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Epidemiology and Infection logoLink to Epidemiology and Infection
. 1996 Jun;116(3):347–351. doi: 10.1017/s0950268800052675

Risk factors for recent toxoplasma infection in pregnant women in Naples.

W Buffolano 1, R E Gilbert 1, F J Holland 1, D Fratta 1, F Palumbo 1, A E Ades 1
PMCID: PMC2271422  PMID: 8666080

Abstract

Effective primary prevention of congenital toxoplasmosis requires up to date information on locally relevant risk factors for infection in pregnant women. In Naples, risk factors for toxoplasma infection were compared in recently infected women (as assessed by detection of specific IgM in serum) and susceptible, IgG negative women. Recent infection was strongly associated with frequency of consumption of cured pork and raw meat. Eating cured pork or raw meat at least once a month increased the risk of toxoplasma infection threefold. This simple study design for determining locally relevant sources of toxoplasma infection is the first report of cured pork as a risk factor for infection. Further research is required to determine cyst viability in cured pork products. Our findings suggest that in southern Italy, cured pork and raw meat should be avoided by susceptible pregnant women.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ades A. E. Methods for estimating the incidence of primary infection in pregnancy: a reappraisal of toxoplasmosis and cytomegalovirus data. Epidemiol Infect. 1992 Apr;108(2):367–375. doi: 10.1017/s0950268800049839. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Ades A. E., Nokes D. J. Modeling age- and time-specific incidence from seroprevalence:toxoplasmosis. Am J Epidemiol. 1993 May 1;137(9):1022–1034. doi: 10.1093/oxfordjournals.aje.a116758. [DOI] [PubMed] [Google Scholar]
  3. Bobić B., Sibalić D., Djurković-Djaković O. High levels of IgM antibodies specific for Toxoplasma gondii in pregnancy 12 years after primary toxoplasma infection. Case report. Gynecol Obstet Invest. 1991;31(3):182–184. doi: 10.1159/000293151. [DOI] [PubMed] [Google Scholar]
  4. Dubey J. P. Long-term persistence of Toxoplasma gondii in tissues of pigs inoculated with T gondii oocysts and effect of freezing on viability of tissue cysts in pork. Am J Vet Res. 1988 Jun;49(6):910–913. [PubMed] [Google Scholar]
  5. Dubey J. P., Thulliez P. Persistence of tissue cysts in edible tissues of cattle fed Toxoplasma gondii oocysts. Am J Vet Res. 1993 Feb;54(2):270–273. [PubMed] [Google Scholar]
  6. JACOBS L., REMINGTON J. S., MELTON M. L. The resistance of the encysted form of Toxoplasma gondii. J Parasitol. 1960 Feb;46:11–21. [PubMed] [Google Scholar]
  7. Lundén A., Uggla A. Infectivity of Toxoplasma gondii in mutton following curing, smoking, freezing or microwave cooking. Int J Food Microbiol. 1992 Mar-Apr;15(3-4):357–363. doi: 10.1016/0168-1605(92)90069-f. [DOI] [PubMed] [Google Scholar]
  8. Payne R. A., Joynson D. H., Balfour A. H., Harford J. P., Fleck D. G., Mythen M., Saunders R. J. Public Health Laboratory Service enzyme linked immunosorbent assay for detecting Toxoplasma specific IgM antibody. J Clin Pathol. 1987 Mar;40(3):276–281. doi: 10.1136/jcp.40.3.276. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Song C. C., Yuan X. Z., Shen L. Y., Gan X. X., Ding J. Z. The effect of cobalt-60 irradiation on the infectivity of Toxoplasma gondii. Int J Parasitol. 1993 Feb;23(1):89–93. doi: 10.1016/0020-7519(93)90101-4. [DOI] [PubMed] [Google Scholar]
  10. Wacholder S. Binomial regression in GLIM: estimating risk ratios and risk differences. Am J Epidemiol. 1986 Jan;123(1):174–184. doi: 10.1093/oxfordjournals.aje.a114212. [DOI] [PubMed] [Google Scholar]
  11. Wallace M. R., Rossetti R. J., Olson P. E. Cats and toxoplasmosis risk in HIV-infected adults. JAMA. 1993 Jan 6;269(1):76–77. [PubMed] [Google Scholar]
  12. Work K. Resistance of Toxoplasma gondii encysted in pork. Acta Pathol Microbiol Scand. 1968;73(1):85–92. doi: 10.1111/j.1699-0463.1968.tb00482.x. [DOI] [PubMed] [Google Scholar]

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