Abstract
Pigs exposed to relatively small amounts of virus by intradermal inoculation of the feet or by skin sacrification developed clinical disease. Large amounts of virus were recovered from samples taken from the nose, mouth, pharynx, rectum and the prepuce or vagina during the first week of infection and smaller amounts during the second week. Virus was recovered from the faeces of most animals 16 days after infection and from one animal for 23 days. Pigs in contact with inoculated animals were killed at intervals before the appearance of clinical disease. The distribution and amounts of virus in various tissues indicated that infection has most likely gained entry through the skin or the epithelia and mucosae of the digestive tract. Some pigs acquired subclinical infections in which no virus excretion was detected and no transmission of infection to susceptible pigs took place over a period of 5 weeks.
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Selected References
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- Burrows R., Greig A., Goodridge D. Swine vesicular disease. Res Vet Sci. 1973 Jul;15(1):141–144. [PubMed] [Google Scholar]
- Burrows R. The infectivity assay of foot-and-mouth disease virus in pigs. J Hyg (Lond) 1966 Dec;64(4):419–429. doi: 10.1017/s0022172400040729. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dawe P. S., Forman A. J., Smale C. J. A preliminary investigation of the swine vesicular disease epidemic in Britain. Nature. 1973 Feb 23;241(5391):540–542. doi: 10.1038/241540a0. [DOI] [PubMed] [Google Scholar]
- Mowat G. N., Darbyshire J. H., Huntley J. F. Differentiation of a vesicular disease of pigs in Hong Kong from foot-and-mouth disease. Vet Rec. 1972 May 27;90(22):618–621. doi: 10.1136/vr.90.22.618. [DOI] [PubMed] [Google Scholar]
- Nardelli L., Lodetti E., Gualandi G. L., Burrows R., Goodridge D., Brown F., Cartwright B. A foot and mouth disease syndrome in pigs caused by an enterovirus. Nature. 1968 Sep 21;219(5160):1275–1276. doi: 10.1038/2191275a0. [DOI] [PubMed] [Google Scholar]
- Sellers R. F., Herniman K. A. The airborne excretion by pigs of swine vesicular disease virus. J Hyg (Lond) 1974 Feb;72(1):61–65. doi: 10.1017/s0022172400023214. [DOI] [PMC free article] [PubMed] [Google Scholar]