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British Journal of Cancer logoLink to British Journal of Cancer
. 1998 Apr;77(7):1045–1047. doi: 10.1038/bjc.1998.174

Lack of involvement of known oncogenic DNA viruses in Epstein-Barr virus-negative Hodgkin's disease.

A A Armstrong 1, L Shield 1, A Gallagher 1, R F Jarrett 1
PMCID: PMC2150138  PMID: 9569037

Abstract

Epstein-Barr virus (EBV) is associated with around one-third of cases, but young adult cases are rarely EBV associated. In this study, known oncogenic DNA viruses, including human adenoviruses, papovaviruses and the human herpesviruses-6 (HHV-6) and -8 (HHV-8) were not detected in Hodgkin's disease lesions. These results suggest that an as yet unidentified infectious agent is involved in the pathogenesis of non-EBV-associated Hodgkin's disease.

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Selected References

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