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Anesthesia Progress logoLink to Anesthesia Progress
. 1985 Mar-Apr;32(2):65–68.

Long-Acting Local Anesthetics in Oral Surgery: An Experimental Evaluation of Bupivacaine and Etidocaine for Infiltration Anesthesia

Karlhâkan Danielsson, Hans Evers, Åke Nordenram
PMCID: PMC2148528  PMID: 3859232

Abstract

The effect of bupivacaine 7.5 mg/ml with epinephrine 5μg/ml, etidocaine 15 mg/ml with epinephrine 5 μg/ml, and lidocaine 20 mg/ml with epinephrine 12.5 μg/ml was studied when used for oral infiltration anesthesia. Twenty healthy volunteers took part in the experimental and double-blind study. One ml of the respective anesthetic solution was deposited supraperiosteally in the apical area of the maxillary right lateral incisor. Onset time, frequency of analgesia, gingival spread, and duration of tooth analgesia were studied and duration of soft-tissue numbness registered. The present investigation showed that lidocaine had a shorter onset time compared with bupivacaine. No difference with regard to frequency was found. Bupivacaine and etidocaine had a longer period of soft-tissue numbness, but a significantly shorter duration of tooth analgesia than lidocaine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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