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Epidemiology and Infection logoLink to Epidemiology and Infection
. 1993 Oct;111(2):407–412. doi: 10.1017/s0950268800057095

Distinct yearly change of serotype distribution of human rotavirus in Thailand as determined by ELISA and PCR.

Y Pongsuwanna 1, K Taniguchi 1, F Wakasugi 1, Y Sutivijit 1, M Chiwakul 1, P Warachit 1, C Jayavasu 1, S Urasawa 1
PMCID: PMC2271393  PMID: 8405164

Abstract

A total of 241 group A rotavirus-positive stool samples collected from diarrhoeic patients in Thailand between July 1988 and June 1991 were characterized for their serotypes by enzyme-linked immunosorbent assay (ELISA) using serotype-specific monoclonal antibodies and by a polymerase chain reaction (PCR). In July 1988-June 1989, serotype 1 was the most prevalent (63.4%), followed by serotype 4 (11.0%) and serotype 2 (8.5%). In July 1989-June 1990, 59.8% were serotype 1, 24.3% were serotype 2, and 6.1% were serotype 3. In contrast, in July 1990-June 1991, serotype 3 was detected in the highest frequency (40.5%), 29.9% were serotype 1, and 27.3% were serotype 2. Thus, a distinct yearly change of serotype distribution of rotavirus in Thailand was observed in the three consecutive years. In particular, it was of note that the prevalence of serotype 3 greatly increased, in contrast to the previous studies in which almost no serotype 3 rotaviruses were detected in the years 1983-8 in Thailand.

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Selected References

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