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. 1976 Jan;125(1):33–41. doi: 10.1128/jb.125.1.33-41.1976

Genetic co-regulation of galactose and melibiose utilization in Saccharomyces.

O M Kew, H C Douglas
PMCID: PMC233332  PMID: 1245460

Abstract

The gal3 mutation of Saccharomyces, which is associated with an impairment in the utilization of galactose, has been shown to be pleiotropic, causing similar impairments in the utilization of melibiose and maltose. Milibiose utilization and alpha-galactosidase production are directly controlled by the galactose regulatory elements i, c, and GAL4. The fermentation of maltose and the induction of alpha-glucosidase are regulated independently of the i, c, GAL4 system. The production of alpha-galactosidase and galactose-1-phosphate uridyl transferase is coordinate in galactokinaseless strains. Galactose serves as a nonmetabolized, gratuitous inducer of alpha-galactosidase in strains lacking the genes for one or more of the Leloir pathway enzymes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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