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. 1992 Apr;108(2):353–365. doi: 10.1017/s0950268800049827

Antigenic and genetic analyses of eight influenza C strains isolated in various areas of Japan during 1985-9.

S Ohyama 1, K Adachi 1, K Sugawara 1, S Hongo 1, H Nishimura 1, F Kitame 1, K Nakamura 1
PMCID: PMC2271984  PMID: 1374720

Abstract

Eight strains of influenza C virus isolated in various areas of Japan between January 1985 and January 1989 were compared using monoclonal antibodies to the haemagglutinin-esterase (HE) glycoproteins and by oligonucleotide mapping of total vRNA. Five of six strains isolated during 1986-9 were closely related to one another and also resembled the virus, C/Aichi/1/81, isolated in 1981 in Aichi prefecture. This suggests that the C/Aichi/1/81-related viruses had an epidemiological advantage over any co-circulating viruses at least during that period. One of two 1985 isolates (C/Nara/1/85) was antigenically indistinguishable from the C/Mississippi/1/80 strain though their oligonucleotide patterns were markedly different from each other. This raises the possibility that C/Nara/1/85 may be a recombinant virus which receives its HE gene from the C/Mississippi/1/80-related parent.

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Selected References

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