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. 1998 May;77(10):1686–1688. doi: 10.1038/bjc.1998.278

Neuromuscular toxicities of paclitaxel 210 mg m(-2) by 3-hour infusion.

H Kunitoh 1, N Saijo 1, K Furuse 1, K Noda 1, M Ogawa 1
PMCID: PMC2150075  PMID: 9635850

Abstract

We retrospectively analysed neuromuscular toxicity associated with paclitaxel 210 mg m(-2) given by 3-h infusion in 247 patients. The severity correlated significantly with total cumulative dose, but could not be predicted by the pretreatment clinical variables or by pharmacokinetic parameters. The toxicity tended to occur in early treatment cycles.

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Selected References

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