Skip to main content
Epidemiology and Infection logoLink to Epidemiology and Infection
. 1994 Feb;112(1):201–211. doi: 10.1017/s0950268800057575

Analysis of mixed foot-and-mouth disease virus infections in Saudi Arabia: prolonged circulation of an exotic serotype.

E L Woodbury 1, A R Samuel 1, N J Knowles 1, S M Hafez 1, R P Kitching 1
PMCID: PMC2271471  PMID: 8119359

Abstract

Plaque purification of foot-and-mouth disease (FMD) type O viruses isolated from cattle in Saudi Arabia showed the presence of mixed serotype infections. Sixteen out of 31 samples collected between 1985 and 1991 also contained Asia 1 virus, a serotype which had previously only been isolated from a single outbreak in that country in 1980. Nucleotide sequences of the Asia 1 component of all these samples revealed little variation and showed that they were closely related to both a Russian lapinized vaccine virus strain (Asia 1/Tadzhikistan/64), and to a field isolate from Turkey (Asia 1/TUR/15/73). Although mixed FMD infections have been observed previously this is a first report of a serotype, considered to be exotic to a country, co-existing undetected for an extended period of time.

Full text

PDF
204

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amaral-Doel C. M., Owen N. E., Ferris N. P., Kitching R. P., Doel T. R. Detection of foot-and-mouth disease viral sequences in clinical specimens and ethyleneimine-inactivated preparations by the polymerase chain reaction. Vaccine. 1993;11(4):415–421. doi: 10.1016/0264-410x(93)90281-2. [DOI] [PubMed] [Google Scholar]
  2. Ansell D. M., Samuel A. R., Carpenter W. C., Knowles N. J. Genetic relationships between foot-and-mouth disease type Asia 1 viruses. Epidemiol Infect. 1994 Feb;112(1):213–224. doi: 10.1017/s0950268800057587. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Arrowsmith A. E. Variation among strains of type A foot-and-mouth disease virus in the Eastern Mediterranean region 1964-1972. J Hyg (Lond) 1975 Dec;75(3):387–397. doi: 10.1017/s0022172400024451. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Brooksby J. R. Exotic strain of foot-and-mouth disease in Turkey. Vet Rec. 1973 Sep 15;93(11):320–321. doi: 10.1136/vr.93.11.320. [DOI] [PubMed] [Google Scholar]
  5. Hedger R. S. Foot-and-mouth disease and the African buffalo (Syncerus caffer). J Comp Pathol. 1972 Jan;82(1):19–28. doi: 10.1016/0021-9975(72)90022-9. [DOI] [PubMed] [Google Scholar]
  6. Kitching R. P., Rendle R., Ferris N. P. Rapid correlation between field isolates and vaccine strains of foot-and-mouth disease virus. Vaccine. 1988 Oct;6(5):403–408. doi: 10.1016/0264-410x(88)90139-9. [DOI] [PubMed] [Google Scholar]
  7. Kitson J. D., McCahon D., Belsham G. J. Sequence analysis of monoclonal antibody resistant mutants of type O foot and mouth disease virus: evidence for the involvement of the three surface exposed capsid proteins in four antigenic sites. Virology. 1990 Nov;179(1):26–34. doi: 10.1016/0042-6822(90)90269-w. [DOI] [PubMed] [Google Scholar]
  8. Krebs O., Marquardt O. Identification and characterization of foot-and-mouth disease virus O1 Burgwedel/1987 as an intertypic recombinant. J Gen Virol. 1992 Mar;73(Pt 3):613–619. doi: 10.1099/0022-1317-73-3-613. [DOI] [PubMed] [Google Scholar]
  9. Moosbrugger G. A. Les variations de type du virus aphteux en cours d'epizootie. Bull Off Int Epizoot. 1966 Nov-Dec;65(11):2023–2034. [PubMed] [Google Scholar]
  10. Roeder P. L., Le Blanc Smith P. M. Detection and typing of foot-and-mouth disease virus by enzyme-linked immunosorbent assay: a sensitive, rapid and reliable technique for primary diagnosis. Res Vet Sci. 1987 Sep;43(2):225–232. [PubMed] [Google Scholar]
  11. Samuel A. R., Knowles N. J., Kitching R. P. Serological and biochemical analysis of some recent type A foot-and-mouth disease virus isolates from the Middle East. Epidemiol Infect. 1988 Dec;101(3):577–590. doi: 10.1017/s0950268800029447. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Samuel A. R., Knowles N. J., Samuel G. D., Crowther J. R. Evaluation of a trapping ELISA for the differentiation of foot-and-mouth disease virus strains using monoclonal antibodies. Biologicals. 1991 Oct;19(4):299–310. doi: 10.1016/s1045-1056(05)80019-3. [DOI] [PubMed] [Google Scholar]
  13. Samuel A. R., Ouldridge E. J., Arrowsmith A. E., Kitching R. P., Knowles N. J. Antigenic analysis of serotype O foot-and-mouth disease virus isolates from the Middle East, 1981 to 1988. Vaccine. 1990 Aug;8(4):390–396. doi: 10.1016/0264-410x(90)90100-z. [DOI] [PubMed] [Google Scholar]
  14. Sanger F., Nicklen S., Coulson A. R. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463–5467. doi: 10.1073/pnas.74.12.5463. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Xie Q. C., McCahon D., Crowther J. R., Belsham G. J., McCullough K. C. Neutralization of foot-and-mouth disease virus can be mediated through any of at least three separate antigenic sites. J Gen Virol. 1987 Jun;68(Pt 6):1637–1647. doi: 10.1099/0022-1317-68-6-1637. [DOI] [PubMed] [Google Scholar]
  16. Zimmern D., Kaesberg P. 3'-terminal nucleotide sequence of encephalomyocarditis virus RNA determined by reverse transcriptase and chain-terminating inhibitors. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4257–4261. doi: 10.1073/pnas.75.9.4257. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Epidemiology and Infection are provided here courtesy of Cambridge University Press

RESOURCES