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. 1979 Jun;138(3):762–769. doi: 10.1128/jb.138.3.762-769.1979

Genetic basis for colonial variation in Neisseria gonorrhoeae.

L Norlander, J Davies, A Norqvist, S Normark
PMCID: PMC218102  PMID: 110769

Abstract

When the piliated colony types of Neisseria gonorrhoeae, which predominate in recent isolates, were nonselectively subcultured in vitro, they gave rise to large numbers of nonpiliated, avirulent colonial variants. Evidence is presented to show that most of this variation occurs after active growth has ceased and that the variation is sensitive to the action of deoxyribonuclease. We suggest that this variation is a result of transformation. A second variation in colonial morphology involved differing levels of "colony opacity-associated proteins" in the outer membrane. This variation was also inhibited by the presence of deoxyribonuclease, but the genetic basis for it is not as yet clear.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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