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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1969 Dec;64(4):1396–1403. doi: 10.1073/pnas.64.4.1396

NUCLEAR MAGNETIC RESONANCE STUDIES OF THE STRUCTURE AND BINDING SITES OF ENZYMES, X. PREPARATION OF SELECTIVELY DEUTERATED ANALOGS OF STAPHYLOCOCCAL NUCLEASE

I Putter 1, A Barreto 1, J L Markley 1, O Jardetzky 1
PMCID: PMC223298  PMID: 5271760

Abstract

Five different selectively deuterated analogs of staphylococcal nuclease (Foggi) were prepared having all but a selected few hydrogen atoms in the enzyme molecule replaced by deuterium. The 1H-NMR spectra of these analogs are extremely simplified, since they consist of lines arising only from the remaining protonated sites.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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