Abstract
A multidrug resistant (MDR) variety of Salmonella typhi emerged as the cause of epidemic typhoid fever in some Asian countries including India, during the late 1980s. We faced the epidemic from April 1990 to the first quarter of 1993. However, during this period we continued to isolate chloramphenicol sensitive (CS) S. typhi also. The relative prevalences showed that the frequency of CS variety was unaffected by the epidemic of MDR variety. This is an unusual epidemiological pattern, which indicates that there may have been factors which favoured the epidemic of the MDR variety but not the CS one.
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- Bauer A. W., Kirby W. M., Sherris J. C., Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966 Apr;45(4):493–496. [PubMed] [Google Scholar]
- Goldstein F. W., Chumpitaz J. C., Guevara J. M., Papadopoulou B., Acar J. F., Vieu J. F. Plasmid-mediated resistance to multiple antibiotics in Salmonella typhi. J Infect Dis. 1986 Feb;153(2):261–266. doi: 10.1093/infdis/153.2.261. [DOI] [PubMed] [Google Scholar]
- Jesudason M. V., John T. J. The appearance & spread of Vibrio cholerae 0139 in India. Indian J Med Res. 1994 Mar;99:97–100. [PubMed] [Google Scholar]
- Koshi G., Alex W., Menon T. An improved technique for blood culture. Indian J Med Res. 1981 May;73:733–738. [PubMed] [Google Scholar]
- Ramanan A., Pandit N., Yeshwanth M. Unusual complications in a multidrug resistant Salmonella typhi outbreak. Indian Pediatr. 1992 Jan;29(1):118–120. [PubMed] [Google Scholar]
- Sharma A., Gathwala G. Clinical profile and outcome in enteric fever. Indian Pediatr. 1993 Jan;30(1):47–50. [PubMed] [Google Scholar]
- Threlfall E. J., Ward L. R., Rowe B., Raghupathi S., Chandrasekaran V., Vandepitte J., Lemmens P. Widespread occurrence of multiple drug-resistant Salmonella typhi in India. Eur J Clin Microbiol Infect Dis. 1992 Nov;11(11):990–993. doi: 10.1007/BF01967788. [DOI] [PubMed] [Google Scholar]
- Wang F., Gu X. J., Zhang M. F., Tai T. Y. Treatment of typhoid fever with ofloxacin. J Antimicrob Chemother. 1989 May;23(5):785–788. doi: 10.1093/jac/23.5.785. [DOI] [PubMed] [Google Scholar]