Skip to main content
PMC home page
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1967 Apr;57(4):1062–1067. doi: 10.1073/pnas.57.4.1062

Translation of the genetic message, IV. UAA as a chain termination codon.

J A Last, W M Stanley Jr, M Salas, M B Hille, A J Wahba, S Ochoa
PMCID: PMC224655  PMID: 5231346

Full text

PDF
1066

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brenner S., Stretton A. O., Kaplan S. Genetic code: the 'nonsense' triplets for chain termination and their suppression. Nature. 1965 Jun 5;206(988):994–998. doi: 10.1038/206994a0. [DOI] [PubMed] [Google Scholar]
  2. Bretscher M. S., Goodman H. M., Menninger J. R., Smith J. D. Polypeptide chain termination using synthetic polynucleotides. J Mol Biol. 1965 Dec;14(2):634–639. doi: 10.1016/s0022-2836(65)80219-4. [DOI] [PubMed] [Google Scholar]
  3. Capecchi M. R. Initiation of E. coli proteins. Proc Natl Acad Sci U S A. 1966 Jun;55(6):1517–1524. doi: 10.1073/pnas.55.6.1517. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Clark B. F., Marcker K. A. N-formyl-methionyl-sigma-ribonucleic acid and chain initiation in protein biosynthesis. Polypeptide synthesis directed by a bacteriophage ribonucleic acid in a cell-free system. Nature. 1966 Jul 23;211(5047):378–380. doi: 10.1038/211378a0. [DOI] [PubMed] [Google Scholar]
  5. Ganoza M. C., Nakamoto T. Studies on the mechanism of polypeptide chain termination in cell-free extracts of E. coli. Proc Natl Acad Sci U S A. 1966 Jan;55(1):162–169. doi: 10.1073/pnas.55.1.162. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Garen A., Garen S., Wilhelm R. C. Suppressor genes for nonsense mutations. I. The Su-1, Su-2 and Su-3 genes of Escherichia coli. J Mol Biol. 1965 Nov;14(1):167–178. doi: 10.1016/s0022-2836(65)80238-8. [DOI] [PubMed] [Google Scholar]
  7. Jones D. S., Nishimura S., Khorana H. G. Studies on polynucleotides. LVI. Further syntheses, in vitro of copolypeptides containing two amino acids in alternating sequence dependent upon DNA-like polymers containing two nucleotides in alternating sequence. J Mol Biol. 1966 Apr;16(2):454–472. doi: 10.1016/s0022-2836(66)80185-7. [DOI] [PubMed] [Google Scholar]
  8. Nirenberg M., Leder P., Bernfield M., Brimacombe R., Trupin J., Rottman F., O'Neal C. RNA codewords and protein synthesis, VII. On the general nature of the RNA code. Proc Natl Acad Sci U S A. 1965 May;53(5):1161–1168. doi: 10.1073/pnas.53.5.1161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. SARABHAI A. S., STRETTON A. O., BRENNER S., BOLLE A. CO-LINEARITY OF THE GENE WITH THE POLYPEPTIDE CHAIN. Nature. 1964 Jan 4;201:13–17. doi: 10.1038/201013a0. [DOI] [PubMed] [Google Scholar]
  10. STRETTON A. O., BRENNER S. MOLECULAR CONSEQUENCES OF THE AMBER MUTATION AND ITS SUPPRESSION. J Mol Biol. 1965 Jun;12:456–465. doi: 10.1016/s0022-2836(65)80268-6. [DOI] [PubMed] [Google Scholar]
  11. Salas M., Hille M. B., Last J. A., Wahba A. J., Ochoa S. Translation of the genetic message, ii. Effect of initiation factors on the binding of formyl-methionyl-trna to ribosomes. Proc Natl Acad Sci U S A. 1967 Feb;57(2):387–394. doi: 10.1073/pnas.57.2.387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Salas M., Smith M. A., Stanley W. M., Jr, Wahba A. J., Ochoa S. Direction of reading of the genetic message. J Biol Chem. 1965 Oct;240(10):3988–3995. [PubMed] [Google Scholar]
  13. Stanley W. M., Jr, Salas M., Wahba A. J., Ochoa S. Translation of the genetic message: factors involved in the initiation of protein synthesis. Proc Natl Acad Sci U S A. 1966 Jul;56(1):290–295. doi: 10.1073/pnas.56.1.290. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Takanami M., Yan Y. The release of polypeptide chains from ribosomes in cell-free amino acid-incorporating systems by specific combinations of bases in synthetic polyribonucleotides. Proc Natl Acad Sci U S A. 1965 Nov;54(5):1450–1458. doi: 10.1073/pnas.54.5.1450. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Viñuela E., Salas M., Ochoa S. Translation of the genetic message, iii. Formylmethionine as initiator of proteins programed by polycistronic messenger RNA. Proc Natl Acad Sci U S A. 1967 Mar;57(3):729–734. doi: 10.1073/pnas.57.3.729. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. WEIGERT M. G., GAREN A. AMINO ACID SUBSTITUTIONS RESULTING FROM SUPPRESSION OF NONSENSE MUTATIONS. I. SERINE INSERTION BY THE SU-1 SUPPRESSOR GENE. J Mol Biol. 1965 Jun;12:448–455. doi: 10.1016/s0022-2836(65)80267-4. [DOI] [PubMed] [Google Scholar]
  17. Webster R. E., Engelhardt D. L., Zinder N. D. In vitro protein synthesis: chain initiation. Proc Natl Acad Sci U S A. 1966 Jan;55(1):155–161. doi: 10.1073/pnas.55.1.155. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Weigert M. G., Garen A. Base composition of nonsense codons in E. coli. Evidence from amino-acid substitutions at a tryptophan site in alkaline phosphatase. Nature. 1965 Jun 5;206(988):992–994. doi: 10.1038/206992a0. [DOI] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES