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. 1994 Feb;112(1):201–211. doi: 10.1017/s0950268800057575

Analysis of mixed foot-and-mouth disease virus infections in Saudi Arabia: prolonged circulation of an exotic serotype.

E L Woodbury 1, A R Samuel 1, N J Knowles 1, S M Hafez 1, R P Kitching 1
PMCID: PMC2271471  PMID: 8119359

Abstract

Plaque purification of foot-and-mouth disease (FMD) type O viruses isolated from cattle in Saudi Arabia showed the presence of mixed serotype infections. Sixteen out of 31 samples collected between 1985 and 1991 also contained Asia 1 virus, a serotype which had previously only been isolated from a single outbreak in that country in 1980. Nucleotide sequences of the Asia 1 component of all these samples revealed little variation and showed that they were closely related to both a Russian lapinized vaccine virus strain (Asia 1/Tadzhikistan/64), and to a field isolate from Turkey (Asia 1/TUR/15/73). Although mixed FMD infections have been observed previously this is a first report of a serotype, considered to be exotic to a country, co-existing undetected for an extended period of time.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amaral-Doel C. M., Owen N. E., Ferris N. P., Kitching R. P., Doel T. R. Detection of foot-and-mouth disease viral sequences in clinical specimens and ethyleneimine-inactivated preparations by the polymerase chain reaction. Vaccine. 1993;11(4):415–421. doi: 10.1016/0264-410x(93)90281-2. [DOI] [PubMed] [Google Scholar]
  2. Ansell D. M., Samuel A. R., Carpenter W. C., Knowles N. J. Genetic relationships between foot-and-mouth disease type Asia 1 viruses. Epidemiol Infect. 1994 Feb;112(1):213–224. doi: 10.1017/s0950268800057587. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Arrowsmith A. E. Variation among strains of type A foot-and-mouth disease virus in the Eastern Mediterranean region 1964-1972. J Hyg (Lond) 1975 Dec;75(3):387–397. doi: 10.1017/s0022172400024451. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Brooksby J. R. Exotic strain of foot-and-mouth disease in Turkey. Vet Rec. 1973 Sep 15;93(11):320–321. doi: 10.1136/vr.93.11.320. [DOI] [PubMed] [Google Scholar]
  5. Hedger R. S. Foot-and-mouth disease and the African buffalo (Syncerus caffer). J Comp Pathol. 1972 Jan;82(1):19–28. doi: 10.1016/0021-9975(72)90022-9. [DOI] [PubMed] [Google Scholar]
  6. Kitching R. P., Rendle R., Ferris N. P. Rapid correlation between field isolates and vaccine strains of foot-and-mouth disease virus. Vaccine. 1988 Oct;6(5):403–408. doi: 10.1016/0264-410x(88)90139-9. [DOI] [PubMed] [Google Scholar]
  7. Kitson J. D., McCahon D., Belsham G. J. Sequence analysis of monoclonal antibody resistant mutants of type O foot and mouth disease virus: evidence for the involvement of the three surface exposed capsid proteins in four antigenic sites. Virology. 1990 Nov;179(1):26–34. doi: 10.1016/0042-6822(90)90269-w. [DOI] [PubMed] [Google Scholar]
  8. Krebs O., Marquardt O. Identification and characterization of foot-and-mouth disease virus O1 Burgwedel/1987 as an intertypic recombinant. J Gen Virol. 1992 Mar;73(Pt 3):613–619. doi: 10.1099/0022-1317-73-3-613. [DOI] [PubMed] [Google Scholar]
  9. Moosbrugger G. A. Les variations de type du virus aphteux en cours d'epizootie. Bull Off Int Epizoot. 1966 Nov-Dec;65(11):2023–2034. [PubMed] [Google Scholar]
  10. Roeder P. L., Le Blanc Smith P. M. Detection and typing of foot-and-mouth disease virus by enzyme-linked immunosorbent assay: a sensitive, rapid and reliable technique for primary diagnosis. Res Vet Sci. 1987 Sep;43(2):225–232. [PubMed] [Google Scholar]
  11. Samuel A. R., Knowles N. J., Kitching R. P. Serological and biochemical analysis of some recent type A foot-and-mouth disease virus isolates from the Middle East. Epidemiol Infect. 1988 Dec;101(3):577–590. doi: 10.1017/s0950268800029447. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Samuel A. R., Knowles N. J., Samuel G. D., Crowther J. R. Evaluation of a trapping ELISA for the differentiation of foot-and-mouth disease virus strains using monoclonal antibodies. Biologicals. 1991 Oct;19(4):299–310. doi: 10.1016/s1045-1056(05)80019-3. [DOI] [PubMed] [Google Scholar]
  13. Samuel A. R., Ouldridge E. J., Arrowsmith A. E., Kitching R. P., Knowles N. J. Antigenic analysis of serotype O foot-and-mouth disease virus isolates from the Middle East, 1981 to 1988. Vaccine. 1990 Aug;8(4):390–396. doi: 10.1016/0264-410x(90)90100-z. [DOI] [PubMed] [Google Scholar]
  14. Sanger F., Nicklen S., Coulson A. R. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463–5467. doi: 10.1073/pnas.74.12.5463. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Xie Q. C., McCahon D., Crowther J. R., Belsham G. J., McCullough K. C. Neutralization of foot-and-mouth disease virus can be mediated through any of at least three separate antigenic sites. J Gen Virol. 1987 Jun;68(Pt 6):1637–1647. doi: 10.1099/0022-1317-68-6-1637. [DOI] [PubMed] [Google Scholar]
  16. Zimmern D., Kaesberg P. 3'-terminal nucleotide sequence of encephalomyocarditis virus RNA determined by reverse transcriptase and chain-terminating inhibitors. Proc Natl Acad Sci U S A. 1978 Sep;75(9):4257–4261. doi: 10.1073/pnas.75.9.4257. [DOI] [PMC free article] [PubMed] [Google Scholar]

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