Abstract
An altered rho gene product affects expression of the his operon of Escherichia coli. The effect is greater for the operator proximal portion of the his operon than for the operator distal portion. This "rho effect" appears to be independent of the site of action of hisT-altered histidyl-tRNA.
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- AMES B. N., HARTMAN P. E., JACOB F. Chromosomal alterations affecting the regulation of histidine biosynthetic enzymes in Salmonella. J Mol Biol. 1963 Jul;7:23–42. doi: 10.1016/s0022-2836(63)80016-9. [DOI] [PubMed] [Google Scholar]
- Artz S. W., Broach J. R. Histidine regulation in Salmonella typhimurium: an activator attenuator model of gene regulation. Proc Natl Acad Sci U S A. 1975 Sep;72(9):3453–3457. doi: 10.1073/pnas.72.9.3453. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bachmann B. J., Low K. B., Taylor A. L. Recalibrated linkage map of Escherichia coli K-12. Bacteriol Rev. 1976 Mar;40(1):116–167. doi: 10.1128/br.40.1.116-167.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bertrand K., Korn L., Lee F., Platt T., Squires C. L., Squires C., Yanofsky C. New features of the regulation of the tryptophan operon. Science. 1975 Jul 4;189(4196):22–26. doi: 10.1126/science.1094538. [DOI] [PubMed] [Google Scholar]
- Bertrand K., Squires C., Yanofsky C. Transcription termination in vivo in the leader region of the tryptophan operon of Escherichia coli. J Mol Biol. 1976 May 15;103(2):319–337. doi: 10.1016/0022-2836(76)90315-6. [DOI] [PubMed] [Google Scholar]
- Bruni C. B., Colantuoni V., Sbordone L., Cortese R., Blasi F. Biochemical and regulatory properties of Escherichia coli K-12 hisT mutants. J Bacteriol. 1977 Apr;130(1):4–10. doi: 10.1128/jb.130.1.4-10.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Das A., Court D., Adhya S. Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho. Proc Natl Acad Sci U S A. 1976 Jun;73(6):1959–1963. doi: 10.1073/pnas.73.6.1959. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ely B., Ciesla Z. Internal promoter P2 of the histidine operon of Salmonella typhimurium. J Bacteriol. 1974 Nov;120(2):984–986. doi: 10.1128/jb.120.2.984-986.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Inoko H., Shigesada K., Imai M. Isolation and characterization of conditional-lethal rho mutants of Escherichia coli. Proc Natl Acad Sci U S A. 1977 Mar;74(3):1162–1166. doi: 10.1073/pnas.74.3.1162. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jackson E. N., Yanofsky C. Thr region between the operator and first structural gene of the tryptophan operon of Escherichia coli may have a regulatory function. J Mol Biol. 1973 May 5;76(1):89–101. doi: 10.1016/0022-2836(73)90082-x. [DOI] [PubMed] [Google Scholar]
- Kasai T. Regulation of the expression of the histidine operon in Salmonella typhimurium. Nature. 1974 Jun 7;249(457):523–527. doi: 10.1038/249523a0. [DOI] [PubMed] [Google Scholar]
- Kleeman J., Parsons S. M. A sensitive assay for the reverse reaction of the first histidine biosynthetic enzyme. Anal Biochem. 1975 Sep;68(1):236–241. doi: 10.1016/0003-2697(75)90700-9. [DOI] [PubMed] [Google Scholar]
- Korn L. J., Yanofsky C. Polarity suppressors defective in transcription termination at the attenuator of the tryptophan operon of Escherichia coli have altered rho factor. J Mol Biol. 1976 Sep 15;106(2):231–241. doi: 10.1016/0022-2836(76)90082-6. [DOI] [PubMed] [Google Scholar]
- Korn L. J., Yanofsky C. Polarity suppressors increase expression of the wild-type tryptophan operon of Escherichia coli. J Mol Biol. 1976 May 15;103(2):395–409. doi: 10.1016/0022-2836(76)90319-3. [DOI] [PubMed] [Google Scholar]
- Lawther R. P., Hatfield W. Biochemical characterization of an Escherichia coli hisT strain. J Bacteriol. 1977 Apr;130(1):552–557. doi: 10.1128/jb.130.1.552-557.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Richardson J. P., Fink P., Blanchard K., Macy M. Bacteria with defective rho factors suppress the effects of N mutations in bacteriophage lambda. Mol Gen Genet. 1977 May 20;153(1):81–85. doi: 10.1007/BF01035999. [DOI] [PubMed] [Google Scholar]
- Roberts J. W. Termination factor for RNA synthesis. Nature. 1969 Dec 20;224(5225):1168–1174. doi: 10.1038/2241168a0. [DOI] [PubMed] [Google Scholar]
- Smith J. M., Smolin D. E., Umbarger H. E. Polarity and the regulation of the ilv gene cluster in Escherichia coli strain K-12. Mol Gen Genet. 1976 Oct 18;148(2):111–124. doi: 10.1007/BF00268374. [DOI] [PubMed] [Google Scholar]
- Wasmuth J. J., Umbarger H. E. Effect of isoleucine, valine, or leucine starvation on the potential for formation of the branched-chain amino acid biosynthetic enzymes. J Bacteriol. 1973 Nov;116(2):548–561. doi: 10.1128/jb.116.2.548-561.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Winkler M. E. Expression of the histidine operon in rho mutants of Escherichia coli. J Bacteriol. 1978 Aug;135(2):721–725. doi: 10.1128/jb.135.2.721-725.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]