Abstract
Deoxyribonucleic acid polymerase I-directed repair synthesis can be selectively measured in toluene-treated Escherichia coli cells exposed to alkylating chemicals such as N-methyl-N'-nitro-N-nitrosoguanidine. Prior growth of the cells in the presence of a low dose of N-methyl-N'-nitro-N-nitrosoguanidine results in an enhanced deoxyribonucleic acid polymerase I-directed repair synthesis and an increase in single-strand breaks.
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- Billen D., Hellermann G. R. Role of deoxyribonucleic acid polymerases and deoxyribonucleic acid ligase in x-ray-induced repair synthesis in toluene-treated Escherichia coli K-12. J Bacteriol. 1976 May;126(2):785–793. doi: 10.1128/jb.126.2.785-793.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Billen D., Hellermann G. R. The role of DNA polymerases in DNA repair in Escherichia coli: DNA polymerase I-dependent repair following chemical alkylation of permeabilized bacteria. Chem Biol Interact. 1977 Sep;18(3):365–380. doi: 10.1016/0009-2797(77)90022-9. [DOI] [PubMed] [Google Scholar]
- Billen D., Hellermann G. Depression by NAD of x-ray-induced repair-type DNA synthesis in toluene-treated Bacillus subtilis. Biochim Biophys Acta. 1975 Apr 2;383(4):379–387. doi: 10.1016/0005-2787(75)90307-x. [DOI] [PubMed] [Google Scholar]
- Dürwald H., Hoffmann-Berling H. Endonuclease-I-deficient and ribonuclease I-deficient Escherichia coli mutants. J Mol Biol. 1968 Jul 14;34(2):331–346. doi: 10.1016/0022-2836(68)90257-x. [DOI] [PubMed] [Google Scholar]
- Howard-Flanders P., Theriot L. Mutants of Escherichia coli K-12 defective in DNA repair and in genetic recombination. Genetics. 1966 Jun;53(6):1137–1150. doi: 10.1093/genetics/53.6.1137. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jeggo P., Defais T. M., Samson L., Schendel P. An adaptive response of E. coli to low levels of alkylating agent: comparison with previously characterised DNA repair pathways. Mol Gen Genet. 1977 Nov 29;157(1):1–9. doi: 10.1007/BF00268680. [DOI] [PubMed] [Google Scholar]
- Lindahl T. New class of enzymes acting on damaged DNA. Nature. 1976 Jan 1;259(5538):64–66. doi: 10.1038/259064a0. [DOI] [PubMed] [Google Scholar]
- Samson L., Cairns J. A new pathway for DNA repair in Escherichia coli. Nature. 1977 May 19;267(5608):281–283. doi: 10.1038/267281a0. [DOI] [PubMed] [Google Scholar]
- Schendel P. F., Defais M., Jeggo P., Samson L., Cairns J. Pathways of mutagenesis and repair in Escherichia coli exposed to low levels of simple alkylating agents. J Bacteriol. 1978 Aug;135(2):466–475. doi: 10.1128/jb.135.2.466-475.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Witkin E. M. Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. Bacteriol Rev. 1976 Dec;40(4):869–907. doi: 10.1128/br.40.4.869-907.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]