Abstract
The bacterial virus f2 was inactivated by chlorine dioxide at acidic, neutral, and alkaline pH values. The rate of inactivation increased with increasing pH. Chlorine dioxide disproportionation products, chlorite and chlorate, were not active disinfectants. As chlorine dioxide solutions were degraded under alkaline conditions, they displayed reduced viricidal effectiveness, thereby confirming the chlorine dioxide free radical as the active disinfecting species.
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Selected References
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- Abdel-Rahman M. S., Couri D., Jones J. D. Chlorine dioxide metabolism in rat. J Environ Pathol Toxicol. 1979 Dec;3(1-2):421–430. [PubMed] [Google Scholar]
- Alvarez M. E., O'Brien R. T. Mechanisms of inactivation of poliovirus by chlorine dioxide and iodine. Appl Environ Microbiol. 1982 Nov;44(5):1064–1071. doi: 10.1128/aem.44.5.1064-1071.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bercz J. P., Jones L., Garner L., Murray D., Ludwig D. A., Boston J. Subchronic toxicity of chlorine dioxide and related compounds in drinking water in the nonhuman primate. Environ Health Perspect. 1982 Dec;46:47–55. doi: 10.1289/ehp.824647. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HARRISON B. L., ROSENBLATT D. H. PAPER PARTITION CHROMATOGRAPHY OF MIXTURES OF CHLORIDE, CHLORITE, CHLORATE AND PERCHLORATE. J Chromatogr. 1964 Jan;13:271–272. doi: 10.1016/s0021-9673(01)95114-3. [DOI] [PubMed] [Google Scholar]
- Heffernan W. P., Guion C., Bull R. J. Oxidative damage to the erythrocyte induced by sodium chlorite, in vivo. J Environ Pathol Toxicol. 1979 Jul-Aug;2(6):1487–1499. [PubMed] [Google Scholar]
- LOEB T., ZINDER N. D. A bacteriophage containing RNA. Proc Natl Acad Sci U S A. 1961 Mar 15;47:282–289. doi: 10.1073/pnas.47.3.282. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Yamamoto K. R., Alberts B. M., Benzinger R., Lawhorne L., Treiber G. Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large-scale virus purification. Virology. 1970 Mar;40(3):734–744. doi: 10.1016/0042-6822(70)90218-7. [DOI] [PubMed] [Google Scholar]