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. 1987 Oct;99(2):235–239. doi: 10.1017/s0950268800067698

Legionella pneumophila: monoclonal antibody typing of clinical and environmental isolates.

R J Brindle 1, P J Stannett 1, J O Tobin 1
PMCID: PMC2249261  PMID: 3678387

Abstract

Forty-one clinical isolates of Legionella pneumophila from sporadic cases of legionella pneumonia were collected from laboratories throughout the United Kingdom and were compared with 300 routine environmental isolates using two panels of monoclonal antibodies, covering serogroups 1-10. Eighty-five per cent of the clinical isolates belonged to the subgroup Pontiac of serogroup 1, whilst only 13% of the environmental isolates did. Approximately half of the clinical isolates tested came from patients with a recent history of foreign travel, mainly to southern Europe.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Edelstein P. H. Improved semiselective medium for isolation of Legionella pneumophila from contaminated clinical and environmental specimens. J Clin Microbiol. 1981 Sep;14(3):298–303. doi: 10.1128/jcm.14.3.298-303.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Edelstein P. H., Nakahama C., Tobin J. O., Calarco K., Beer K. B., Joly J. R., Selander R. K. Paleoepidemiologic investigation of Legionnaires disease at Wadsworth Veterans Administration Hospital by using three typing methods for comparison of legionellae from clinical and environmental sources. J Clin Microbiol. 1986 Jun;23(6):1121–1126. doi: 10.1128/jcm.23.6.1121-1126.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Joly J. R., McKinney R. M., Tobin J. O., Bibb W. F., Watkins I. D., Ramsay D. Development of a standardized subgrouping scheme for Legionella pneumophila serogroup 1 using monoclonal antibodies. J Clin Microbiol. 1986 Apr;23(4):768–771. doi: 10.1128/jcm.23.4.768-771.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Joly J. R., Ramsay D. Use of monoclonal antibodies in the diagnosis and epidemiologic studies of legionellosis. Clin Lab Med. 1985 Sep;5(3):561–574. [PubMed] [Google Scholar]
  5. McKinney R. M., Thacker L., Wells D. E., Wong M. C., Jones W. J., Bibb W. F. Monoclonal antibodies to Legionella pneumophila serogroup 1: possible applications in diagnostic tests and epidemiologic studies. Zentralbl Bakteriol Mikrobiol Hyg A. 1983 Jul;255(1):91–95. [PubMed] [Google Scholar]
  6. Selander R. K., McKinney R. M., Whittam T. S., Bibb W. F., Brenner D. J., Nolte F. S., Pattison P. E. Genetic structure of populations of Legionella pneumophila. J Bacteriol. 1985 Sep;163(3):1021–1037. doi: 10.1128/jb.163.3.1021-1037.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Tobin J. O., Watkins I. D., Woodhead S., Mitchell R. G. Epidemiological studies using monoclonal antibodies to Legionella pneumophila serogroup 1. Isr J Med Sci. 1986 Oct;22(10):711–714. [PubMed] [Google Scholar]
  8. Watkins I. D., Tobin J. O., Dennis P. J., Brown W., Newnham R., Kurtz J. B. Legionella pneumophila serogroup 1 subgrouping by monoclonal antibodies--an epidemiological tool. J Hyg (Lond) 1985 Oct;95(2):211–216. doi: 10.1017/s0022172400062641. [DOI] [PMC free article] [PubMed] [Google Scholar]

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