Skip to main content
PMC home page
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1966 Sep;56(3):946–953. doi: 10.1073/pnas.56.3.946

Studies on the mechanism of hormone induction of alkaline phosphatase in human cell cultures, II. Rate of enzyme synthesis and properties of base level and induced enzymes.

M J Griffin, R P Cox
PMCID: PMC219951  PMID: 5230189

Full text

PDF
947

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BITENSKY M. W., YIELDING K. L., TOMKINS G. M. THE REVERSAL BY ORGANIC MERCURIALS OF "ALLOSTERIC" CHANGES IN GLUTAMATE DEHYDROGENASE. J Biol Chem. 1965 Feb;240:668–673. [PubMed] [Google Scholar]
  2. COX R. P., MACLEOD C. M. Alkaline phosphatase content and the effects of prednisolone on mammalian cells in culture. J Gen Physiol. 1962 Jan;45:439–485. doi: 10.1085/jgp.45.3.439. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. COX R. P., MACLEOD C. M. Hormonal induction of alkaline phosphatase in human cells in tissue culture. Nature. 1961 Apr 1;190:85–87. doi: 10.1038/190085a0. [DOI] [PubMed] [Google Scholar]
  4. COX R. P., MACLEOD C. M. REGULATION OF ALKALINE PHOSPHATASE IN HUMAN CELL CULTURES. Cold Spring Harb Symp Quant Biol. 1964;29:233–251. doi: 10.1101/sqb.1964.029.01.027. [DOI] [PubMed] [Google Scholar]
  5. EAGLE H. Amino acid metabolism in mammalian cell cultures. Science. 1959 Aug 21;130(3373):432–437. doi: 10.1126/science.130.3373.432. [DOI] [PubMed] [Google Scholar]
  6. FISHMAN W. H., GREEN S., INGLIS N. I. Organ-specific behavior exhibited by rat intestine and liver alkaline phosphatase. Biochim Biophys Acta. 1962 Aug 13;62:363–375. doi: 10.1016/0006-3002(62)90266-4. [DOI] [PubMed] [Google Scholar]
  7. GRABAR P., WILLIAMS C. A. Méthode permettant l'étude conjuguée des proprietés électrophorétiques et immunochimiques d'un mélange de protéines; application au sérum sanguin. Biochim Biophys Acta. 1953 Jan;10(1):193–194. doi: 10.1016/0006-3002(53)90233-9. [DOI] [PubMed] [Google Scholar]
  8. HERZ F., NITOWSKY H. M. Alkaline phosphatase activity of human cell cultures: kinetic and physical-chemical properties. Arch Biochem Biophys. 1962 Mar;96:506–515. doi: 10.1016/0003-9861(62)90328-4. [DOI] [PubMed] [Google Scholar]
  9. KENNEY F. T. Induction of tyrosine-alpha-ketoglutarate transaminase in rat liver. IV. Evidence for an increase in the rate of enzyme synthesis. J Biol Chem. 1962 Nov;237:3495–3498. [PubMed] [Google Scholar]
  10. MORTON R. K. The purification of aklaline phosphatases of animal tissues. Biochem J. 1954 Aug;57(4):595–603. doi: 10.1042/bj0570595. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. McLIMANS W. F., DAVIS E. V., GLOVER F. L., RAKE G. W. The submerged culture of mammalian cells; the spinner culture. J Immunol. 1957 Nov;79(5):428–433. [PubMed] [Google Scholar]
  12. NITOWSKY H. M., HERZ F. Hormonal regulation of alkaline phosphatase in dispersed cell cultures. Biochem Biophys Res Commun. 1963 May 22;11:261–266. doi: 10.1016/0006-291x(63)90554-0. [DOI] [PubMed] [Google Scholar]
  13. SCHIMKE R. T., SWEENEY E. W., BERLIN C. M. THE ROLES OF SYNTHESIS AND DEGRADATION IN THE CONTROL OF RAT LIVER TRYPTOPHAN PYRROLASE. J Biol Chem. 1965 Jan;240:322–331. [PubMed] [Google Scholar]
  14. SEGAL H. L., KIM Y. S. GLUCOCORTICOID STIMULATION OF THE BIOSYNTHESIS OF GLUTAMIC-ALANINE TRANSAMINASE. Proc Natl Acad Sci U S A. 1963 Nov;50:912–918. doi: 10.1073/pnas.50.5.912. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. TOMKINS G. M., YIELDING K. L. Regulation of the enzymic activity of glutamic dehydrogenase mediated by changes in its structure. Cold Spring Harb Symp Quant Biol. 1961;26:331–341. doi: 10.1101/sqb.1961.026.01.040. [DOI] [PubMed] [Google Scholar]
  16. WAYMOUTH C. Rapid proliferation of sublines of NCTC clone 929 (strain L) mouse cells in a simple chemically defined medium (MB 752/1). J Natl Cancer Inst. 1959 May;22(5):1003–1017. doi: 10.1093/jnci/22.5.1003. [DOI] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES