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. 1994 Sep;68(9):6057–6058. doi: 10.1128/jvi.68.9.6057-6058.1994

Cell culture adaptation of astrovirus involves a deletion.

M M Willcocks 1, N Ashton 1, J B Kurtz 1, W D Cubitt 1, M J Carter 1
PMCID: PMC237012  PMID: 8057481

Abstract

Astroviruses have been adapted to culture by serial blind passage in primary human embryo cells. All viruses thus adapted possess a 45-nucleotide deletion relative to fecal viruses or isolates made in CaCo-2 cells; this deletion may be responsible for the change in host cell range.

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Selected References

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