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. 1987 Oct;99(2):463–469. doi: 10.1017/s0950268800067960

Isolation of Neisseria meningitidis strains with increase of penicillin minimal inhibitory concentrations

J A Sáez-Nieto, D Fontanals, J Garcia De Jalon, V Martinez De Artola, P Peña, M A Morera, R Verdaguer, I Sanfeliu, C Belio-Blasco, J L Perez-Saenz, J Casal
PMCID: PMC2249299  PMID: 3119361

Abstract

We report the isolation and characterization of ten strains showing an increase in the minimal inhibitory concentrations to penicillin (MICs > 0·1 μg/ml), and describe the epidemiological, clinical and microbiological features.

The susceptibility of 3432 meningococcal strains isolated from patients in the recent epidemic wave (1978-86) in Spain, to several antimicrobial agents used in the treatment and chemoprophylaxis of meningococcal infection has been tested. Most were resistant to sulphadiazine but sensitive to other antibiotics.

The possible existence of a new pattern of behaviour of meningococcal to penicillin is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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