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. 1984 Oct;160(1):288–293. doi: 10.1128/jb.160.1.288-293.1984

Mutagenesis of Neisseria gonorrhoeae: absence of error-prone repair.

L A Campbell, R E Yasbin
PMCID: PMC214714  PMID: 6434520

Abstract

The lethal and mutagenic effects of various mutagens on Neisseria gonorrhoeae were investigated. Lethality studies demonstrated that N. gonorrhoeae was relatively sensitive to ethyl methanesulfonate, UV light, and methyl methanesulfonate. Although N. gonorrhoeae was readily mutated by ethyl methanesulfonate and N-methyl-N'-nitro-N-nitrosoguanidine for the three genetic markers assayed, no increase in the mutation frequency was observed for any of the selective markers after UV irradiation or methyl methanesulfonate treatment. These results suggest that N. gonorrhoeae lacks an error-prone repair mechanism.

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Selected References

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