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Proceedings of the AMIA Symposium logoLink to Proceedings of the AMIA Symposium
. 1999:440–444.

Modeling empiric antibiotic therapy evaluation of QID.

H Warner Jr 1, L Reimer 1, D Suvinier 1, L Li 1, M Nelson 1
PMCID: PMC2232727  PMID: 10566397

Abstract

At AMIA 1997, we reported on the design and development of a new computer-based tool, called QID, for empiric antibiotic decision support. QID was designed to help physicians identify the antibiotic regimens with the highest probability of covering the pathogens that are most likely to be present in individual patients. QID creates a list of antibiotics, ordered by potential benefit in treatment, for a patient with a suspected infection before culture results are available. Since our initial publication, a "before and after" study has been done using 20 internal medicine residents and the same number of internal medicine attendings. In order to test the hypothesis that physician's would make more appropriate empiric antibiotic choices with the aid of QID, we chose University of Utah physicians and had each evaluate four infectious disease cases that were abstracted from medical record infectious disease cases. Immediately following their initial review and determination of antibiotic therapy for each case, the study participants were presented with QID's antibiotic recommendations on the same case to see if this information would change their initial drug regimen. The tool was shown to have a greater impact on the most difficult cases but statistically improved scores overall (p < .001). Details of our study design and results are presented.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Buckwold F. J., Ronald A. R. Antimicrobial misuse--effects and suggestions for control. J Antimicrob Chemother. 1979 Mar;5(2):129–136. doi: 10.1093/jac/5.2.129. [DOI] [PubMed] [Google Scholar]
  2. Evans R. S., Classen D. C., Pestotnik S. L., Lundsgaarde H. P., Burke J. P. Improving empiric antibiotic selection using computer decision support. Arch Intern Med. 1994 Apr 25;154(8):878–884. [PubMed] [Google Scholar]
  3. Kassirer J. P. The principles of clinical decision making: an introduction to decision analysis. Yale J Biol Med. 1976 May;49(2):149–164. [PMC free article] [PubMed] [Google Scholar]
  4. Shortliffe E. H., Axline S. G., Buchanan B. G., Merigan T. C., Cohen S. N. An artificial intelligence program to advise physicians regarding antimicrobial therapy. Comput Biomed Res. 1973 Dec;6(6):544–560. doi: 10.1016/0010-4809(73)90029-3. [DOI] [PubMed] [Google Scholar]

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