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. 1994 Aug;68(8):5326–5329. doi: 10.1128/jvi.68.8.5326-5329.1994

Induction of G protein-coupled peptide receptor EBI 1 by human herpesvirus 6 and 7 infection in CD4+ T cells.

H Hasegawa 1, Y Utsunomiya 1, M Yasukawa 1, K Yanagisawa 1, S Fujita 1
PMCID: PMC236483  PMID: 7913511

Abstract

EBI 1, a putative lymphocyte-specific G protein-coupled peptide receptor, was induced by human herpesvirus 6 or 7 infection in CD4+ T cells, and its expression increased early after infection and reached a plateau at 48 h. The induction of the EBI 1 gene by human herpesvirus 6 or 7 infection was not mediated by soluble factors but by the virus itself. Deduced from comparisons of the amino acid sequences among members of the G protein-coupled receptor superfamily, these findings suggest that EBI 1 may be a member of the leukocyte chemotactic peptide receptor family.

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Selected References

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