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. 1976 Jan;125(1):346–352. doi: 10.1128/jb.125.1.346-352.1976

Direction of deoxyribonucleic acid replication in Escherichia coli under various conditions of cell growth.

R L Rodriguez, C I Davern
PMCID: PMC233369  PMID: 1107310

Abstract

The direction of chromosome replication in a temperature-sensitive initiation mutant of Escherichia coli (CT28) is shown autoradiographically to be bidirectional. This mode of replication persists even when the rate of replication is reduced by slow growth in succinate minimal medium or in the presence of chloramphenicol. Therefore, although the rate of replication can be affected by certain physiological stimuli, the topology of replication need not be.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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