Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1977 Sep;131(3):1033–1036. doi: 10.1128/jb.131.3.1033-1036.1977

Fine-structure mapping of the firA gene, a locus involved in the phenotypic expression of rifampin resistance in Escherichia.

R Lathe
PMCID: PMC235568  PMID: 330494

Abstract

The firA (Ts)200 mutation not only eliminates the resistance to rifampin of certain genetically resistant strains, but, moreover, renders ribonucleic acid synthesis thermolabile. The firA gene has been mapped by P1 tranduction and is located extremely close to the structural gene for deoxyribonucleic acid polymerase III at 4 min on the Escherichia coli linkage map.

Full text

PDF
1036

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bukhari A. I., Taylor A. L. Genetic analysis of diaminopimelic acid- and lysine-requiring mutants of Escherichia coli. J Bacteriol. 1971 Mar;105(3):844–854. doi: 10.1128/jb.105.3.844-854.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Cooper S. Utilization of d-Methionine by Escherichia coli. J Bacteriol. 1966 Aug;92(2):328–332. doi: 10.1128/jb.92.2.328-332.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Friesen J. D., Parker J., Watson R. J., Bendiak D., Reeh S. V., Pedersen S., Fiil N. P. A transducing bacteriophage lambda carrying the structural gene for elongation factor Ts. Mol Gen Genet. 1976 Oct 18;148(1):93–98. doi: 10.1007/BF00268549. [DOI] [PubMed] [Google Scholar]
  4. Hayward R. S., Scaife J. G. Systematic nomenclature for the RNA polymerase genes of prokaryotes. Nature. 1976 Apr 15;260(5552):646–648. doi: 10.1038/260646a0. [DOI] [PubMed] [Google Scholar]
  5. Patterson D., Weinstein M., Marshall S., Gillespie D. A new RNA synthesis mutant of E. coli. Biochem Genet. 1971 Dec;5(6):563–578. doi: 10.1007/BF00485674. [DOI] [PubMed] [Google Scholar]
  6. Powell K. A., Cox R., McConville M., Charles H. P. Mutations affecting porphyrin biosynthesis in Escherichia coli. Enzyme. 1973;16(1):65–73. doi: 10.1159/000459363. [DOI] [PubMed] [Google Scholar]
  7. Rabussay D., Zillig W. A rifampicin resistent rna-polymerase from E. coli altered in the beta-subunit. FEBS Lett. 1969 Oct 21;5(2):104–106. doi: 10.1016/0014-5793(69)80305-4. [DOI] [PubMed] [Google Scholar]
  8. Srivastava R., Toussaint C., Lecocoq J. P. A rifampicin-resistant mutation of E. coli, whose phenotypic expression is dependent on the composition of the medium and the recA allele. Mutat Res. 1974 Apr;23(1):25–28. doi: 10.1016/0027-5107(74)90156-0. [DOI] [PubMed] [Google Scholar]
  9. Taylor R. G. Non-Malignant Lesions of the Colon-Their Roentgenological Diagnosis. Cal West Med. 1934 Jan;40(1):11–14. [PMC free article] [PubMed] [Google Scholar]
  10. Wechsler J. A., Gross J. D. Escherichia coli mutants temperature-sensitive for DNA synthesis. Mol Gen Genet. 1971;113(3):273–284. doi: 10.1007/BF00339547. [DOI] [PubMed] [Google Scholar]
  11. Wu T. T. A model for three-point analysis of random general transduction. Genetics. 1966 Aug;54(2):405–410. doi: 10.1093/genetics/54.2.405. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Yamamoto M., Strycharz W. A., Nomura M. Identification of genes for elongation factor Ts and ribosomal protein S2 in E. coli. Cell. 1976 May;8(1):129–138. doi: 10.1016/0092-8674(76)90194-x. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES