Skip to main content
PMC home page
The Journal of Hygiene logoLink to The Journal of Hygiene
. 1979 Dec;83(3):531–538. doi: 10.1017/s0022172400026383

The occurrence of plasmids carrying genes for both enterotoxin production and drug resistance in Escherichia coli of human origin.

S M Scotland, R J Gross, T Cheasty, B Rowe
PMCID: PMC2130170  PMID: 390047

Abstract

Twenty-three of 89 enterotoxigenic strains of Escherichia coli were resistant to one or more antimicrobial agents. Eleven strains transferred resistance directly and five transferred resistance after mobilization. In three cases a resistant recipient was enterotoxigenic. One of these strains contained a conjugative plasmid carrying genes for both drug resistance and enterotoxin production. In the two other strains genes for drug resistance and enterotoxin production were carried on separate co-transferable plasmids.

Full text

PDF
535

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson E. S., Threlfall E. J., Carr J. M., McConnell M. M., Smith H. R. Clonal distribution of resistance plasmid-carrying Salmonella typhimurium, mainly in the Middle East. J Hyg (Lond) 1977 Dec;79(3):425–448. doi: 10.1017/s0022172400053286. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Dean A. G., Ching Y. C., Williams R. G., Harden L. B. Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu. J Infect Dis. 1972 Apr;125(4):407–411. doi: 10.1093/infdis/125.4.407. [DOI] [PubMed] [Google Scholar]
  3. Donta S. T., Moon H. W., Whipp S. C. Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture. Science. 1974 Jan 25;183(4122):334–336. doi: 10.1126/science.183.4122.334. [DOI] [PubMed] [Google Scholar]
  4. Dupont H. L., West H., Evans D. G., Olarte J., Evans D. J., Jr Antimicrobial susceptibility of enterotoxigenic Escherichia coli. J Antimicrob Chemother. 1978 Jan;4(1):100–102. doi: 10.1093/jac/4.1.100. [DOI] [PubMed] [Google Scholar]
  5. Echeverria P., Verhaert L., Ulyangco C. V., Komalarini S., Ho M. T., Orskov F., Orskov I. Antimicrobial resistance and enterotoxin production among isolates of Escherichia coli in the Far East. Lancet. 1978 Sep 16;2(8090):589–592. doi: 10.1016/s0140-6736(78)92820-9. [DOI] [PubMed] [Google Scholar]
  6. FREDERICQ P. Colicins. Annu Rev Microbiol. 1957;11:7–22. doi: 10.1146/annurev.mi.11.100157.000255. [DOI] [PubMed] [Google Scholar]
  7. Grindley J. N., Anderson E. S. I-like resistance factors with the fi+ character. Genet Res. 1971 Jun;17(3):267–271. doi: 10.1017/s0016672300012295. [DOI] [PubMed] [Google Scholar]
  8. Grindley N. D., Humphreys G. O., Anderson E. S. Molecular studies of R factor compatibility groups. J Bacteriol. 1973 Jul;115(1):387–398. doi: 10.1128/jb.115.1.387-398.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Guerrant R. L., Brunton L. L., Schnaitman T. C., Rebhun L. I., Gilman A. G. Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli. Infect Immun. 1974 Aug;10(2):320–327. doi: 10.1128/iai.10.2.320-327.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Gyles C. L., Palchaudhuri S., Maas W. K. Naturally occurring plasmid carrying genes for enterotoxin production and drug resistance. Science. 1977 Oct 14;198(4313):198–199. doi: 10.1126/science.333581. [DOI] [PubMed] [Google Scholar]
  11. Gyles C., So M., Falkow S. The enterotoxin plasmids of Escherichia coli. J Infect Dis. 1974 Jul;130(1):40–49. doi: 10.1093/infdis/130.1.40. [DOI] [PubMed] [Google Scholar]
  12. Haltalin K. C., Markley A. H., Woodman E. Agar plate dilution method for routine antibiotic susceptibility testing in a hospital laboratory. Am J Clin Pathol. 1973 Sep;60(3):384–394. doi: 10.1093/ajcp/60.3.384. [DOI] [PubMed] [Google Scholar]
  13. McConnell M. M., Willshaw G. A., Smith H. R., Scotland S. M., Rowe B. Transposition of ampicillin resistance to an enterotoxin plasmid in an Escherichia coli strain of human origin. J Bacteriol. 1979 Aug;139(2):346–355. doi: 10.1128/jb.139.2.346-355.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Merson M. H., Morris G. K., Sack D. A., Wells J. G., Feeley J. C., Sack R. B., Creech W. B., Kapikian A. Z., Gangarosa E. J. Travelers' diarrhea in Mexico. A prospective study of physicians and family members attending a congress. N Engl J Med. 1976 Jun 10;294(24):1299–1305. doi: 10.1056/NEJM197606102942401. [DOI] [PubMed] [Google Scholar]
  15. Meyers J. A., Sanchez D., Elwell L. P., Falkow S. Simple agarose gel electrophoretic method for the identification and characterization of plasmid deoxyribonucleic acid. J Bacteriol. 1976 Sep;127(3):1529–1537. doi: 10.1128/jb.127.3.1529-1537.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Meynell E., Cooke M. Repressor-minus and operator-constitutive de-repressed mutants of F-like R factors: their effect on chromosomal transfer by HfrC. Genet Res. 1969 Dec;14(3):309–313. doi: 10.1017/s0016672300002123. [DOI] [PubMed] [Google Scholar]
  17. Sack D. A., Kaminsky D. C., Sack R. B., Itotia J. N., Arthur R. R., Kapikian A. Z., Orskov F., Orskov I. Prophylactic doxycycline for travelers' diarrhea. Results of a prospective double-blind study of Peace Corps volunteers in Kenya. N Engl J Med. 1978 Apr 6;298(14):758–763. doi: 10.1056/NEJM197804062981402. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Hygiene are provided here courtesy of Cambridge University Press

RESOURCES