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. 1969 Jun;63(2):496–503. doi: 10.1073/pnas.63.2.496

A MUSCARONE-BINDING MATERIAL IN ELECTROPLAX AND ITS RELATION TO THE ACETYLCHOLINE RECEPTOR, I. CENTRIFUGAL ASSAY

R D O'Brien 1, L P Gilmour 1
PMCID: PMC223591  PMID: 5257140

Abstract

A muscarone-binding material has been found in Torpedo electroplax. The material behaves in several ways as one would expect of the binding component of the acetylcholine receptor, especially in its high affinity for muscarone (approximate K = 7 × 10-6M), acetylcholine (approximate K = 1.1 × 10-6M), curare, and nicotine, and its insensitivity to noncholinergic agents; the reversibility of its muscarone binding; and its suitably small amount (about 1.8 nmole/gm). The material appears not to be acetylcholinesterase.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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