-shock syndrome associated with phage-group-I Staphylococci. Lancet. 1978 Nov 25;2(8100):1116–1118. doi: 10.1016/s0140-6736(78)92274-2. [DOI] [PubMed] [Google Scholar]
  26. Tofte R. W., Williams D. N. Toxic shock syndrome. Evidence of a broad clinical spectrum. JAMA. 1981 Nov 13;246(19):2163–2167. doi: 10.1001/jama.246.19.2163. [DOI] [PubMed] [Google Scholar]
  27. de Saxe M. J., Wieneke A., de Asavedo J., Arbuthnott J. P. Toxic shock syndrome in Britain. Br Med J (Clin Res Ed) 1982 May 29;284(6329):1641–1642. [PMC free article] [PubMed] [Google Scholar]

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