Skip to main content
PMC home page
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1976 Feb;125(2):689–697. doi: 10.1128/jb.125.2.689-697.1976

Uric acid degradation by Bacillus fastidiosus strains.

G P Bongaerts, G D Vogels
PMCID: PMC236130  PMID: 1245468

Abstract

Seven Bacillus strains including one of the original Bacillus fastidiosus strains of Den Dooren de Jong could grow on urate, allantoin, and, except one, on allantoate. No growth could be detected on adenine, guanine, hypoxanthine, xanthine, and on degradation products of allantoate. Some strains grew very slowly in complex media. The metabolic pathway from urate to glyoxylate involved uricase, S(+)-allantoinase, allantoate amidohydrolase, S(-)-ureidoglycolase, and, in some strains, urease.

Full text

PDF
697

Images in this article

692Image
on p.692

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERGMANN F., DIKSTEIN S., HENIS Y. Studies on uric acid and related compounds. IV. The specificity of bacterial xanthine oxidases. J Biol Chem. 1957 Jan;224(1):67–77. [PubMed] [Google Scholar]
  2. DETURK W. E. The adaptive formation of urease by washed suspensions of Pseudomonas aeruginosa. J Bacteriol. 1955 Aug;70(2):187–191. doi: 10.1128/jb.70.2.187-191.1955. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Franke W., Thiemann A., Remily C., Möchel L., Heye K. Zur Kenntnis ureidspaltender Enzyme. I. Soja-Allantoinase. Enzymologia. 1965 Nov 6;29(3):251–271. [PubMed] [Google Scholar]
  4. Friedman T. B., Merrill C. R. A microradiochemical assay for urate oxidase. Anal Biochem. 1973 Sep;55(1):292–296. doi: 10.1016/0003-2697(73)90317-5. [DOI] [PubMed] [Google Scholar]
  5. Gravenmade E. J., Vogels G. D., Van der Drift C. Hydrolysis, racemization and absolute configuration of ureidoglycolate, a substrate of allantoicase. Biochim Biophys Acta. 1970 Mar 18;198(3):569–582. doi: 10.1016/0005-2744(70)90134-8. [DOI] [PubMed] [Google Scholar]
  6. Holt S. C., Leadbetter E. R. Comparative ultrastructure of selected aerobic spore-forming bacteria: a freeze-etching study. Bacteriol Rev. 1969 Jun;33(2):346–378. doi: 10.1128/br.33.2.346-378.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Kaltwasser H. Studies on the physiology of Bacillus fastidiosus. J Bacteriol. 1971 Sep;107(3):780–786. doi: 10.1128/jb.107.3.780-786.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. König C., Kaltwasser H., Schlegel H. G. DIE Bildung von Urease nach Verbrauch der äusseren N-Quelle bei Hydrogenomonas H16. Arch Mikrobiol. 1966 Mar 31;53(3):231–241. [PubMed] [Google Scholar]
  9. Mahler J. L. A new bacterial uricase for uric acid determination. Anal Biochem. 1970 Nov;38(1):65–84. doi: 10.1016/0003-2697(70)90156-9. [DOI] [PubMed] [Google Scholar]
  10. Richard C. Mesure de l'activité uréasique des Proteus au moyen de la réaction phénol-hypochlorite de Berthelot. Intérêt taxinomique. Ann Inst Pasteur (Paris) 1965 Oct;109(4):516–524. [PubMed] [Google Scholar]
  11. Rouf M. A., Lomprey R. F., Jr Degradation of uric acid by certain aerobic bacteria. J Bacteriol. 1968 Sep;96(3):617–622. doi: 10.1128/jb.96.3.617-622.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Trijbels F., Vogels G. D. Degradation of allantoin by Pseudomonas acidovorans. Biochim Biophys Acta. 1966 Feb 14;113(2):292–301. doi: 10.1016/s0926-6593(66)80068-1. [DOI] [PubMed] [Google Scholar]
  13. Truszkowski R. Uricase and its action: Bacterial nature of the action of uricolytic extracts and dialysates. Biochem J. 1930;24(5):1340–1348. doi: 10.1042/bj0241340. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Vogels G. D. Reversible activation of allantoate amidohydrolase by acid-pretreatment and other properties of the enzyme. Biochim Biophys Acta. 1966 Feb 14;113(2):277–291. doi: 10.1016/s0926-6593(66)80067-x. [DOI] [PubMed] [Google Scholar]
  15. Vogels G. D. Stereospecificity in the allantoin metabolism. Antonie Van Leeuwenhoek. 1969;35(2):236–238. doi: 10.1007/BF02219137. [DOI] [PubMed] [Google Scholar]
  16. Vogels G. D., Van der Drift C. Differential analyses of glyoxylate derivatives. Anal Biochem. 1970 Jan;33(1):143–157. doi: 10.1016/0003-2697(70)90448-3. [DOI] [PubMed] [Google Scholar]
  17. WHITELEY H. R., DOUGLAS H. C. The fermentation of purines by Micrococcus lactilyticus. J Bacteriol. 1951 May;61(5):605–616. doi: 10.1128/jb.61.5.605-616.1951. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Watt W. B. Xanthine dehydrogenase and pteridine metabolism in Colias butterflies. J Biol Chem. 1972 Mar 10;247(5):1445–1451. [PubMed] [Google Scholar]
  19. van der Drift C., Vogels G. D. Allantoate amidohydrolase. I. pH- and anion-dependent activation. Enzymologia. 1969;36(4):269–277. [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES