Skip to main content
PMC home page
British Journal of Cancer logoLink to British Journal of Cancer
. 1989 Feb;59(2):231–235. doi: 10.1038/bjc.1989.47

Survival and prognostic factors in differentiated thyroid cancer--a multivariate analysis of 1,055 cases.

S O Thoresen 1, L A Akslen 1, E Glattre 1, T Haldorsen 1, E V Lund 1, M Schoultz 1
PMCID: PMC2246999  PMID: 2930688

Abstract

Survival (5- and 10-year) and prognostic factors of all differentiated thyroid cancer patients (n = 1,055) occurring in Norway in 1970-79 are presented. The multivariate analysis (GLIM) revealed that stage and age were the only significant prognostic factors. Sex and histological type could not be proved to be of major prognostic value. The decline in relative survival with age was different in the three stages, appearing as a continuous decrease in stage 3, while in stage 1 the decrease was present only in patients older than 75 years.

Full text

PDF
232

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Byar D. P., Green S. B., Dor P., Williams E. D., Colon J., van Gilse H. A., Mayer M., Sylvester R. J., van Glabbeke M. A prognostic index for thyroid carcinoma. A study of the E.O.R.T.C. Thyroid Cancer Cooperative Group. Eur J Cancer. 1979 Aug;15(8):1033–1041. doi: 10.1016/0014-2964(79)90291-3. [DOI] [PubMed] [Google Scholar]
  2. Cady B., Rossi R., Silverman M., Wool M. Further evidence of the validity of risk group definition in differentiated thyroid carcinoma. Surgery. 1985 Dec;98(6):1171–1178. [PubMed] [Google Scholar]
  3. Hannequin P., Liehn J. C., Delisle M. J. Multifactorial analysis of survival in thyroid cancer. Pitfalls of applying the results of published studies to another population. Cancer. 1986 Oct 15;58(8):1749–1755. doi: 10.1002/1097-0142(19861015)58:8<1749::aid-cncr2820580828>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
  4. Joensuu H., Klemi P., Eerola E., Tuominen J. Influence of cellular DNA content on survival in differentiated thyroid cancer. Cancer. 1986 Dec 1;58(11):2462–2467. doi: 10.1002/1097-0142(19861201)58:11<2462::aid-cncr2820581119>3.0.co;2-e. [DOI] [PubMed] [Google Scholar]
  5. Mazzaferri E. L. Papillary thyroid carcinoma: factors influencing prognosis and current therapy. Semin Oncol. 1987 Sep;14(3):315–332. [PubMed] [Google Scholar]
  6. Saxén E., Franssila K., Bjarnason O., Normann T., Ringertz N. Observer variation in histologic classification of thyroid cancer. Acta Pathol Microbiol Scand A. 1978 Nov;86A(6):483–486. doi: 10.1111/j.1699-0463.1978.tb02073.x. [DOI] [PubMed] [Google Scholar]
  7. Simpson W. J., McKinney S. E. Canadian survey of thyroid cancer. Can Med Assoc J. 1985 Apr 15;132(8):925–931. [PMC free article] [PubMed] [Google Scholar]
  8. Simpson W. J., McKinney S. E., Carruthers J. S., Gospodarowicz M. K., Sutcliffe S. B., Panzarella T. Papillary and follicular thyroid cancer. Prognostic factors in 1,578 patients. Am J Med. 1987 Sep;83(3):479–488. doi: 10.1016/0002-9343(87)90758-3. [DOI] [PubMed] [Google Scholar]
  9. Tennvall J., Biörklund A., Möller T., Ranstam J., Akerman M. Prognostic factors of papillary, follicular and medullary carcinomas of the thyroid gland. Retrospective multivariate analysis of 216 patients with a median follow-up of 11 years. Acta Radiol Oncol. 1985 Jan-Feb;24(1):17–24. doi: 10.3109/02841868509134360. [DOI] [PubMed] [Google Scholar]
  10. Thoresen S. O., Myking O., Glattre E., Rootwelt K., Andersen A., Foss O. P. Serum thyroglobulin as a preclinical tumour marker in subgroups of thyroid cancer. Br J Cancer. 1988 Jan;57(1):105–108. doi: 10.1038/bjc.1988.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Tubiana M., Schlumberger M., Rougier P., Laplanche A., Benhamou E., Gardet P., Caillou B., Travagli J. P., Parmentier C. Long-term results and prognostic factors in patients with differentiated thyroid carcinoma. Cancer. 1985 Feb 15;55(4):794–804. doi: 10.1002/1097-0142(19850215)55:4<794::aid-cncr2820550418>3.0.co;2-z. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES