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. 1975 Dec;124(3):1148–1152. doi: 10.1128/jb.124.3.1148-1152.1975

Phospholipase D activity of gram-negative bacteria.

R Cole, P Proulx
PMCID: PMC236020  PMID: 360

Abstract

A phospholipase hydrolyzing cardiolipin to phosphatidic acid and phosphatidyl glycerol was characterized in gram-negative bacteria but was absent in preparations of gram-positive bacteria, Saccharomyces cerevisiae, and rat liver mitochondria. In cell-free extracts of Escherichia coli, Salmonella typhimurium, Proteus vulgaris, and Pseudomonase aeruginosa, this cardiolipin-hydrolyzing enzyme had similar pH and Mg2+ requirements and displayed a specificity which excluded phosphatidyl glycerol and phosphatidyl ethanolamine as substrates.

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Selected References

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