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. 1969 Mar;62(3):644–649. doi: 10.1073/pnas.62.3.644

23Na NUCLEAR MAGNETIC RESONANCE RELAXATION STUDIES OF SODIUM ION INTERACTION WITH SOLUBLE RNA*

Thomas L James 1,†, Joseph H Noggle 1
PMCID: PMC223645  PMID: 5256995

Abstract

Interactions between 23Na+ and soluble RNA in aqueous solution are studied with the use of 23Na nuclear magnetic resonance. At low concentrations of NaCl, the interactions obey a simple equilibrium model with a formation constant log (Kf)3 = 2.8 ± 0.3. The relaxation rate of the bound sodium is found to be T1B-1 = 222 ± 19 sec-1 compared to that of free sodium T1F-1 = 17.5 sec-1. At high NaCl concentrations, the system deviates from the model, possibly owing to aggregation of the soluble RNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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