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. 1990 Apr;104(2):203–209. doi: 10.1017/s0950268800059367

Secretor status, smoking and carriage of Neisseria meningitidis.

C C Blackwell 1, D M Weir 1, V S James 1, W T Todd 1, N Banatvala 1, A K Chaudhuri 1, H G Gray 1, E J Thomson 1, R J Fallon 1
PMCID: PMC2271764  PMID: 2323355

Abstract

A survey of ABO blood groups, secretor status and smoking habits among 389 students and staff of a school in which there was an outbreak of meningococcal disease found no difference in the distribution of the ABO blood groups but a significantly higher proportion of non-secretors (37.6%) in the population examined compared with that reported for previous surveys of the neighbouring population in Glasgow (26.2%) (P less than 0.0005). There was also a significantly higher proportion of non-secretors among carriers of meningococci (47%) compared with non-carriers (32%). Increased carriage of meningococci among non-secretors might contribute to the increased susceptibility of individuals with this genetic characteristic to meningococcal disease observed in previous studies. Although passive exposure to cigarette smoke has been associated with meningococcal disease, there was no association between passive smoking and carriage. There was, however, a significant association between active smoking and carriage.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Blackwell C. C., Jónsdóttir K., Hanson M., Todd W. T., Chaudhuri A. K., Mathew B., Brettle R. P., Weir D. M. Non-secretion of ABO antigens predisposing to infection by Neisseria meningitidis and Streptococcus pneumoniae. Lancet. 1986 Aug 2;2(8501):284–285. doi: 10.1016/s0140-6736(86)92103-3. [DOI] [PubMed] [Google Scholar]
  2. Blackwell C. C., Weir D. M., James V. S., Cartwright K. A., Stuart J. M., Jones D. M. The Stonehouse study: secretor status and carriage of Neisseria species. Epidemiol Infect. 1989 Feb;102(1):1–10. doi: 10.1017/s0950268800029629. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Burford-Mason A. P., Weber J. C., Willoughby J. M. Oral carriage of Candida albicans, ABO blood group and secretor status in healthy subjects. J Med Vet Mycol. 1988 Feb;26(1):49–56. doi: 10.1080/02681218880000061. [DOI] [PubMed] [Google Scholar]
  4. CAMERON J. M. Blood-groups in tumours of salivary tissue. Lancet. 1958 Feb 1;1(7014):239–240. doi: 10.1016/s0140-6736(58)90921-8. [DOI] [PubMed] [Google Scholar]
  5. Cartwright K. A., Stuart J. M., Jones D. M., Noah N. D. The Stonehouse survey: nasopharyngeal carriage of meningococci and Neisseria lactamica. Epidemiol Infect. 1987 Dec;99(3):591–601. doi: 10.1017/s0950268800066449. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. EICHENWALD H. F., KOTSEVALOV O., FASSO L. A. Some effects of viral infection on aerial dissemination of staphylococci and on susceptibility to bacterial colonization. Bacteriol Rev. 1961 Sep;25:274–281. doi: 10.1128/br.25.3.274-281.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Editorial: Straining, sitting, and squatting at stool. Lancet. 1975 Jul 5;2(7923):18–19. [PubMed] [Google Scholar]
  8. Haneberg B., Tønjum T., Rodahl K., Gedde-Dahl T. W. Factors preceding the onset of meningococcal disease, with special emphasis on passive smoking, symptoms of ill health. NIPH Ann. 1983 Dec;6(2):169–173. [PubMed] [Google Scholar]
  9. Haverkorn M. J., Goslings W. R. Streptococci, ABO blood groups, and secretor status. Am J Hum Genet. 1969 Jul;21(4):360–375. [PMC free article] [PubMed] [Google Scholar]
  10. Kaiser A. B., Hennekens C. H., Saslaw M. S., Hayes P. S., Bennett J. V. Seroepidemiology and chemoprophylaxis disease due to sulfonamide-resistant Neisseria meningitidis in a civillian population. J Infect Dis. 1974 Sep;130(3):217–224. doi: 10.1093/infdis/130.3.217. [DOI] [PubMed] [Google Scholar]
  11. Kinane D. F., Blackwell C. C., Brettle R. P., Weir D. M., Winstanley F. P., Elton R. A. ABO blood group, secretor state, and susceptibility to recurrent urinary tract infection in women. Br Med J (Clin Res Ed) 1982 Jul 3;285(6334):7–9. doi: 10.1136/bmj.285.6334.7. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Krasinski K., Nelson J. D., Butler S., Luby J. P., Kusmiesz H. Possible association of mycoplasma and viral respiratory infections with bacterial meningitis. Am J Epidemiol. 1987 Mar;125(3):499–508. doi: 10.1093/oxfordjournals.aje.a114556. [DOI] [PubMed] [Google Scholar]
  13. MACSWEEN M. P., SYME U. A. ABO BLOOD GROUPS AND SKIN DISEASES. Br J Dermatol. 1965 Jan;77:30–34. doi: 10.1111/j.1365-2133.1965.tb14563.x. [DOI] [PubMed] [Google Scholar]
  14. Nichol K. P., Cherry J. D. Bacterial-viral interrelations in respiratory infections of children. N Engl J Med. 1967 Sep 28;277(13):667–672. doi: 10.1056/NEJM196709282771301. [DOI] [PubMed] [Google Scholar]
  15. Stuart J. M., Cartwright K. A., Dawson J. A., Rickard J., Noah N. D. Risk factors for meningococcal disease: a case control study in south west England. Community Med. 1988 May;10(2):139–146. [PubMed] [Google Scholar]
  16. Stuart J. M., Cartwright K. A., Jones D. M., Noah N. D., Wall R. J., Blackwell C. C., Jephcott A. E., Ferguson I. R. An outbreak of meningococcal disease in Stonehouse: planning and execution of a large-scale survey. Epidemiol Infect. 1987 Dec;99(3):579–589. doi: 10.1017/s0950268800066437. [DOI] [PMC free article] [PubMed] [Google Scholar]

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