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. 1995 Sep;59(3):345–386. doi: 10.1128/mr.59.3.345-386.1995

Molecular basis of cell integrity and morphogenesis in Saccharomyces cerevisiae.

V J Cid 1, A Durán 1, F del Rey 1, M P Snyder 1, C Nombela 1, M Sánchez 1
PMCID: PMC239365  PMID: 7565410

Abstract

In fungi and many other organisms, a thick outer cell wall is responsible for determining the shape of the cell and for maintaining its integrity. The budding yeast Saccharomyces cerevisiae has been a useful model organism for the study of cell wall synthesis, and over the past few decades, many aspects of the composition, structure, and enzymology of the cell wall have been elucidated. The cell wall of budding yeasts is a complex and dynamic structure; its arrangement alters as the cell grows, and its composition changes in response to different environmental conditions and at different times during the yeast life cycle. In the past few years, we have witnessed a profilic genetic and molecular characterization of some key aspects of cell wall polymer synthesis and hydrolysis in the budding yeast. Furthermore, this organism has been the target of numerous recent studies on the topic of morphogenesis, which have had an enormous impact on our understanding of the intracellular events that participate in directed cell wall synthesis. A number of components that direct polarized secretion, including those involved in assembly and organization of the actin cytoskeleton, secretory pathways, and a series of novel signal transduction systems and regulatory components have been identified. Analysis of these different components has suggested pathways by which polarized secretion is directed and controlled. Our aim is to offer an overall view of the current understanding of cell wall dynamics and of the complex network that controls polarized growth at particular stages of the budding yeast cell cycle and life cycle.

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Selected References

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  1. Adams A. E., Botstein D., Drubin D. G. Requirement of yeast fimbrin for actin organization and morphogenesis in vivo. Nature. 1991 Dec 5;354(6352):404–408. doi: 10.1038/354404a0. [DOI] [PubMed] [Google Scholar]
  2. Adams A. E., Cooper J. A., Drubin D. G. Unexpected combinations of null mutations in genes encoding the actin cytoskeleton are lethal in yeast. Mol Biol Cell. 1993 May;4(5):459–468. doi: 10.1091/mbc.4.5.459. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Adams A. E., Johnson D. I., Longnecker R. M., Sloat B. F., Pringle J. R. CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae. J Cell Biol. 1990 Jul;111(1):131–142. doi: 10.1083/jcb.111.1.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Adams A. E., Pringle J. R. Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic-mutant Saccharomyces cerevisiae. J Cell Biol. 1984 Mar;98(3):934–945. doi: 10.1083/jcb.98.3.934. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Amatruda J. F., Cannon J. F., Tatchell K., Hug C., Cooper J. A. Disruption of the actin cytoskeleton in yeast capping protein mutants. Nature. 1990 Mar 22;344(6264):352–354. doi: 10.1038/344352a0. [DOI] [PubMed] [Google Scholar]
  6. Amatruda J. F., Cooper J. A. Purification, characterization, and immunofluorescence localization of Saccharomyces cerevisiae capping protein. J Cell Biol. 1992 Jun;117(5):1067–1076. doi: 10.1083/jcb.117.5.1067. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Amatruda J. F., Gattermeir D. J., Karpova T. S., Cooper J. A. Effects of null mutations and overexpression of capping protein on morphogenesis, actin distribution and polarized secretion in yeast. J Cell Biol. 1992 Dec;119(5):1151–1162. doi: 10.1083/jcb.119.5.1151. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Antonsson B., Montessuit S., Friedli L., Payton M. A., Paravicini G. Protein kinase C in yeast. Characteristics of the Saccharomyces cerevisiae PKC1 gene product. J Biol Chem. 1994 Jun 17;269(24):16821–16828. [PubMed] [Google Scholar]
  9. Appeltauer U., Achstetter T. Hormone-induced expression of the CHS1 gene from Saccharomyces cerevisiae. Eur J Biochem. 1989 Apr 15;181(1):243–247. doi: 10.1111/j.1432-1033.1989.tb14718.x. [DOI] [PubMed] [Google Scholar]
  10. Au-Young J., Robbins P. W. Isolation of a chitin synthase gene (CHS1) from Candida albicans by expression in Saccharomyces cerevisiae. Mol Microbiol. 1990 Feb;4(2):197–207. doi: 10.1111/j.1365-2958.1990.tb00587.x. [DOI] [PubMed] [Google Scholar]
  11. Baba M., Baba N., Ohsumi Y., Kanaya K., Osumi M. Three-dimensional analysis of morphogenesis induced by mating pheromone alpha factor in Saccharomyces cerevisiae. J Cell Sci. 1989 Oct;94(Pt 2):207–216. doi: 10.1242/jcs.94.2.207. [DOI] [PubMed] [Google Scholar]
  12. Bacon J. S., Farmer V. C., Jones D., Taylor I. F. The glucan components of the cell wall of baker's yeast (Saccharomyces cerevisiae) considered in relation to its ultrastructure. Biochem J. 1969 Sep;114(3):557–567. doi: 10.1042/bj1140557. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Baguley B. C., Römmele G., Gruner J., Wehrli W. Papulacandin B: an inhibitor of glucan synthesis in yeast spheroplasts. Eur J Biochem. 1979 Jul;97(2):345–351. doi: 10.1111/j.1432-1033.1979.tb13120.x. [DOI] [PubMed] [Google Scholar]
  14. Ballou C. E. Isolation, characterization, and properties of Saccharomyces cerevisiae mnn mutants with nonconditional protein glycosylation defects. Methods Enzymol. 1990;185:440–470. doi: 10.1016/0076-6879(90)85038-p. [DOI] [PubMed] [Google Scholar]
  15. Ballou C. E., Maitra S. K., Walker J. W., Whelan W. L. Developmental defects associated with glucosamine auxotrophy in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1977 Oct;74(10):4351–4355. doi: 10.1073/pnas.74.10.4351. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Ballou C. Structure and biosynthesis of the mannan component of the yeast cell envelope. Adv Microb Physiol. 1976;14(11):93–158. doi: 10.1016/s0065-2911(08)60227-1. [DOI] [PubMed] [Google Scholar]
  17. Barral Y., Jentsch S., Mann C. G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast. Genes Dev. 1995 Feb 15;9(4):399–409. doi: 10.1101/gad.9.4.399. [DOI] [PubMed] [Google Scholar]
  18. Basco R. D., Giménez-Gallego G., Larriba G. Processing of yeast exoglucanase (beta-glucosidase) in a KEX2-dependent manner. FEBS Lett. 1990 Jul 30;268(1):99–102. doi: 10.1016/0014-5793(90)80982-o. [DOI] [PubMed] [Google Scholar]
  19. Bauer F., Urdaci M., Aigle M., Crouzet M. Alteration of a yeast SH3 protein leads to conditional viability with defects in cytoskeletal and budding patterns. Mol Cell Biol. 1993 Aug;13(8):5070–5084. doi: 10.1128/mcb.13.8.5070. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Bender A., Pringle J. R. A Ser/Thr-rich multicopy suppressor of a cdc24 bud emergence defect. Yeast. 1992 Apr;8(4):315–323. doi: 10.1002/yea.320080409. [DOI] [PubMed] [Google Scholar]
  21. Bender A., Pringle J. R. Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9976–9980. doi: 10.1073/pnas.86.24.9976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Bender A., Pringle J. R. Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae. Mol Cell Biol. 1991 Mar;11(3):1295–1305. doi: 10.1128/mcb.11.3.1295. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Benton B. K., Tinkelenberg A. H., Jean D., Plump S. D., Cross F. R. Genetic analysis of Cln/Cdc28 regulation of cell morphogenesis in budding yeast. EMBO J. 1993 Dec 15;12(13):5267–5275. doi: 10.1002/j.1460-2075.1993.tb06222.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Biely P. Changes in the rate of synthesis of wall polysaccharides during the cell cycle of yeast. Arch Microbiol. 1978 Nov 13;119(2):213–214. doi: 10.1007/BF00964275. [DOI] [PubMed] [Google Scholar]
  25. Biely P., Krátký Z., Bauer S. Interaction of concanavalin A with external mannan-proteins of Saccharomyces cerevisiae. Glycoprotein nature of beta-glucanases. Eur J Biochem. 1976 Nov 1;70(1):75–81. doi: 10.1111/j.1432-1033.1976.tb10957.x. [DOI] [PubMed] [Google Scholar]
  26. Blacketer M. J., Koehler C. M., Coats S. G., Myers A. M., Madaule P. Regulation of dimorphism in Saccharomyces cerevisiae: involvement of the novel protein kinase homolog Elm1p and protein phosphatase 2A. Mol Cell Biol. 1993 Sep;13(9):5567–5581. doi: 10.1128/mcb.13.9.5567. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Blagoeva J., Stoev G., Venkov P. Glucan structure in a fragile mutant of Saccharomyces cerevisiae. Yeast. 1991 Jul;7(5):455–461. doi: 10.1002/yea.320070504. [DOI] [PubMed] [Google Scholar]
  28. Blomberg A., Adler L. Roles of glycerol and glycerol-3-phosphate dehydrogenase (NAD+) in acquired osmotolerance of Saccharomyces cerevisiae. J Bacteriol. 1989 Feb;171(2):1087–1092. doi: 10.1128/jb.171.2.1087-1092.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Boguslawski G. PBS2, a yeast gene encoding a putative protein kinase, interacts with the RAS2 pathway and affects osmotic sensitivity of Saccharomyces cerevisiae. J Gen Microbiol. 1992 Nov;138(11):2425–2432. doi: 10.1099/00221287-138-11-2425. [DOI] [PubMed] [Google Scholar]
  30. Boguslawski G., Polazzi J. O. Complete nucleotide sequence of a gene conferring polymyxin B resistance on yeast: similarity of the predicted polypeptide to protein kinases. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5848–5852. doi: 10.1073/pnas.84.16.5848. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Boone C., Sdicu A., Laroche M., Bussey H. Isolation from Candida albicans of a functional homolog of the Saccharomyces cerevisiae KRE1 gene, which is involved in cell wall beta-glucan synthesis. J Bacteriol. 1991 Nov;173(21):6859–6864. doi: 10.1128/jb.173.21.6859-6864.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Boone C., Sommer S. S., Hensel A., Bussey H. Yeast KRE genes provide evidence for a pathway of cell wall beta-glucan assembly. J Cell Biol. 1990 May;110(5):1833–1843. doi: 10.1083/jcb.110.5.1833. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Bowen A. R., Chen-Wu J. L., Momany M., Young R., Szaniszlo P. J., Robbins P. W. Classification of fungal chitin synthases. Proc Natl Acad Sci U S A. 1992 Jan 15;89(2):519–523. doi: 10.1073/pnas.89.2.519. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Bowser R., Müller H., Govindan B., Novick P. Sec8p and Sec15p are components of a plasma membrane-associated 19.5S particle that may function downstream of Sec4p to control exocytosis. J Cell Biol. 1992 Sep;118(5):1041–1056. doi: 10.1083/jcb.118.5.1041. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Brewster J. L., de Valoir T., Dwyer N. D., Winter E., Gustin M. C. An osmosensing signal transduction pathway in yeast. Science. 1993 Mar 19;259(5102):1760–1763. doi: 10.1126/science.7681220. [DOI] [PubMed] [Google Scholar]
  36. Briza P., Ellinger A., Winkler G., Breitenbach M. Characterization of a DL-dityrosine-containing macromolecule from yeast ascospore walls. J Biol Chem. 1990 Sep 5;265(25):15118–15123. [PubMed] [Google Scholar]
  37. Briza P., Ellinger A., Winkler G., Breitenbach M. Chemical composition of the yeast ascospore wall. The second outer layer consists of chitosan. J Biol Chem. 1988 Aug 15;263(23):11569–11574. [PubMed] [Google Scholar]
  38. Brockerhoff S. E., Davis T. N. Calmodulin concentrates at regions of cell growth in Saccharomyces cerevisiae. J Cell Biol. 1992 Aug;118(3):619–629. doi: 10.1083/jcb.118.3.619. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Brown J. L., Bussey H., Stewart R. C. Yeast Skn7p functions in a eukaryotic two-component regulatory pathway. EMBO J. 1994 Nov 1;13(21):5186–5194. doi: 10.1002/j.1460-2075.1994.tb06849.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Brown J. L., Bussey H. The yeast KRE9 gene encodes an O glycoprotein involved in cell surface beta-glucan assembly. Mol Cell Biol. 1993 Oct;13(10):6346–6356. doi: 10.1128/mcb.13.10.6346. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Brown J. L., Kossaczka Z., Jiang B., Bussey H. A mutational analysis of killer toxin resistance in Saccharomyces cerevisiae identifies new genes involved in cell wall (1-->6)-beta-glucan synthesis. Genetics. 1993 Apr;133(4):837–849. doi: 10.1093/genetics/133.4.837. [DOI] [PMC free article] [PubMed] [Google Scholar]
  42. Brown J. L., North S., Bussey H. SKN7, a yeast multicopy suppressor of a mutation affecting cell wall beta-glucan assembly, encodes a product with domains homologous to prokaryotic two-component regulators and to heat shock transcription factors. J Bacteriol. 1993 Nov;175(21):6908–6915. doi: 10.1128/jb.175.21.6908-6915.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Bulawa C. E. CSD2, CSD3, and CSD4, genes required for chitin synthesis in Saccharomyces cerevisiae: the CSD2 gene product is related to chitin synthases and to developmentally regulated proteins in Rhizobium species and Xenopus laevis. Mol Cell Biol. 1992 Apr;12(4):1764–1776. doi: 10.1128/mcb.12.4.1764. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Bulawa C. E. Genetics and molecular biology of chitin synthesis in fungi. Annu Rev Microbiol. 1993;47:505–534. doi: 10.1146/annurev.mi.47.100193.002445. [DOI] [PubMed] [Google Scholar]
  45. Bulawa C. E., Osmond B. C. Chitin synthase I and chitin synthase II are not required for chitin synthesis in vivo in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1990 Oct;87(19):7424–7428. doi: 10.1073/pnas.87.19.7424. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Bulawa C. E., Slater M., Cabib E., Au-Young J., Sburlati A., Adair W. L., Jr, Robbins P. W. The S. cerevisiae structural gene for chitin synthase is not required for chitin synthesis in vivo. Cell. 1986 Jul 18;46(2):213–225. doi: 10.1016/0092-8674(86)90738-5. [DOI] [PubMed] [Google Scholar]
  47. Butler A. R., O'Donnell R. W., Martin V. J., Gooday G. W., Stark M. J. Kluyveromyces lactis toxin has an essential chitinase activity. Eur J Biochem. 1991 Jul 15;199(2):483–488. doi: 10.1111/j.1432-1033.1991.tb16147.x. [DOI] [PubMed] [Google Scholar]
  48. Butler G., Thiele D. J. ACE2, an activator of yeast metallothionein expression which is homologous to SWI5. Mol Cell Biol. 1991 Jan;11(1):476–485. doi: 10.1128/mcb.11.1.476. [DOI] [PMC free article] [PubMed] [Google Scholar]
  49. Byers B., Goetsch L. A highly ordered ring of membrane-associated filaments in budding yeast. J Cell Biol. 1976 Jun;69(3):717–721. doi: 10.1083/jcb.69.3.717. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Bálint S., Farkaŝ V., Bauer S Biosynthesis of beta-glucans catalyzed by a particulate enzyme preparation from yeast. FEBS Lett. 1976 Apr 15;64(1):44–47. doi: 10.1016/0014-5793(76)80244-x. [DOI] [PubMed] [Google Scholar]
  51. Bénédetti H., Raths S., Crausaz F., Riezman H. The END3 gene encodes a protein that is required for the internalization step of endocytosis and for actin cytoskeleton organization in yeast. Mol Biol Cell. 1994 Sep;5(9):1023–1037. doi: 10.1091/mbc.5.9.1023. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Cabib E., Bowers B. Chitin and yeast budding. Localization of chitin in yeast bud scars. J Biol Chem. 1971 Jan 10;246(1):152–159. [PubMed] [Google Scholar]
  53. Cabib E., Bowers B., Sburlati A., Silverman S. J. Fungal cell wall synthesis: the construction of a biological structure. Microbiol Sci. 1988 Dec;5(12):370–375. [PubMed] [Google Scholar]
  54. Cabib E. Differential inhibition of chitin synthetases 1 and 2 from Saccharomyces cerevisiae by polyoxin D and nikkomycins. Antimicrob Agents Chemother. 1991 Jan;35(1):170–173. doi: 10.1128/aac.35.1.170. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. Cabib E., Duran A. Simple and sensitive procedure for screening yeast mutants that lyse at nonpermissive temperatures. J Bacteriol. 1975 Dec;124(3):1604–1606. doi: 10.1128/jb.124.3.1604-1606.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  56. Cabib E., Kang M. S. Fungal 1,3-beta-glucan synthase. Methods Enzymol. 1987;138:637–642. doi: 10.1016/0076-6879(87)38057-7. [DOI] [PubMed] [Google Scholar]
  57. Cabib E., Roberts R., Bowers B. Synthesis of the yeast cell wall and its regulation. Annu Rev Biochem. 1982;51:763–793. doi: 10.1146/annurev.bi.51.070182.003555. [DOI] [PubMed] [Google Scholar]
  58. Cabib E., Sburlati A., Bowers B., Silverman S. J. Chitin synthase 1, an auxiliary enzyme for chitin synthesis in Saccharomyces cerevisiae. J Cell Biol. 1989 May;108(5):1665–1672. doi: 10.1083/jcb.108.5.1665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Cabib E., Silverman S. J., Shaw J. A. Chitinase and chitin synthase 1: counterbalancing activities in cell separation of Saccharomyces cerevisiae. J Gen Microbiol. 1992 Jan;138(1):97–102. doi: 10.1099/00221287-138-1-97. [DOI] [PubMed] [Google Scholar]
  60. Cabib E. The synthesis and degradation of chitin. Adv Enzymol Relat Areas Mol Biol. 1987;59:59–101. doi: 10.1002/9780470123058.ch2. [DOI] [PubMed] [Google Scholar]
  61. Cabib E., Ulane R., Bowers B. A molecular model for morphogenesis: the primary septum of yeast. Curr Top Cell Regul. 1974;8(0):1–32. doi: 10.1016/b978-0-12-152808-9.50008-0. [DOI] [PubMed] [Google Scholar]
  62. Caras I. W., Weddell G. N., Williams S. R. Analysis of the signal for attachment of a glycophospholipid membrane anchor. J Cell Biol. 1989 Apr;108(4):1387–1396. doi: 10.1083/jcb.108.4.1387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  63. Chan C. S., Botstein D. Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast. Genetics. 1993 Nov;135(3):677–691. doi: 10.1093/genetics/135.3.677. [DOI] [PMC free article] [PubMed] [Google Scholar]
  64. Chant J. Cell polarity in yeast. Trends Genet. 1994 Sep;10(9):328–333. doi: 10.1016/0168-9525(94)90036-1. [DOI] [PubMed] [Google Scholar]
  65. Chant J., Corrado K., Pringle J. R., Herskowitz I. Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1. Cell. 1991 Jun 28;65(7):1213–1224. doi: 10.1016/0092-8674(91)90016-r. [DOI] [PubMed] [Google Scholar]
  66. Chant J., Herskowitz I. Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway. Cell. 1991 Jun 28;65(7):1203–1212. doi: 10.1016/0092-8674(91)90015-q. [DOI] [PubMed] [Google Scholar]
  67. Chant J., Mischke M., Mitchell E., Herskowitz I., Pringle J. R. Role of Bud3p in producing the axial budding pattern of yeast. J Cell Biol. 1995 May;129(3):767–778. doi: 10.1083/jcb.129.3.767. [DOI] [PMC free article] [PubMed] [Google Scholar]
  68. Chant J., Pringle J. R. Patterns of bud-site selection in the yeast Saccharomyces cerevisiae. J Cell Biol. 1995 May;129(3):751–765. doi: 10.1083/jcb.129.3.751. [DOI] [PMC free article] [PubMed] [Google Scholar]
  69. Chen-Wu J. L., Zwicker J., Bowen A. R., Robbins P. W. Expression of chitin synthase genes during yeast and hyphal growth phases of Candida albicans. Mol Microbiol. 1992 Feb;6(4):497–502. doi: 10.1111/j.1365-2958.1992.tb01494.x. [DOI] [PubMed] [Google Scholar]
  70. Chenevert J. Cell polarization directed by extracellular cues in yeast. Mol Biol Cell. 1994 Nov;5(11):1169–1175. doi: 10.1091/mbc.5.11.1169. [DOI] [PMC free article] [PubMed] [Google Scholar]
  71. Chenevert J., Corrado K., Bender A., Pringle J., Herskowitz I. A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains. Nature. 1992 Mar 5;356(6364):77–79. doi: 10.1038/356077a0. [DOI] [PubMed] [Google Scholar]
  72. Chenevert J., Valtz N., Herskowitz I. Identification of genes required for normal pheromone-induced cell polarization in Saccharomyces cerevisiae. Genetics. 1994 Apr;136(4):1287–1296. doi: 10.1093/genetics/136.4.1287. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Choi W. J., Cabib E. The use of divalent cations and pH for the determination of specific yeast chitin synthetases. Anal Biochem. 1994 Jun;219(2):368–372. doi: 10.1006/abio.1994.1278. [DOI] [PubMed] [Google Scholar]
  74. Choi W. J., Santos B., Durán A., Cabib E. Are yeast chitin synthases regulated at the transcriptional or the posttranslational level? Mol Cell Biol. 1994 Dec;14(12):7685–7694. doi: 10.1128/mcb.14.12.7685. [DOI] [PMC free article] [PubMed] [Google Scholar]
  75. Choi W. J., Sburlati A., Cabib E. Chitin synthase 3 from yeast has zymogenic properties that depend on both the CAL1 and the CAL3 genes. Proc Natl Acad Sci U S A. 1994 May 24;91(11):4727–4730. doi: 10.1073/pnas.91.11.4727. [DOI] [PMC free article] [PubMed] [Google Scholar]
  76. Chowdhury S., Smith K. W., Gustin M. C. Osmotic stress and the yeast cytoskeleton: phenotype-specific suppression of an actin mutation. J Cell Biol. 1992 Aug;118(3):561–571. doi: 10.1083/jcb.118.3.561. [DOI] [PMC free article] [PubMed] [Google Scholar]
  77. Cicchetti P., Mayer B. J., Thiel G., Baltimore D. Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho. Science. 1992 Aug 7;257(5071):803–806. doi: 10.1126/science.1379745. [DOI] [PubMed] [Google Scholar]
  78. Clancy M. J., Buten-Magee B., Straight D. J., Kennedy A. L., Partridge R. M., Magee P. T. Isolation of genes expressed preferentially during sporulation in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1983 May;80(10):3000–3004. doi: 10.1073/pnas.80.10.3000. [DOI] [PMC free article] [PubMed] [Google Scholar]
  79. Clark S. W., Meyer D. I. ACT3: a putative centractin homologue in S. cerevisiae is required for proper orientation of the mitotic spindle. J Cell Biol. 1994 Oct;127(1):129–138. doi: 10.1083/jcb.127.1.129. [DOI] [PMC free article] [PubMed] [Google Scholar]
  80. Cleves A. E., Novick P. J., Bankaitis V. A. Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function. J Cell Biol. 1989 Dec;109(6 Pt 1):2939–2950. doi: 10.1083/jcb.109.6.2939. [DOI] [PMC free article] [PubMed] [Google Scholar]
  81. Clotet J., Posas F., Hu G. Z., Ronne H., Ariño J. Role of protein phosphatase 2A in the control of glycogen metabolism in yeast. Eur J Biochem. 1995 Apr 1;229(1):207–214. [PubMed] [Google Scholar]
  82. Conzelmann A., Puoti A., Lester R. L., Desponds C. Two different types of lipid moieties are present in glycophosphoinositol-anchored membrane proteins of Saccharomyces cerevisiae. EMBO J. 1992 Feb;11(2):457–466. doi: 10.1002/j.1460-2075.1992.tb05075.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  83. Conzelmann A., Riezman H., Desponds C., Bron C. A major 125-kd membrane glycoprotein of Saccharomyces cerevisiae is attached to the lipid bilayer through an inositol-containing phospholipid. EMBO J. 1988 Jul;7(7):2233–2240. doi: 10.1002/j.1460-2075.1988.tb03063.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  84. Correa J. U., Elango N., Polacheck I., Cabib E. Endochitinase, a mannan-associated enzyme from Saccharomyces cerevisiae. J Biol Chem. 1982 Feb 10;257(3):1392–1397. [PubMed] [Google Scholar]
  85. Correa J., Vazquez de Aldana C. R., San Segundo P., del Rey F. Genetic mapping of 1,3-beta-glucanase-encoding genes in Saccharomyces cerevisiae. Curr Genet. 1992 Oct;22(4):283–288. doi: 10.1007/BF00317922. [DOI] [PubMed] [Google Scholar]
  86. Costigan C., Gehrung S., Snyder M. A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth. Mol Cell Biol. 1992 Mar;12(3):1162–1178. doi: 10.1128/mcb.12.3.1162. [DOI] [PMC free article] [PubMed] [Google Scholar]
  87. Costigan C., Kolodrubetz D., Snyder M. NHP6A and NHP6B, which encode HMG1-like proteins, are candidates for downstream components of the yeast SLT2 mitogen-activated protein kinase pathway. Mol Cell Biol. 1994 Apr;14(4):2391–2403. doi: 10.1128/mcb.14.4.2391. [DOI] [PMC free article] [PubMed] [Google Scholar]
  88. Costigan C., Snyder M. SLK1, a yeast homolog of MAP kinase activators, has a RAS/cAMP-independent role in nutrient sensing. Mol Gen Genet. 1994 May 10;243(3):286–296. doi: 10.1007/BF00301064. [DOI] [PubMed] [Google Scholar]
  89. Cvrcková F., Nasmyth K. Yeast G1 cyclins CLN1 and CLN2 and a GAP-like protein have a role in bud formation. EMBO J. 1993 Dec 15;12(13):5277–5286. doi: 10.1002/j.1460-2075.1993.tb06223.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  90. Da Cruz e Silva E. F., Hughes V., McDonald P., Stark M. J., Cohen P. T. Protein phosphatase 2Bw and protein phosphatase Z are Saccharomyces cerevisiae enzymes. Biochim Biophys Acta. 1991 Jun 13;1089(2):269–272. doi: 10.1016/0167-4781(91)90023-f. [DOI] [PubMed] [Google Scholar]
  91. De Nobel J. G., Klis F. M., Ram A., Van Unen H., Priem J., Munnik T., Van Den Ende H. Cyclic variations in the permeability of the cell wall of Saccharomyces cerevisiae. Yeast. 1991 Aug-Sep;7(6):589–598. doi: 10.1002/yea.320070606. [DOI] [PubMed] [Google Scholar]
  92. Debono M., Gordee R. S. Antibiotics that inhibit fungal cell wall development. Annu Rev Microbiol. 1994;48:471–497. doi: 10.1146/annurev.mi.48.100194.002351. [DOI] [PubMed] [Google Scholar]
  93. Di Como C. J., Chang H., Arndt K. T. Activation of CLN1 and CLN2 G1 cyclin gene expression by BCK2. Mol Cell Biol. 1995 Apr;15(4):1835–1846. doi: 10.1128/mcb.15.4.1835. [DOI] [PMC free article] [PubMed] [Google Scholar]
  94. DiDomenico B. J., Brown N. H., Lupisella J., Greene J. R., Yanko M., Koltin Y. Homologs of the yeast neck filament associated genes: isolation and sequence analysis of Candida albicans CDC3 and CDC10. Mol Gen Genet. 1994 Mar;242(6):689–698. doi: 10.1007/BF00283424. [DOI] [PubMed] [Google Scholar]
  95. Dohrmann P. R., Butler G., Tamai K., Dorland S., Greene J. R., Thiele D. J., Stillman D. J. Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase. Genes Dev. 1992 Jan;6(1):93–104. doi: 10.1101/gad.6.1.93. [DOI] [PubMed] [Google Scholar]
  96. Donnelly S. F., Pocklington M. J., Pallotta D., Orr E. A proline-rich protein, verprolin, involved in cytoskeletal organization and cellular growth in the yeast Saccharomyces cerevisiae. Mol Microbiol. 1993 Nov;10(3):585–596. doi: 10.1111/j.1365-2958.1993.tb00930.x. [DOI] [PubMed] [Google Scholar]
  97. Douglas C. M., Foor F., Marrinan J. A., Morin N., Nielsen J. B., Dahl A. M., Mazur P., Baginsky W., Li W., el-Sherbeini M. The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12907–12911. doi: 10.1073/pnas.91.26.12907. [DOI] [PMC free article] [PubMed] [Google Scholar]
  98. Douglas C. M., Marrinan J. A., Li W., Kurtz M. B. A Saccharomyces cerevisiae mutant with echinocandin-resistant 1,3-beta-D-glucan synthase. J Bacteriol. 1994 Sep;176(18):5686–5696. doi: 10.1128/jb.176.18.5686-5696.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  99. Drees B., Brown C., Barrell B. G., Bretscher A. Tropomyosin is essential in yeast, yet the TPM1 and TPM2 products perform distinct functions. J Cell Biol. 1995 Feb;128(3):383–392. doi: 10.1083/jcb.128.3.383. [DOI] [PMC free article] [PubMed] [Google Scholar]
  100. Drubin D. G., Jones H. D., Wertman K. F. Actin structure and function: roles in mitochondrial organization and morphogenesis in budding yeast and identification of the phalloidin-binding site. Mol Biol Cell. 1993 Dec;4(12):1277–1294. doi: 10.1091/mbc.4.12.1277. [DOI] [PMC free article] [PubMed] [Google Scholar]
  101. Drubin D. G., Miller K. G., Botstein D. Yeast actin-binding proteins: evidence for a role in morphogenesis. J Cell Biol. 1988 Dec;107(6 Pt 2):2551–2561. doi: 10.1083/jcb.107.6.2551. [DOI] [PMC free article] [PubMed] [Google Scholar]
  102. Drubin D. G., Mulholland J., Zhu Z. M., Botstein D. Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I. Nature. 1990 Jan 18;343(6255):288–290. doi: 10.1038/343288a0. [DOI] [PubMed] [Google Scholar]
  103. Dunn B., Stearns T., Botstein D. Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4. Nature. 1993 Apr 8;362(6420):563–565. doi: 10.1038/362563a0. [DOI] [PubMed] [Google Scholar]
  104. Dunn T. M., Shortle D. Null alleles of SAC7 suppress temperature-sensitive actin mutations in Saccharomyces cerevisiae. Mol Cell Biol. 1990 May;10(5):2308–2314. doi: 10.1128/mcb.10.5.2308. [DOI] [PMC free article] [PubMed] [Google Scholar]
  105. Duran A., Cabib E., Bowers B. Chitin synthetase distribution on the yeast plasma membrane. Science. 1979 Jan 26;203(4378):363–365. doi: 10.1126/science.366747. [DOI] [PubMed] [Google Scholar]
  106. Duran A., Cabib E. Solubilization and partial purification of yeast chitin synthetase. Confirmation of the zymogenic nature of the enzyme. J Biol Chem. 1978 Jun 25;253(12):4419–4425. [PubMed] [Google Scholar]
  107. Durrens P., Revardel E., Bonneu M., Aigle M. Evidence for a branched pathway in the polarized cell division of Saccharomyces cerevisiae. Curr Genet. 1995 Feb;27(3):213–216. doi: 10.1007/BF00326151. [DOI] [PubMed] [Google Scholar]
  108. Durán A., Bowers B., Cabib E. Chitin synthetase zymogen is attached to the yeast plasma membrane. Proc Natl Acad Sci U S A. 1975 Oct;72(10):3952–3955. doi: 10.1073/pnas.72.10.3952. [DOI] [PMC free article] [PubMed] [Google Scholar]
  109. Díaz M., Sanchez Y., Bennett T., Sun C. R., Godoy C., Tamanoi F., Duran A., Perez P. The Schizosaccharomyces pombe cwg2+ gene codes for the beta subunit of a geranylgeranyltransferase type I required for beta-glucan synthesis. EMBO J. 1993 Dec 15;12(13):5245–5254. doi: 10.1002/j.1460-2075.1993.tb06220.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  110. Díaz S., Zínker S., Ruiz-Herrera J. Alterations in the cell wall of Saccharomyces cerevisiae induced by the alpha sex factor or a mutation in the cell cycle. Antonie Van Leeuwenhoek. 1992 May;61(4):269–276. doi: 10.1007/BF00713935. [DOI] [PubMed] [Google Scholar]
  111. Elango N., Correa J. U., Cabib E. Secretory character of yeast chitinase. J Biol Chem. 1982 Feb 10;257(3):1398–1400. [PubMed] [Google Scholar]
  112. Enderlin C. S., Selitrennikoff C. P. Cloning and characterization of a Neurospora crassa gene required for (1,3) beta-glucan synthase activity and cell wall formation. Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9500–9504. doi: 10.1073/pnas.91.20.9500. [DOI] [PMC free article] [PubMed] [Google Scholar]
  113. Eng W. K., Faucette L., McLaughlin M. M., Cafferkey R., Koltin Y., Morris R. A., Young P. R., Johnson R. K., Livi G. P. The yeast FKS1 gene encodes a novel membrane protein, mutations in which confer FK506 and cyclosporin A hypersensitivity and calcineurin-dependent growth. Gene. 1994 Dec 30;151(1-2):61–71. doi: 10.1016/0378-1119(94)90633-5. [DOI] [PubMed] [Google Scholar]
  114. Epstein C. B., Cross F. R. CLB5: a novel B cyclin from budding yeast with a role in S phase. Genes Dev. 1992 Sep;6(9):1695–1706. doi: 10.1101/gad.6.9.1695. [DOI] [PubMed] [Google Scholar]
  115. Farkas I., Hardy T. A., DePaoli-Roach A. A., Roach P. J. Isolation of the GSY1 gene encoding yeast glycogen synthase and evidence for the existence of a second gene. J Biol Chem. 1990 Dec 5;265(34):20879–20886. [PubMed] [Google Scholar]
  116. Farkas V., Biely P., Bauer S. Extracellular beta-glucanases of the yeast, Saccharomyces cerevisiae. Biochim Biophys Acta. 1973 Sep 15;321(1):246–255. doi: 10.1016/0005-2744(73)90079-x. [DOI] [PubMed] [Google Scholar]
  117. Ferguson M. A. Colworth Medal Lecture. Glycosyl-phosphatidylinositol membrane anchors: the tale of a tail. Biochem Soc Trans. 1992 May;20(2):243–256. doi: 10.1042/bst0200243. [DOI] [PubMed] [Google Scholar]
  118. Fincher G. B., Lock P. A., Morgan M. M., Lingelbach K., Wettenhall R. E., Mercer J. F., Brandt A., Thomsen K. K. Primary structure of the (1-->3,1-->4)-beta-D-glucan 4-glucohydrolase from barley aleurone. Proc Natl Acad Sci U S A. 1986 Apr;83(7):2081–2085. doi: 10.1073/pnas.83.7.2081. [DOI] [PMC free article] [PubMed] [Google Scholar]
  119. Fishel B. R., Sperry A. O., Garrard W. T. Yeast calmodulin and a conserved nuclear protein participate in the in vivo binding of a matrix association region. Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5623–5627. doi: 10.1073/pnas.90.12.5623. [DOI] [PMC free article] [PubMed] [Google Scholar]
  120. Fleet G. H., Manners D. J. Isolation and composition of an alkali-soluble glucan from the cell walls of Saccharomyces cerevisiae. J Gen Microbiol. 1976 May;94(1):180–192. doi: 10.1099/00221287-94-1-180. [DOI] [PubMed] [Google Scholar]
  121. Fleet G. H., Phaff H. J. Glucanases in Schizosaccharomyces. Isolation and properties of the cell wall-associated beta(1 leads to 3)-glucanases. J Biol Chem. 1974 Mar 25;249(6):1717–1728. [PubMed] [Google Scholar]
  122. Flescher E. G., Madden K., Snyder M. Components required for cytokinesis are important for bud site selection in yeast. J Cell Biol. 1993 Jul;122(2):373–386. doi: 10.1083/jcb.122.2.373. [DOI] [PMC free article] [PubMed] [Google Scholar]
  123. Flick J. S., Johnston M. GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats. Mol Cell Biol. 1991 Oct;11(10):5101–5112. doi: 10.1128/mcb.11.10.5101. [DOI] [PMC free article] [PubMed] [Google Scholar]
  124. Flick J. S., Thorner J. Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae. Mol Cell Biol. 1993 Sep;13(9):5861–5876. doi: 10.1128/mcb.13.9.5861. [DOI] [PMC free article] [PubMed] [Google Scholar]
  125. Font de Mora J., Gil R., Sentandreu R., Herrero E. Isolation and characterization of Saccharomyces cerevisiae mutants resistant to aculeacin A. Antimicrob Agents Chemother. 1991 Dec;35(12):2596–2601. doi: 10.1128/aac.35.12.2596. [DOI] [PMC free article] [PubMed] [Google Scholar]
  126. Font de Mora J., Valentín E., Herrero E., Sentandreu R. Glycoprotein molecules in the walls of Schizosaccharomyces pombe wild-type cells and a morphologically altered mutant resistant to papulacandin B. J Gen Microbiol. 1990 Nov;136(11):2251–2259. doi: 10.1099/00221287-136-11-2251. [DOI] [PubMed] [Google Scholar]
  127. Ford S. K., Pringle J. R. Cellular morphogenesis in the Saccharomyces cerevisiae cell cycle: localization of the CDC11 gene product and the timing of events at the budding site. Dev Genet. 1991;12(4):281–292. doi: 10.1002/dvg.1020120405. [DOI] [PubMed] [Google Scholar]
  128. Frevert J., Ballou C. E. Saccharomyces cerevisiae structural cell wall mannoprotein. Biochemistry. 1985 Jan 29;24(3):753–759. doi: 10.1021/bi00324a033. [DOI] [PubMed] [Google Scholar]
  129. Friesen H., Lunz R., Doyle S., Segall J. Mutation of the SPS1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation. Genes Dev. 1994 Sep 15;8(18):2162–2175. doi: 10.1101/gad.8.18.2162. [DOI] [PubMed] [Google Scholar]
  130. Fujita A., Oka C., Arikawa Y., Katagai T., Tonouchi A., Kuhara S., Misumi Y. A yeast gene necessary for bud-site selection encodes a protein similar to insulin-degrading enzymes. Nature. 1994 Dec 8;372(6506):567–570. doi: 10.1038/372567a0. [DOI] [PubMed] [Google Scholar]
  131. Gabriel M., Kopecká M. Disruption of the actin cytoskeleton in budding yeast results in formation of an aberrant cell wall. Microbiology. 1995 Apr;141(Pt 4):891–899. doi: 10.1099/13500872-141-4-891. [DOI] [PubMed] [Google Scholar]
  132. Gallwitz D., Seidel R. Molecular cloning of the actin gene from yeast Saccharomyces cerevisiae. Nucleic Acids Res. 1980 Mar 11;8(5):1043–1059. doi: 10.1093/nar/8.5.1043. [DOI] [PMC free article] [PubMed] [Google Scholar]
  133. Gallwitz D., Sures I. Structure of a split yeast gene: complete nucleotide sequence of the actin gene in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1980 May;77(5):2546–2550. doi: 10.1073/pnas.77.5.2546. [DOI] [PMC free article] [PubMed] [Google Scholar]
  134. Garber A. T., Segall J. The SPS4 gene of Saccharomyces cerevisiae encodes a major sporulation-specific mRNA. Mol Cell Biol. 1986 Dec;6(12):4478–4485. doi: 10.1128/mcb.6.12.4478. [DOI] [PMC free article] [PubMed] [Google Scholar]
  135. Gaughran J. P., Lai M. H., Kirsch D. R., Silverman S. J. Nikkomycin Z is a specific inhibitor of Saccharomyces cerevisiae chitin synthase isozyme Chs3 in vitro and in vivo. J Bacteriol. 1994 Sep;176(18):5857–5860. doi: 10.1128/jb.176.18.5857-5860.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  136. Gehrung S., Snyder M. The SPA2 gene of Saccharomyces cerevisiae is important for pheromone-induced morphogenesis and efficient mating. J Cell Biol. 1990 Oct;111(4):1451–1464. doi: 10.1083/jcb.111.4.1451. [DOI] [PMC free article] [PubMed] [Google Scholar]
  137. Georgopapadakou N. H., Tkacz J. S. The fungal cell wall as a drug target. Trends Microbiol. 1995 Mar;3(3):98–104. doi: 10.1016/s0966-842x(00)88890-3. [DOI] [PubMed] [Google Scholar]
  138. Gerber L. D., Kodukula K., Udenfriend S. Phosphatidylinositol glycan (PI-G) anchored membrane proteins. Amino acid requirements adjacent to the site of cleavage and PI-G attachment in the COOH-terminal signal peptide. J Biol Chem. 1992 Jun 15;267(17):12168–12173. [PubMed] [Google Scholar]
  139. Ghiara J. B., Richardson H. E., Sugimoto K., Henze M., Lew D. J., Wittenberg C., Reed S. I. A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell. 1991 Apr 5;65(1):163–174. doi: 10.1016/0092-8674(91)90417-w. [DOI] [PubMed] [Google Scholar]
  140. Gimeno C. J., Ljungdahl P. O., Styles C. A., Fink G. R. Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: regulation by starvation and RAS. Cell. 1992 Mar 20;68(6):1077–1090. doi: 10.1016/0092-8674(92)90079-r. [DOI] [PubMed] [Google Scholar]
  141. Gold S. E., Kronstad J. W. Disruption of two genes for chitin synthase in the phytopathogenic fungus Ustilago maydis. Mol Microbiol. 1994 Mar;11(5):897–902. doi: 10.1111/j.1365-2958.1994.tb00368.x. [DOI] [PubMed] [Google Scholar]
  142. Goldschmidt-Clermont P. J., Mendelsohn M. E., Gibbs J. B. Rac and Rho in control. Curr Biol. 1992 Dec;2(12):669–671. doi: 10.1016/0960-9822(92)90135-w. [DOI] [PubMed] [Google Scholar]
  143. Gottlin-Ninfa E., Kaback D. B. Isolation and functional analysis of sporulation-induced transcribed sequences from Saccharomyces cerevisiae. Mol Cell Biol. 1986 Jun;6(6):2185–2197. doi: 10.1128/mcb.6.6.2185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  144. Govindan B., Bowser R., Novick P. The role of Myo2, a yeast class V myosin, in vesicular transport. J Cell Biol. 1995 Mar;128(6):1055–1068. doi: 10.1083/jcb.128.6.1055. [DOI] [PMC free article] [PubMed] [Google Scholar]
  145. Haarer B. K., Lillie S. H., Adams A. E., Magdolen V., Bandlow W., Brown S. S. Purification of profilin from Saccharomyces cerevisiae and analysis of profilin-deficient cells. J Cell Biol. 1990 Jan;110(1):105–114. doi: 10.1083/jcb.110.1.105. [DOI] [PMC free article] [PubMed] [Google Scholar]
  146. Haarer B. K., Petzold A. S., Brown S. S. Mutational analysis of yeast profilin. Mol Cell Biol. 1993 Dec;13(12):7864–7873. doi: 10.1128/mcb.13.12.7864. [DOI] [PMC free article] [PubMed] [Google Scholar]
  147. Haarer B. K., Petzold A., Lillie S. H., Brown S. S. Identification of MYO4, a second class V myosin gene in yeast. J Cell Sci. 1994 Apr;107(Pt 4):1055–1064. doi: 10.1242/jcs.107.4.1055. [DOI] [PubMed] [Google Scholar]
  148. Haarer B. K., Pringle J. R. Immunofluorescence localization of the Saccharomyces cerevisiae CDC12 gene product to the vicinity of the 10-nm filaments in the mother-bud neck. Mol Cell Biol. 1987 Oct;7(10):3678–3687. doi: 10.1128/mcb.7.10.3678. [DOI] [PMC free article] [PubMed] [Google Scholar]
  149. Hall A. Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu Rev Cell Biol. 1994;10:31–54. doi: 10.1146/annurev.cb.10.110194.000335. [DOI] [PubMed] [Google Scholar]
  150. Hamburger D., Egerton M., Riezman H. Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins. J Cell Biol. 1995 May;129(3):629–639. doi: 10.1083/jcb.129.3.629. [DOI] [PMC free article] [PubMed] [Google Scholar]
  151. Harata M., Karwan A., Wintersberger U. An essential gene of Saccharomyces cerevisiae coding for an actin-related protein. Proc Natl Acad Sci U S A. 1994 Aug 16;91(17):8258–8262. doi: 10.1073/pnas.91.17.8258. [DOI] [PMC free article] [PubMed] [Google Scholar]
  152. Hartland R. P., Emerson G. W., Sullivan P. A. A secreted beta-glucan-branching enzyme from Candida albicans. Proc Biol Sci. 1991 Nov 22;246(1316):155–160. doi: 10.1098/rspb.1991.0138. [DOI] [PubMed] [Google Scholar]
  153. Hartland R. P., Vermeulen C. A., Klis F. M., Sietsma J. H., Wessels J. G. The linkage of (1-3)-beta-glucan to chitin during cell wall assembly in Saccharomyces cerevisiae. Yeast. 1994 Dec;10(12):1591–1599. doi: 10.1002/yea.320101208. [DOI] [PubMed] [Google Scholar]
  154. Hartwell L. H., Culotti J., Pringle J. R., Reid B. J. Genetic control of the cell division cycle in yeast. Science. 1974 Jan 11;183(4120):46–51. doi: 10.1126/science.183.4120.46. [DOI] [PubMed] [Google Scholar]
  155. Hartwell L. H. Genetic control of the cell division cycle in yeast. IV. Genes controlling bud emergence and cytokinesis. Exp Cell Res. 1971 Dec;69(2):265–276. doi: 10.1016/0014-4827(71)90223-0. [DOI] [PubMed] [Google Scholar]
  156. He B., Chen P., Chen S. Y., Vancura K. L., Michaelis S., Powers S. RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11373–11377. doi: 10.1073/pnas.88.24.11373. [DOI] [PMC free article] [PubMed] [Google Scholar]
  157. Healy A. M., Zolnierowicz S., Stapleton A. E., Goebl M., DePaoli-Roach A. A., Pringle J. R. CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase. Mol Cell Biol. 1991 Nov;11(11):5767–5780. doi: 10.1128/mcb.11.11.5767. [DOI] [PMC free article] [PubMed] [Google Scholar]
  158. Herscovics A., Orlean P. Glycoprotein biosynthesis in yeast. FASEB J. 1993 Apr 1;7(6):540–550. doi: 10.1096/fasebj.7.6.8472892. [DOI] [PubMed] [Google Scholar]
  159. Herskowitz I. Life cycle of the budding yeast Saccharomyces cerevisiae. Microbiol Rev. 1988 Dec;52(4):536–553. doi: 10.1128/mr.52.4.536-553.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  160. Herskowitz I. MAP kinase pathways in yeast: for mating and more. Cell. 1995 Jan 27;80(2):187–197. doi: 10.1016/0092-8674(95)90402-6. [DOI] [PubMed] [Google Scholar]
  161. Hien N. H., Fleet G. H. Separation and characterization of six (1 leads to 3)-beta-glucanases from Saccharomyces cerevisiae. J Bacteriol. 1983 Dec;156(3):1204–1213. doi: 10.1128/jb.156.3.1204-1213.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  162. Hill K., Boone C., Goebl M., Puccia R., Sdicu A. M., Bussey H. Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins. Genetics. 1992 Feb;130(2):273–283. doi: 10.1093/genetics/130.2.273. [DOI] [PMC free article] [PubMed] [Google Scholar]
  163. Holaway B. L., Lehman D. J., Primerano D. A., Magee P. T., Clancy M. J. Sporulation-regulated genes of Saccharomyces cerevisiae. Curr Genet. 1985;10(3):163–169. doi: 10.1007/BF00798745. [DOI] [PubMed] [Google Scholar]
  164. Holtzman D. A., Yang S., Drubin D. G. Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae. J Cell Biol. 1993 Aug;122(3):635–644. doi: 10.1083/jcb.122.3.635. [DOI] [PMC free article] [PubMed] [Google Scholar]
  165. Hong Z., Mann P., Brown N. H., Tran L. E., Shaw K. J., Hare R. S., DiDomenico B. Cloning and characterization of KNR4, a yeast gene involved in (1,3)-beta-glucan synthesis. Mol Cell Biol. 1994 Feb;14(2):1017–1025. doi: 10.1128/mcb.14.2.1017. [DOI] [PMC free article] [PubMed] [Google Scholar]
  166. Hong Z., Mann P., Shaw K. J., Didomenico B. Analysis of beta-glucans and chitin in a Saccharomyces cerevisiae cell wall mutant using high-performance liquid chromatography. Yeast. 1994 Aug;10(8):1083–1092. doi: 10.1002/yea.320100810. [DOI] [PubMed] [Google Scholar]
  167. Hopper A. K., Magee P. T., Welch S. K., Friedman M., Hall B. D. Macromolecule synthesis and breakdown in relation to sporulation and meiosis in yeast. J Bacteriol. 1974 Aug;119(2):619–628. doi: 10.1128/jb.119.2.619-628.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  168. Horisberger M., Vonlanthen M. Location of mannan and chitin on thin sections of budding yeasts with gold markers. Arch Microbiol. 1977 Oct 24;115(1):1–7. doi: 10.1007/BF00427837. [DOI] [PubMed] [Google Scholar]
  169. Hu G. Z., Ronne H. Overexpression of yeast PAM1 gene permits survival without protein phosphatase 2A and induces a filamentous phenotype. J Biol Chem. 1994 Feb 4;269(5):3429–3435. [PubMed] [Google Scholar]
  170. Huffaker T. C., Robbins P. W. Yeast mutants deficient in protein glycosylation. Proc Natl Acad Sci U S A. 1983 Dec;80(24):7466–7470. doi: 10.1073/pnas.80.24.7466. [DOI] [PMC free article] [PubMed] [Google Scholar]
  171. Huffaker T. C., Thomas J. H., Botstein D. Diverse effects of beta-tubulin mutations on microtubule formation and function. J Cell Biol. 1988 Jun;106(6):1997–2010. doi: 10.1083/jcb.106.6.1997. [DOI] [PMC free article] [PubMed] [Google Scholar]
  172. Hughes V., Müller A., Stark M. J., Cohen P. T. Both isoforms of protein phosphatase Z are essential for the maintenance of cell size and integrity in Saccharomyces cerevisiae in response to osmotic stress. Eur J Biochem. 1993 Aug 15;216(1):269–279. doi: 10.1111/j.1432-1033.1993.tb18142.x. [DOI] [PubMed] [Google Scholar]
  173. Hutchins K., Bussey H. Cell wall receptor for yeast killer toxin: involvement of (1 leads to 6)-beta-D-glucan. J Bacteriol. 1983 Apr;154(1):161–169. doi: 10.1128/jb.154.1.161-169.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  174. Häusler A., Ballou L., Ballou C. E., Robbins P. W. Yeast glycoprotein biosynthesis: MNT1 encodes an alpha-1,2-mannosyltransferase involved in O-glycosylation. Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):6846–6850. doi: 10.1073/pnas.89.15.6846. [DOI] [PMC free article] [PubMed] [Google Scholar]
  175. Häusler A., Robbins P. W. Glycosylation in Saccharomyces cerevisiae: cloning and characterization of an alpha-1,2-mannosyltransferase structural gene. Glycobiology. 1992 Feb;2(1):77–84. doi: 10.1093/glycob/2.1.77. [DOI] [PubMed] [Google Scholar]
  176. Iida H., Nakamura H., Ono T., Okumura M. S., Anraku Y. MID1, a novel Saccharomyces cerevisiae gene encoding a plasma membrane protein, is required for Ca2+ influx and mating. Mol Cell Biol. 1994 Dec;14(12):8259–8271. doi: 10.1128/mcb.14.12.8259. [DOI] [PMC free article] [PubMed] [Google Scholar]
  177. Iida K., Moriyama K., Matsumoto S., Kawasaki H., Nishida E., Yahara I. Isolation of a yeast essential gene, COF1, that encodes a homologue of mammalian cofilin, a low-M(r) actin-binding and depolymerizing protein. Gene. 1993 Feb 14;124(1):115–120. doi: 10.1016/0378-1119(93)90770-4. [DOI] [PubMed] [Google Scholar]
  178. Irie K., Araki H., Oshima Y. A new protein kinase, SSP31, modulating the SMP3 gene-product involved in plasmid maintenance in Saccharomyces cerevisiae. Gene. 1991 Dec 1;108(1):139–144. doi: 10.1016/0378-1119(91)90499-2. [DOI] [PubMed] [Google Scholar]
  179. Irie K., Araki H., Oshima Y. Mutations in a Saccharomyces cerevisiae host showing increased holding stability of the heterologous plasmid pSR1. Mol Gen Genet. 1991 Feb;225(2):257–265. doi: 10.1007/BF00269857. [DOI] [PubMed] [Google Scholar]
  180. Irie K., Takase M., Lee K. S., Levin D. E., Araki H., Matsumoto K., Oshima Y. MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen-activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C. Mol Cell Biol. 1993 May;13(5):3076–3083. doi: 10.1128/mcb.13.5.3076. [DOI] [PMC free article] [PubMed] [Google Scholar]
  181. Jackson C. L., Konopka J. B., Hartwell L. H. S. cerevisiae alpha pheromone receptors activate a novel signal transduction pathway for mating partner discrimination. Cell. 1991 Oct 18;67(2):389–402. doi: 10.1016/0092-8674(91)90190-a. [DOI] [PubMed] [Google Scholar]
  182. Jacobs C. W., Adams A. E., Szaniszlo P. J., Pringle J. R. Functions of microtubules in the Saccharomyces cerevisiae cell cycle. J Cell Biol. 1988 Oct;107(4):1409–1426. doi: 10.1083/jcb.107.4.1409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  183. Jelinek-Kelly S., Akiyama T., Saunier B., Tkacz J. S., Herscovics A. Characterization of a specific alpha-mannosidase involved in oligosaccharide processing in Saccharomyces cerevisiae. J Biol Chem. 1985 Feb 25;260(4):2253–2257. [PubMed] [Google Scholar]
  184. Johnson B. F. Lysis of yeast cell walls induced by 2-deoxyglucose at their sites of glucan synthesis. J Bacteriol. 1968 Mar;95(3):1169–1172. doi: 10.1128/jb.95.3.1169-1172.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  185. Johnson D. I., Pringle J. R. Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity. J Cell Biol. 1990 Jul;111(1):143–152. doi: 10.1083/jcb.111.1.143. [DOI] [PMC free article] [PubMed] [Google Scholar]
  186. Johnston G. C., Prendergast J. A., Singer R. A. The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles. J Cell Biol. 1991 May;113(3):539–551. doi: 10.1083/jcb.113.3.539. [DOI] [PMC free article] [PubMed] [Google Scholar]
  187. Johnston L. H., Lowndes N. F. Cell cycle control of DNA synthesis in budding yeast. Nucleic Acids Res. 1992 May 25;20(10):2403–2410. doi: 10.1093/nar/20.10.2403. [DOI] [PMC free article] [PubMed] [Google Scholar]
  188. Kaback D. B., Feldberg L. R. Saccharomyces cerevisiae exhibits a sporulation-specific temporal pattern of transcript accumulation. Mol Cell Biol. 1985 Apr;5(4):751–761. doi: 10.1128/mcb.5.4.751. [DOI] [PMC free article] [PubMed] [Google Scholar]
  189. Kallal L. A., Bhattacharyya M., Grove S. N., Iannacone R. F., Pugh T. A., Primerano D. A., Clancy M. J. Functional analysis of the sporulation-specific SPR6 gene of Saccharomyces cerevisiae. Curr Genet. 1990 Nov;18(4):293–301. doi: 10.1007/BF00318210. [DOI] [PubMed] [Google Scholar]
  190. Kane S. M., Roth R. Carbohydrate metabolism during ascospore development in yeast. J Bacteriol. 1974 Apr;118(1):8–14. doi: 10.1128/jb.118.1.8-14.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  191. Kang M. S., Cabib E. Regulation of fungal cell wall growth: a guanine nucleotide-binding, proteinaceous component required for activity of (1----3)-beta-D-glucan synthase. Proc Natl Acad Sci U S A. 1986 Aug;83(16):5808–5812. doi: 10.1073/pnas.83.16.5808. [DOI] [PMC free article] [PubMed] [Google Scholar]
  192. Kao G., Mannix D. G., Holaway B. L., Finn M. C., Bonny A. E., Clancy M. J. Dependence of inessential late gene expression on early meiotic events in Saccharomyces cerevisiae. Mol Gen Genet. 1989 Feb;215(3):490–500. doi: 10.1007/BF00427048. [DOI] [PubMed] [Google Scholar]
  193. Karpova T. S., Lepetit M. M., Cooper J. A. Mutations that enhance the cap2 null mutant phenotype in Saccharomyces cerevisiae affect the actin cytoskeleton, morphogenesis and pattern of growth. Genetics. 1993 Nov;135(3):693–709. doi: 10.1093/genetics/135.3.693. [DOI] [PMC free article] [PubMed] [Google Scholar]
  194. Kasahara S., Yamada H., Mio T., Shiratori Y., Miyamoto C., Yabe T., Nakajima T., Ichishima E., Furuichi Y. Cloning of the Saccharomyces cerevisiae gene whose overexpression overcomes the effects of HM-1 killer toxin, which inhibits beta-glucan synthesis. J Bacteriol. 1994 Mar;176(5):1488–1499. doi: 10.1128/jb.176.5.1488-1499.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  195. Kaya T., Aikawa M., Matsumoto T. Purification and properties of alpha-mannosidase from bakers' yeast. J Biochem. 1977 Nov;82(5):1443–1449. doi: 10.1093/oxfordjournals.jbchem.a131832. [DOI] [PubMed] [Google Scholar]
  196. Kilmartin J. V., Adams A. E. Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J Cell Biol. 1984 Mar;98(3):922–933. doi: 10.1083/jcb.98.3.922. [DOI] [PMC free article] [PubMed] [Google Scholar]
  197. Kim H. B., Haarer B. K., Pringle J. R. Cellular morphogenesis in the Saccharomyces cerevisiae cell cycle: localization of the CDC3 gene product and the timing of events at the budding site. J Cell Biol. 1991 Feb;112(4):535–544. doi: 10.1083/jcb.112.4.535. [DOI] [PMC free article] [PubMed] [Google Scholar]
  198. Kim Y. J., Francisco L., Chen G. C., Marcotte E., Chan C. S. Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation. J Cell Biol. 1994 Dec;127(5):1381–1394. doi: 10.1083/jcb.127.5.1381. [DOI] [PMC free article] [PubMed] [Google Scholar]
  199. Klebl F., Tanner W. Molecular cloning of a cell wall exo-beta-1,3-glucanase from Saccharomyces cerevisiae. J Bacteriol. 1989 Nov;171(11):6259–6264. doi: 10.1128/jb.171.11.6259-6264.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  200. Klis F. M. Review: cell wall assembly in yeast. Yeast. 1994 Jul;10(7):851–869. doi: 10.1002/yea.320100702. [DOI] [PubMed] [Google Scholar]
  201. Koch A. L. How bacteria grow and divide in spite of internal hydrostatic pressure. Can J Microbiol. 1985 Dec;31(12):1071–1084. doi: 10.1139/m85-204. [DOI] [PubMed] [Google Scholar]
  202. Koch C. A., Anderson D., Moran M. F., Ellis C., Pawson T. SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science. 1991 May 3;252(5006):668–674. doi: 10.1126/science.1708916. [DOI] [PubMed] [Google Scholar]
  203. Kollár R., Petráková E., Ashwell G., Robbins P. W., Cabib E. Architecture of the yeast cell wall. The linkage between chitin and beta(1-->3)-glucan. J Biol Chem. 1995 Jan 20;270(3):1170–1178. doi: 10.1074/jbc.270.3.1170. [DOI] [PubMed] [Google Scholar]
  204. Konopka J. B. AFR1 acts in conjunction with the alpha-factor receptor to promote morphogenesis and adaptation. Mol Cell Biol. 1993 Nov;13(11):6876–6888. doi: 10.1128/mcb.13.11.6876. [DOI] [PMC free article] [PubMed] [Google Scholar]
  205. Konopka J. B., DeMattei C., Davis C. AFR1 promotes polarized apical morphogenesis in Saccharomyces cerevisiae. Mol Cell Biol. 1995 Feb;15(2):723–730. doi: 10.1128/mcb.15.2.723. [DOI] [PMC free article] [PubMed] [Google Scholar]
  206. Konopka J. B., Fields S. The pheromone signal pathway in Saccharomyces cerevisiae. Antonie Van Leeuwenhoek. 1992 Aug;62(1-2):95–108. doi: 10.1007/BF00584465. [DOI] [PubMed] [Google Scholar]
  207. Kopecká M., Gabriel M. Actin cortical cytoskeleton and cell wall synthesis in regenerating protoplasts of the Saccharomyces cerevisiae actin mutant DBY 1693. Microbiology. 1995 Jun;141(Pt 6):1289–1299. doi: 10.1099/13500872-141-6-1289. [DOI] [PubMed] [Google Scholar]
  208. Kopecká M., Kreger D. R. Assembly of microfibrils in vivo and in vitro from (1----3)-beta-D-glucan synthesized by protoplasts of Saccharomyces cerevisiae. Arch Microbiol. 1986 Jan;143(4):387–395. doi: 10.1007/BF00412807. [DOI] [PubMed] [Google Scholar]
  209. Kopecká M., Phaff H. J., Fleet G. H. Demonstration of a fibrillar component in the cell wall of the yeast Saccharomyces cerevisiae and its chemical nature. J Cell Biol. 1974 Jul;62(1):66–76. doi: 10.1083/jcb.62.1.66. [DOI] [PMC free article] [PubMed] [Google Scholar]
  210. Krisak L., Strich R., Winters R. S., Hall J. P., Mallory M. J., Kreitzer D., Tuan R. S., Winter E. SMK1, a developmentally regulated MAP kinase, is required for spore wall assembly in Saccharomyces cerevisiae. Genes Dev. 1994 Sep 15;8(18):2151–2161. doi: 10.1101/gad.8.18.2151. [DOI] [PubMed] [Google Scholar]
  211. Kron S. J., Styles C. A., Fink G. R. Symmetric cell division in pseudohyphae of the yeast Saccharomyces cerevisiae. Mol Biol Cell. 1994 Sep;5(9):1003–1022. doi: 10.1091/mbc.5.9.1003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  212. Krátký Z., Biely P., Bauer S. Wall mannan of Saccharomyces cerevisiae. Metabolic stability and release into growth medium. Biochim Biophys Acta. 1975 Sep 8;404(1):1–6. doi: 10.1016/0304-4165(75)90141-5. [DOI] [PubMed] [Google Scholar]
  213. Kukuruzinska M. A., Bergh M. L., Jackson B. J. Protein glycosylation in yeast. Annu Rev Biochem. 1987;56:915–944. doi: 10.1146/annurev.bi.56.070187.004411. [DOI] [PubMed] [Google Scholar]
  214. Kuranda M. J., Robbins P. W. Chitinase is required for cell separation during growth of Saccharomyces cerevisiae. J Biol Chem. 1991 Oct 15;266(29):19758–19767. [PubMed] [Google Scholar]
  215. Kuranda M. J., Robbins P. W. Cloning and heterologous expression of glycosidase genes from Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1987 May;84(9):2585–2589. doi: 10.1073/pnas.84.9.2585. [DOI] [PMC free article] [PubMed] [Google Scholar]
  216. Kübler E., Riezman H. Actin and fimbrin are required for the internalization step of endocytosis in yeast. EMBO J. 1993 Jul;12(7):2855–2862. doi: 10.1002/j.1460-2075.1993.tb05947.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  217. Kühne C., Linder P. A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle. EMBO J. 1993 Sep;12(9):3437–3447. doi: 10.1002/j.1460-2075.1993.tb06018.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  218. Law D. T., Segall J. The SPS100 gene of Saccharomyces cerevisiae is activated late in the sporulation process and contributes to spore wall maturation. Mol Cell Biol. 1988 Feb;8(2):912–922. doi: 10.1128/mcb.8.2.912. [DOI] [PMC free article] [PubMed] [Google Scholar]
  219. Leal-Morales C. A., Bracker C. E., Bartnicki-Garcia S. Localization of chitin synthetase in cell-free homogenates of Saccharomyces cerevisiae: chitosomes and plasma membrane. Proc Natl Acad Sci U S A. 1988 Nov;85(22):8516–8520. doi: 10.1073/pnas.85.22.8516. [DOI] [PMC free article] [PubMed] [Google Scholar]
  220. Lee K. S., Hines L. K., Levin D. E. A pair of functionally redundant yeast genes (PPZ1 and PPZ2) encoding type 1-related protein phosphatases function within the PKC1-mediated pathway. Mol Cell Biol. 1993 Sep;13(9):5843–5853. doi: 10.1128/mcb.13.9.5843. [DOI] [PMC free article] [PubMed] [Google Scholar]
  221. Lee K. S., Irie K., Gotoh Y., Watanabe Y., Araki H., Nishida E., Matsumoto K., Levin D. E. A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C. Mol Cell Biol. 1993 May;13(5):3067–3075. doi: 10.1128/mcb.13.5.3067. [DOI] [PMC free article] [PubMed] [Google Scholar]
  222. Lee K. S., Levin D. E. Dominant mutations in a gene encoding a putative protein kinase (BCK1) bypass the requirement for a Saccharomyces cerevisiae protein kinase C homolog. Mol Cell Biol. 1992 Jan;12(1):172–182. doi: 10.1128/mcb.12.1.172. [DOI] [PMC free article] [PubMed] [Google Scholar]
  223. Lees J. F., Shneidman P. S., Skuntz S. F., Carden M. J., Lazzarini R. A. The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it. EMBO J. 1988 Jul;7(7):1947–1955. doi: 10.1002/j.1460-2075.1988.tb03032.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  224. Levin D. E., Bartlett-Heubusch E. Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect. J Cell Biol. 1992 Mar;116(5):1221–1229. doi: 10.1083/jcb.116.5.1221. [DOI] [PMC free article] [PubMed] [Google Scholar]
  225. Levin D. E., Bowers B., Chen C. Y., Kamada Y., Watanabe M. Dissecting the protein kinase C/MAP kinase signalling pathway of Saccharomyces cerevisiae. Cell Mol Biol Res. 1994;40(3):229–239. [PubMed] [Google Scholar]
  226. Levin D. E., Fields F. O., Kunisawa R., Bishop J. M., Thorner J. A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle. Cell. 1990 Jul 27;62(2):213–224. doi: 10.1016/0092-8674(90)90360-q. [DOI] [PubMed] [Google Scholar]
  227. Lew D. J., Reed S. I. A cell cycle checkpoint monitors cell morphogenesis in budding yeast. J Cell Biol. 1995 May;129(3):739–749. doi: 10.1083/jcb.129.3.739. [DOI] [PMC free article] [PubMed] [Google Scholar]
  228. Lew D. J., Reed S. I. Cell cycle control of morphogenesis in budding yeast. Curr Opin Genet Dev. 1995 Feb;5(1):17–23. doi: 10.1016/s0959-437x(95)90048-9. [DOI] [PubMed] [Google Scholar]
  229. Lew D. J., Reed S. I. Morphogenesis in the yeast cell cycle: regulation by Cdc28 and cyclins. J Cell Biol. 1993 Mar;120(6):1305–1320. doi: 10.1083/jcb.120.6.1305. [DOI] [PMC free article] [PubMed] [Google Scholar]
  230. Li R., Zheng Y., Drubin D. G. Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast. J Cell Biol. 1995 Feb;128(4):599–615. doi: 10.1083/jcb.128.4.599. [DOI] [PMC free article] [PubMed] [Google Scholar]
  231. Lillie S. H., Brown S. S. Immunofluorescence localization of the unconventional myosin, Myo2p, and the putative kinesin-related protein, Smy1p, to the same regions of polarized growth in Saccharomyces cerevisiae. J Cell Biol. 1994 May;125(4):825–842. doi: 10.1083/jcb.125.4.825. [DOI] [PMC free article] [PubMed] [Google Scholar]
  232. Lillie S. H., Brown S. S. Suppression of a myosin defect by a kinesin-related gene. Nature. 1992 Mar 26;356(6367):358–361. doi: 10.1038/356358a0. [DOI] [PubMed] [Google Scholar]
  233. Lin F. C., Arndt K. T. The role of Saccharomyces cerevisiae type 2A phosphatase in the actin cytoskeleton and in entry into mitosis. EMBO J. 1995 Jun 15;14(12):2745–2759. doi: 10.1002/j.1460-2075.1995.tb07275.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  234. Lipke P. N., Ballou C. E. Altered immunochemical reactivity of Saccharomyces cerevisiae a-cells after alpha-factor-induced morphogenesis. J Bacteriol. 1980 Mar;141(3):1170–1177. doi: 10.1128/jb.141.3.1170-1177.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  235. Lipke P. N., Kurjan J. Sexual agglutination in budding yeasts: structure, function, and regulation of adhesion glycoproteins. Microbiol Rev. 1992 Mar;56(1):180–194. doi: 10.1128/mr.56.1.180-194.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  236. Lipke P. N., Taylor A., Ballou C. E. Morphogenic effects of alpha-factor on Saccharomyces cerevisiae a cells. J Bacteriol. 1976 Jul;127(1):610–618. doi: 10.1128/jb.127.1.610-618.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  237. Lipke P. N., Wojciechowicz D., Kurjan J. AG alpha 1 is the structural gene for the Saccharomyces cerevisiae alpha-agglutinin, a cell surface glycoprotein involved in cell-cell interactions during mating. Mol Cell Biol. 1989 Aug;9(8):3155–3165. doi: 10.1128/mcb.9.8.3155. [DOI] [PMC free article] [PubMed] [Google Scholar]
  238. Liu H. P., Bretscher A. Disruption of the single tropomyosin gene in yeast results in the disappearance of actin cables from the cytoskeleton. Cell. 1989 Apr 21;57(2):233–242. doi: 10.1016/0092-8674(89)90961-6. [DOI] [PubMed] [Google Scholar]
  239. Liu H., Bretscher A. Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transport. J Cell Biol. 1992 Jul;118(2):285–299. doi: 10.1083/jcb.118.2.285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  240. Liu H., Styles C. A., Fink G. R. Elements of the yeast pheromone response pathway required for filamentous growth of diploids. Science. 1993 Dec 10;262(5140):1741–1744. doi: 10.1126/science.8259520. [DOI] [PubMed] [Google Scholar]
  241. Lu C. F., Kurjan J., Lipke P. N. A pathway for cell wall anchorage of Saccharomyces cerevisiae alpha-agglutinin. Mol Cell Biol. 1994 Jul;14(7):4825–4833. doi: 10.1128/mcb.14.7.4825. [DOI] [PMC free article] [PubMed] [Google Scholar]
  242. Lussier M., Gentzsch M., Sdicu A. M., Bussey H., Tanner W. Protein O-glycosylation in yeast. The PMT2 gene specifies a second protein O-mannosyltransferase that functions in addition to the PMT1-encoded activity. J Biol Chem. 1995 Feb 10;270(6):2770–2775. doi: 10.1074/jbc.270.6.2770. [DOI] [PubMed] [Google Scholar]
  243. López-Romero E., Ruiz-Herrera J. Biosynthesis of beta-glucans by cell-free extracts from Saccharomyces cerevisiae. Biochim Biophys Acta. 1977 Dec 22;500(2):372–384. doi: 10.1016/0304-4165(77)90028-9. [DOI] [PubMed] [Google Scholar]
  244. Machesky L. M., Poland T. D. Profilin as a potential mediator of membrane-cytoskeleton communication. Trends Cell Biol. 1993 Nov;3(11):381–385. doi: 10.1016/0962-8924(93)90087-h. [DOI] [PubMed] [Google Scholar]
  245. Madaule P., Axel R., Myers A. M. Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1987 Feb;84(3):779–783. doi: 10.1073/pnas.84.3.779. [DOI] [PMC free article] [PubMed] [Google Scholar]
  246. Madden K., Costigan C., Snyder M. Cell polarity and morphogenesis in Saccharomyces cerevisiae. Trends Cell Biol. 1992 Jan;2(1):22–29. doi: 10.1016/0962-8924(92)90140-i. [DOI] [PubMed] [Google Scholar]
  247. Madden K., Snyder M. Specification of sites for polarized growth in Saccharomyces cerevisiae and the influence of external factors on site selection. Mol Biol Cell. 1992 Sep;3(9):1025–1035. doi: 10.1091/mbc.3.9.1025. [DOI] [PMC free article] [PubMed] [Google Scholar]
  248. Maeda T., Tsai A. Y., Saito H. Mutations in a protein tyrosine phosphatase gene (PTP2) and a protein serine/threonine phosphatase gene (PTC1) cause a synthetic growth defect in Saccharomyces cerevisiae. Mol Cell Biol. 1993 Sep;13(9):5408–5417. doi: 10.1128/mcb.13.9.5408. [DOI] [PMC free article] [PubMed] [Google Scholar]
  249. Maeda T., Wurgler-Murphy S. M., Saito H. A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature. 1994 May 19;369(6477):242–245. doi: 10.1038/369242a0. [DOI] [PubMed] [Google Scholar]
  250. Magdolen V., Drubin D. G., Mages G., Bandlow W. High levels of profilin suppress the lethality caused by overproduction of actin in yeast cells. FEBS Lett. 1993 Jan 18;316(1):41–47. doi: 10.1016/0014-5793(93)81733-g. [DOI] [PubMed] [Google Scholar]
  251. Magdolen V., Oechsner U., Müller G., Bandlow W. The intron-containing gene for yeast profilin (PFY) encodes a vital function. Mol Cell Biol. 1988 Dec;8(12):5108–5115. doi: 10.1128/mcb.8.12.5108. [DOI] [PMC free article] [PubMed] [Google Scholar]
  252. Mager W. H., Varela J. C. Osmostress response of the yeast Saccharomyces. Mol Microbiol. 1993 Oct;10(2):253–258. [PubMed] [Google Scholar]
  253. Mahrenholz A. M., Wang Y. H., Roach P. J. Catalytic site of rabbit glycogen synthase isozymes. Identification of an active site lysine close to the amino terminus of the subunit. J Biol Chem. 1988 Aug 5;263(22):10561–10567. [PubMed] [Google Scholar]
  254. Maia J. C. Hexosamine and cell wall biogenesis in the aquatic fungus Blastocladiella emersonii. FASEB J. 1994 Aug;8(11):848–853. doi: 10.1096/fasebj.8.11.8070634. [DOI] [PubMed] [Google Scholar]
  255. Manners D. J., Masson A. J., Patterson J. C., Björndal H., Lindberg B. The structure of a beta-(1--6)-D-glucan from yeast cell walls. Biochem J. 1973 Sep;135(1):31–36. doi: 10.1042/bj1350031. [DOI] [PMC free article] [PubMed] [Google Scholar]
  256. Manners D. J., Masson A. J., Patterson J. C. The structure of a beta-(1 leads to 3)-D-glucan from yeast cell walls. Biochem J. 1973 Sep;135(1):19–30. doi: 10.1042/bj1350019. [DOI] [PMC free article] [PubMed] [Google Scholar]
  257. Manser E., Leung T., Salihuddin H., Zhao Z. S., Lim L. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature. 1994 Jan 6;367(6458):40–46. doi: 10.1038/367040a0. [DOI] [PubMed] [Google Scholar]
  258. Martín H., Arroyo J., Sánchez M., Molina M., Nombela C. Activity of the yeast MAP kinase homologue Slt2 is critically required for cell integrity at 37 degrees C. Mol Gen Genet. 1993 Oct;241(1-2):177–184. doi: 10.1007/BF00280215. [DOI] [PubMed] [Google Scholar]
  259. Matsui Y., Toh-E A. Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEM1. Mol Cell Biol. 1992 Dec;12(12):5690–5699. doi: 10.1128/mcb.12.12.5690. [DOI] [PMC free article] [PubMed] [Google Scholar]
  260. Matsui Y., Toh-e A. Isolation and characterization of two novel ras superfamily genes in Saccharomyces cerevisiae. Gene. 1992 May 1;114(1):43–49. doi: 10.1016/0378-1119(92)90705-t. [DOI] [PubMed] [Google Scholar]
  261. Mayer M. L., Caplin B. E., Marshall M. S. CDC43 and RAM2 encode the polypeptide subunits of a yeast type I protein geranylgeranyltransferase. J Biol Chem. 1992 Oct 15;267(29):20589–20593. [PubMed] [Google Scholar]
  262. Mazzoni C., Zarov P., Rambourg A., Mann C. The SLT2 (MPK1) MAP kinase homolog is involved in polarized cell growth in Saccharomyces cerevisiae. J Cell Biol. 1993 Dec;123(6 Pt 2):1821–1833. doi: 10.1083/jcb.123.6.1821. [DOI] [PMC free article] [PubMed] [Google Scholar]
  263. McLellan W. L., Jr, McDaniel L. E., Lampen J. O. Purification of phosphomannanase and its action on the yeast cell wall. J Bacteriol. 1970 Apr;102(1):261–270. doi: 10.1128/jb.102.1.261-270.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  264. Meaden P., Hill K., Wagner J., Slipetz D., Sommer S. S., Bussey H. The yeast KRE5 gene encodes a probable endoplasmic reticulum protein required for (1----6)-beta-D-glucan synthesis and normal cell growth. Mol Cell Biol. 1990 Jun;10(6):3013–3019. doi: 10.1128/mcb.10.6.3013. [DOI] [PMC free article] [PubMed] [Google Scholar]
  265. Miller P. J., Johnson D. I. Cdc42p GTPase is involved in controlling polarized cell growth in Schizosaccharomyces pombe. Mol Cell Biol. 1994 Feb;14(2):1075–1083. doi: 10.1128/mcb.14.2.1075. [DOI] [PMC free article] [PubMed] [Google Scholar]
  266. Miyamoto S., Ohya Y., Ohsumi Y., Anraku Y. Nucleotide sequence of the CLS4 (CDC24) gene of Saccharomyces cerevisiae. Gene. 1987;54(1):125–132. doi: 10.1016/0378-1119(87)90354-4. [DOI] [PubMed] [Google Scholar]
  267. Miyamoto S., Ohya Y., Sano Y., Sakaguchi S., Iida H., Anraku Y. A DBL-homologous region of the yeast CLS4/CDC24 gene product is important for Ca(2+)-modulated bud assembly. Biochem Biophys Res Commun. 1991 Dec 16;181(2):604–610. doi: 10.1016/0006-291x(91)91233-3. [DOI] [PubMed] [Google Scholar]
  268. Mol P. C., Park H. M., Mullins J. T., Cabib E. A GTP-binding protein regulates the activity of (1-->3)-beta-glucan synthase, an enzyme directly involved in yeast cell wall morphogenesis. J Biol Chem. 1994 Dec 9;269(49):31267–31274. [PubMed] [Google Scholar]
  269. Molano J., Bowers B., Cabib E. Distribution of chitin in the yeast cell wall. An ultrastructural and chemical study. J Cell Biol. 1980 May;85(2):199–212. doi: 10.1083/jcb.85.2.199. [DOI] [PMC free article] [PubMed] [Google Scholar]
  270. Montijn R. C., van Rinsum J., van Schagen F. A., Klis F. M. Glucomannoproteins in the cell wall of Saccharomyces cerevisiae contain a novel type of carbohydrate side chain. J Biol Chem. 1994 Jul 29;269(30):19338–19342. [PubMed] [Google Scholar]
  271. Moon A. L., Janmey P. A., Louie K. A., Drubin D. G. Cofilin is an essential component of the yeast cortical cytoskeleton. J Cell Biol. 1993 Jan;120(2):421–435. doi: 10.1083/jcb.120.2.421. [DOI] [PMC free article] [PubMed] [Google Scholar]
  272. Mrsa V., Klebl F., Tanner W. Purification and characterization of the Saccharomyces cerevisiae BGL2 gene product, a cell wall endo-beta-1,3-glucanase. J Bacteriol. 1993 Apr;175(7):2102–2106. doi: 10.1128/jb.175.7.2102-2106.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  273. Muhua L., Karpova T. S., Cooper J. A. A yeast actin-related protein homologous to that in vertebrate dynactin complex is important for spindle orientation and nuclear migration. Cell. 1994 Aug 26;78(4):669–679. doi: 10.1016/0092-8674(94)90531-2. [DOI] [PubMed] [Google Scholar]
  274. Mulholland J., Preuss D., Moon A., Wong A., Drubin D., Botstein D. Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol. 1994 Apr;125(2):381–391. doi: 10.1083/jcb.125.2.381. [DOI] [PMC free article] [PubMed] [Google Scholar]
  275. Musacchio A., Gibson T., Rice P., Thompson J., Saraste M. The PH domain: a common piece in the structural patchwork of signalling proteins. Trends Biochem Sci. 1993 Sep;18(9):343–348. doi: 10.1016/0968-0004(93)90071-t. [DOI] [PubMed] [Google Scholar]
  276. Muthukumar G., Suhng S. H., Magee P. T., Jewell R. D., Primerano D. A. The Saccharomyces cerevisiae SPR1 gene encodes a sporulation-specific exo-1,3-beta-glucanase which contributes to ascospore thermoresistance. J Bacteriol. 1993 Jan;175(2):386–394. doi: 10.1128/jb.175.2.386-394.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  277. Na S., Hincapie M., McCusker J. H., Haber J. E. MOP2 (SLA2) affects the abundance of the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae. J Biol Chem. 1995 Mar 24;270(12):6815–6823. doi: 10.1074/jbc.270.12.6815. [DOI] [PubMed] [Google Scholar]
  278. Nagahashi S., Sudoh M., Ono N., Sawada R., Yamaguchi E., Uchida Y., Mio T., Takagi M., Arisawa M., Yamada-Okabe H. Characterization of chitin synthase 2 of Saccharomyces cerevisiae. Implication of two highly conserved domains as possible catalytic sites. J Biol Chem. 1995 Jun 9;270(23):13961–13967. doi: 10.1074/jbc.270.23.13961. [DOI] [PubMed] [Google Scholar]
  279. Nakatsuru S., Sudo K., Nakamura Y. Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae. Biochem Biophys Res Commun. 1994 Jul 15;202(1):82–87. doi: 10.1006/bbrc.1994.1896. [DOI] [PubMed] [Google Scholar]
  280. Nasmyth K. Control of the yeast cell cycle by the Cdc28 protein kinase. Curr Opin Cell Biol. 1993 Apr;5(2):166–179. doi: 10.1016/0955-0674(93)90099-c. [DOI] [PubMed] [Google Scholar]
  281. Navarro-García F., Sánchez M., Pla J., Nombela C. Functional characterization of the MKC1 gene of Candida albicans, which encodes a mitogen-activated protein kinase homolog related to cell integrity. Mol Cell Biol. 1995 Apr;15(4):2197–2206. doi: 10.1128/mcb.15.4.2197. [DOI] [PMC free article] [PubMed] [Google Scholar]
  282. Nebreda A. R., Vazquez C. R., Villa T. G., Villanueva J. R., del Rey F. Heterogeneous glycosylation of the EXG1 gene product accounts for the two extracellular exo-beta-glucanases of Saccharomyces cerevisiae. FEBS Lett. 1987 Aug 10;220(1):27–30. doi: 10.1016/0014-5793(87)80869-4. [DOI] [PubMed] [Google Scholar]
  283. Nebreda A. R., Villa T. G., Villanueva J. R., del Rey F. Cloning of genes related to exo-beta-glucanase production in Saccharomyces cerevisiae: characterization of an exo-beta-glucanase structural gene. Gene. 1986;47(2-3):245–259. doi: 10.1016/0378-1119(86)90068-5. [DOI] [PubMed] [Google Scholar]
  284. Neufeld T. P., Rubin G. M. The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins. Cell. 1994 May 6;77(3):371–379. doi: 10.1016/0092-8674(94)90152-x. [DOI] [PubMed] [Google Scholar]
  285. Newton D. L., Oldewurtel M. D., Krinks M. H., Shiloach J., Klee C. B. Agonist and antagonist properties of calmodulin fragments. J Biol Chem. 1984 Apr 10;259(7):4419–4426. [PubMed] [Google Scholar]
  286. Ng R., Abelson J. Isolation and sequence of the gene for actin in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1980 Jul;77(7):3912–3916. doi: 10.1073/pnas.77.7.3912. [DOI] [PMC free article] [PubMed] [Google Scholar]
  287. Nombela C., Molina M., Cenamor R., Sanchez M. Yeast beta-glucanases: a complex system of secreted enzymes. Microbiol Sci. 1988 Nov;5(11):328–332. [PubMed] [Google Scholar]
  288. Notario V., Kawai H., Cabib E. Interaction between yeast beta-(1 goes to 3)glucan synthetase and activating phosphorylated compounds. A kinetic study. J Biol Chem. 1982 Feb 25;257(4):1902–1905. [PubMed] [Google Scholar]
  289. Novick P., Botstein D. Phenotypic analysis of temperature-sensitive yeast actin mutants. Cell. 1985 Feb;40(2):405–416. doi: 10.1016/0092-8674(85)90154-0. [DOI] [PubMed] [Google Scholar]
  290. Novick P., Brennwald P. Friends and family: the role of the Rab GTPases in vesicular traffic. Cell. 1993 Nov 19;75(4):597–601. doi: 10.1016/0092-8674(93)90478-9. [DOI] [PubMed] [Google Scholar]
  291. Novick P., Field C., Schekman R. Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell. 1980 Aug;21(1):205–215. doi: 10.1016/0092-8674(80)90128-2. [DOI] [PubMed] [Google Scholar]
  292. Novick P., Osmond B. C., Botstein D. Suppressors of yeast actin mutations. Genetics. 1989 Apr;121(4):659–674. doi: 10.1093/genetics/121.4.659. [DOI] [PMC free article] [PubMed] [Google Scholar]
  293. Novick P., Schekman R. Export of major cell surface proteins is blocked in yeast secretory mutants. J Cell Biol. 1983 Feb;96(2):541–547. doi: 10.1083/jcb.96.2.541. [DOI] [PMC free article] [PubMed] [Google Scholar]
  294. Nuoffer C., Horvath A., Riezman H. Analysis of the sequence requirements for glycosylphosphatidylinositol anchoring of Saccharomyces cerevisiae Gas1 protein. J Biol Chem. 1993 May 15;268(14):10558–10563. [PubMed] [Google Scholar]
  295. Nuoffer C., Jenö P., Conzelmann A., Riezman H. Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane. Mol Cell Biol. 1991 Jan;11(1):27–37. doi: 10.1128/mcb.11.1.27. [DOI] [PMC free article] [PubMed] [Google Scholar]
  296. Ogita K., Miyamoto S., Koide H., Iwai T., Oka M., Ando K., Kishimoto A., Ikeda K., Fukami Y., Nishizuka Y. Protein kinase C in Saccharomyces cerevisiae: comparison with the mammalian enzyme. Proc Natl Acad Sci U S A. 1990 Jul;87(13):5011–5015. doi: 10.1073/pnas.87.13.5011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  297. Ohya Y., Botstein D. Diverse essential functions revealed by complementing yeast calmodulin mutants. Science. 1994 Feb 18;263(5149):963–966. doi: 10.1126/science.8310294. [DOI] [PubMed] [Google Scholar]
  298. Ohya Y., Goebl M., Goodman L. E., Petersen-Bjørn S., Friesen J. D., Tamanoi F., Anraku Y. Yeast CAL1 is a structural and functional homologue to the DPR1 (RAM) gene involved in ras processing. J Biol Chem. 1991 Jul 5;266(19):12356–12360. [PubMed] [Google Scholar]
  299. Ohya Y., Ohsumi Y., Anraku Y. Genetic study of the role of calcium ions in the cell division cycle of Saccharomyces cerevisiae: a calcium-dependent mutant and its trifluoperazine-dependent pseudorevertants. Mol Gen Genet. 1984;193(3):389–394. doi: 10.1007/BF00382073. [DOI] [PubMed] [Google Scholar]
  300. Ohya Y., Qadota H., Anraku Y., Pringle J. R., Botstein D. Suppression of yeast geranylgeranyl transferase I defect by alternative prenylation of two target GTPases, Rho1p and Cdc42p. Mol Biol Cell. 1993 Oct;4(10):1017–1025. doi: 10.1091/mbc.4.10.1017. [DOI] [PMC free article] [PubMed] [Google Scholar]
  301. Olivero I., Hernandez L. M., Larriba G. Regulation of beta-exoglucanase activity production by Saccharomyces cerevisiae in batch and continuous culture. Arch Microbiol. 1985 Nov;143(2):143–146. doi: 10.1007/BF00411037. [DOI] [PubMed] [Google Scholar]
  302. Opheim D. J. alpha-D-Mannosidase of Saccharomyces cerevisiae. Characterization and modulation of activity. Biochim Biophys Acta. 1978 May 11;524(1):121–130. doi: 10.1016/0005-2744(78)90110-9. [DOI] [PubMed] [Google Scholar]
  303. Orlean P., Ammer H., Watzele M., Tanner W. Synthesis of an O-glycosylated cell surface protein induced in yeast by alpha factor. Proc Natl Acad Sci U S A. 1986 Sep;83(17):6263–6266. doi: 10.1073/pnas.83.17.6263. [DOI] [PMC free article] [PubMed] [Google Scholar]
  304. Orlean P., Kuranda M. J., Albright C. F. Analysis of glycoproteins from Saccharomyces cerevisiae. Methods Enzymol. 1991;194:682–697. doi: 10.1016/0076-6879(91)94050-m. [DOI] [PubMed] [Google Scholar]
  305. Orlean P. Two chitin synthases in Saccharomyces cerevisiae. J Biol Chem. 1987 Apr 25;262(12):5732–5739. [PubMed] [Google Scholar]
  306. Pammer M., Briza P., Ellinger A., Schuster T., Stucka R., Feldmann H., Breitenbach M. DIT101 (CSD2, CAL1), a cell cycle-regulated yeast gene required for synthesis of chitin in cell walls and chitosan in spore walls. Yeast. 1992 Dec;8(12):1089–1099. doi: 10.1002/yea.320081211. [DOI] [PubMed] [Google Scholar]
  307. Paravicini G., Cooper M., Friedli L., Smith D. J., Carpentier J. L., Klig L. S., Payton M. A. The osmotic integrity of the yeast cell requires a functional PKC1 gene product. Mol Cell Biol. 1992 Nov;12(11):4896–4905. doi: 10.1128/mcb.12.11.4896. [DOI] [PMC free article] [PubMed] [Google Scholar]
  308. Park H. O., Chant J., Herskowitz I. BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast. Nature. 1993 Sep 16;365(6443):269–274. doi: 10.1038/365269a0. [DOI] [PubMed] [Google Scholar]
  309. Pastor F. I., Herrero E., Sentandreu R. Metabolism of Saccharomyces cerevisiae envelope mannoproteins. Arch Microbiol. 1982 Aug;132(2):144–148. doi: 10.1007/BF00508720. [DOI] [PubMed] [Google Scholar]
  310. Pawson T., Schlessingert J. SH2 and SH3 domains. Curr Biol. 1993 Jul 1;3(7):434–442. doi: 10.1016/0960-9822(93)90350-w. [DOI] [PubMed] [Google Scholar]
  311. Percival-Smith A., Segall J. Characterization and mutational analysis of a cluster of three genes expressed preferentially during sporulation of Saccharomyces cerevisiae. Mol Cell Biol. 1986 Jul;6(7):2443–2451. doi: 10.1128/mcb.6.7.2443. [DOI] [PMC free article] [PubMed] [Google Scholar]
  312. Percival-Smith A., Segall J. Isolation of DNA sequences preferentially expressed during sporulation in Saccharomyces cerevisiae. Mol Cell Biol. 1984 Jan;4(1):142–150. doi: 10.1128/mcb.4.1.142. [DOI] [PMC free article] [PubMed] [Google Scholar]
  313. Peterson J., Zheng Y., Bender L., Myers A., Cerione R., Bender A. Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast. J Cell Biol. 1994 Dec;127(5):1395–1406. doi: 10.1083/jcb.127.5.1395. [DOI] [PMC free article] [PubMed] [Google Scholar]
  314. Popolo L., Vai M., Gatti E., Porello S., Bonfante P., Balestrini R., Alberghina L. Physiological analysis of mutants indicates involvement of the Saccharomyces cerevisiae GPI-anchored protein gp115 in morphogenesis and cell separation. J Bacteriol. 1993 Apr;175(7):1879–1885. doi: 10.1128/jb.175.7.1879-1885.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  315. Posas F., Casamayor A., Ariño J. The PPZ protein phosphatases are involved in the maintenance of osmotic stability of yeast cells. FEBS Lett. 1993 Mar 8;318(3):282–286. doi: 10.1016/0014-5793(93)80529-4. [DOI] [PubMed] [Google Scholar]
  316. Pringle J. R. Staining of bud scars and other cell wall chitin with calcofluor. Methods Enzymol. 1991;194:732–735. doi: 10.1016/0076-6879(91)94055-h. [DOI] [PubMed] [Google Scholar]
  317. Qadota H., Ishii I., Fujiyama A., Ohya Y., Anraku Y. RHO gene products, putative small GTP-binding proteins, are important for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae. Yeast. 1992 Sep;8(9):735–741. doi: 10.1002/yea.320080906. [DOI] [PubMed] [Google Scholar]
  318. Ram A. F., Brekelmans S. S., Oehlen L. J., Klis F. M. Identification of two cell cycle regulated genes affecting the beta 1,3-glucan content of cell walls in Saccharomyces cerevisiae. FEBS Lett. 1995 Jan 23;358(2):165–170. doi: 10.1016/0014-5793(94)01418-z. [DOI] [PubMed] [Google Scholar]
  319. Ram A. F., Wolters A., Ten Hoopen R., Klis F. M. A new approach for isolating cell wall mutants in Saccharomyces cerevisiae by screening for hypersensitivity to calcofluor white. Yeast. 1994 Aug;10(8):1019–1030. doi: 10.1002/yea.320100804. [DOI] [PubMed] [Google Scholar]
  320. Ramírez M., Hernández L. M., Larriba G. A similar protein portion for two exoglucanases secreted by Saccharomyces cerevisiae. Arch Microbiol. 1989;151(5):391–398. doi: 10.1007/BF00416596. [DOI] [PubMed] [Google Scholar]
  321. Reed S. I., Hadwiger J. A., Lörincz A. T. Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28. Proc Natl Acad Sci U S A. 1985 Jun;82(12):4055–4059. doi: 10.1073/pnas.82.12.4055. [DOI] [PMC free article] [PubMed] [Google Scholar]
  322. Reed S. I. The selection of S. cerevisiae mutants defective in the start event of cell division. Genetics. 1980 Jul;95(3):561–577. doi: 10.1093/genetics/95.3.561. [DOI] [PMC free article] [PubMed] [Google Scholar]
  323. Reichelt B. Y., Fleet G. H. Isolation, properties, function, and regulation of endo-(1 leads to 3)-beta-glucanases in Schizosaccharomyces pombe. J Bacteriol. 1981 Sep;147(3):1085–1094. doi: 10.1128/jb.147.3.1085-1094.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  324. Reinhard J., Scheel A. A., Diekmann D., Hall A., Ruppert C., Bähler M. A novel type of myosin implicated in signalling by rho family GTPases. EMBO J. 1995 Feb 15;14(4):697–704. doi: 10.1002/j.1460-2075.1995.tb07048.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  325. Ribas J. C., Diaz M., Duran A., Perez P. Isolation and characterization of Schizosaccharomyces pombe mutants defective in cell wall (1-3)beta-D-glucan. J Bacteriol. 1991 Jun;173(11):3456–3462. doi: 10.1128/jb.173.11.3456-3462.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
  326. Ribas J. C., Roncero C., Rico H., Durán A. Characterization of a Schizosaccharomyces pombe morphological mutant altered in the galactomannan content. FEMS Microbiol Lett. 1991 Apr 15;63(2-3):263–267. doi: 10.1016/0378-1097(91)90096-s. [DOI] [PubMed] [Google Scholar]
  327. Ridruejo J. C., Muñoz M. D., Andaluz E., Larriba G. Inhibition of yeast exoglucanases by glucosidase inhibitors. Biochim Biophys Acta. 1989 Dec 8;993(2-3):179–185. doi: 10.1016/0304-4165(89)90161-x. [DOI] [PubMed] [Google Scholar]
  328. Roberts R. L., Bowers B., Slater M. L., Cabib E. Chitin synthesis and localization in cell division cycle mutants of Saccharomyces cerevisiae. Mol Cell Biol. 1983 May;3(5):922–930. doi: 10.1128/mcb.3.5.922. [DOI] [PMC free article] [PubMed] [Google Scholar]
  329. Roberts R. L., Fink G. R. Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth. Genes Dev. 1994 Dec 15;8(24):2974–2985. doi: 10.1101/gad.8.24.2974. [DOI] [PubMed] [Google Scholar]
  330. Robinson L. C., Menold M. M., Garrett S., Culbertson M. R. Casein kinase I-like protein kinases encoded by YCK1 and YCK2 are required for yeast morphogenesis. Mol Cell Biol. 1993 May;13(5):2870–2881. doi: 10.1128/mcb.13.5.2870. [DOI] [PMC free article] [PubMed] [Google Scholar]
  331. Robinson M. K., van Zyl W. H., Phizicky E. M., Broach J. R. TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation. Mol Cell Biol. 1994 Jun;14(6):3634–3645. doi: 10.1128/mcb.14.6.3634. [DOI] [PMC free article] [PubMed] [Google Scholar]
  332. Rodriguez J. R., Paterson B. M. Yeast myosin heavy chain mutant: maintenance of the cell type specific budding pattern and the normal deposition of chitin and cell wall components requires an intact myosin heavy chain gene. Cell Motil Cytoskeleton. 1990;17(4):301–308. doi: 10.1002/cm.970170405. [DOI] [PubMed] [Google Scholar]
  333. Roemer T., Bussey H. Yeast beta-glucan synthesis: KRE6 encodes a predicted type II membrane protein required for glucan synthesis in vivo and for glucan synthase activity in vitro. Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11295–11299. doi: 10.1073/pnas.88.24.11295. [DOI] [PMC free article] [PubMed] [Google Scholar]
  334. Roemer T., Delaney S., Bussey H. SKN1 and KRE6 define a pair of functional homologs encoding putative membrane proteins involved in beta-glucan synthesis. Mol Cell Biol. 1993 Jul;13(7):4039–4048. doi: 10.1128/mcb.13.7.4039. [DOI] [PMC free article] [PubMed] [Google Scholar]
  335. Roemer T., Paravicini G., Payton M. A., Bussey H. Characterization of the yeast (1-->6)-beta-glucan biosynthetic components, Kre6p and Skn1p, and genetic interactions between the PKC1 pathway and extracellular matrix assembly. J Cell Biol. 1994 Oct;127(2):567–579. doi: 10.1083/jcb.127.2.567. [DOI] [PMC free article] [PubMed] [Google Scholar]
  336. Roncero C., Durán A. Effect of Calcofluor white and Congo red on fungal cell wall morphogenesis: in vivo activation of chitin polymerization. J Bacteriol. 1985 Sep;163(3):1180–1185. doi: 10.1128/jb.163.3.1180-1185.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  337. Roncero C., Valdivieso M. H., Ribas J. C., Durán A. Effect of calcofluor white on chitin synthases from Saccharomyces cerevisiae. J Bacteriol. 1988 Apr;170(4):1945–1949. doi: 10.1128/jb.170.4.1945-1949.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  338. Roncero C., Valdivieso M. H., Ribas J. C., Durán A. Isolation and characterization of Saccharomyces cerevisiae mutants resistant to Calcofluor white. J Bacteriol. 1988 Apr;170(4):1950–1954. doi: 10.1128/jb.170.4.1950-1954.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  339. Ronne H., Carlberg M., Hu G. Z., Nehlin J. O. Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis. Mol Cell Biol. 1991 Oct;11(10):4876–4884. doi: 10.1128/mcb.11.10.4876. [DOI] [PMC free article] [PubMed] [Google Scholar]
  340. Roy A., Lu C. F., Marykwas D. L., Lipke P. N., Kurjan J. The AGA1 product is involved in cell surface attachment of the Saccharomyces cerevisiae cell adhesion glycoprotein a-agglutinin. Mol Cell Biol. 1991 Aug;11(8):4196–4206. doi: 10.1128/mcb.11.8.4196. [DOI] [PMC free article] [PubMed] [Google Scholar]
  341. San Segundo P., Correa J., Vazquez de Aldana C. R., del Rey F. SSG1, a gene encoding a sporulation-specific 1,3-beta-glucanase in Saccharomyces cerevisiae. J Bacteriol. 1993 Jun;175(12):3823–3837. doi: 10.1128/jb.175.12.3823-3837.1993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  342. Sanders S. L., Field C. M. Cell division. Septins in common? Curr Biol. 1994 Oct 1;4(10):907–910. doi: 10.1016/s0960-9822(00)00201-3. [DOI] [PubMed] [Google Scholar]
  343. Santos T., del Rey F., Conde J., Villanueva J. R., Nombela C. Saccharomyces cerevisiae mutant defective in exo-1,3-beta-glucanase production. J Bacteriol. 1979 Aug;139(2):333–338. doi: 10.1128/jb.139.2.333-338.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  344. Saporito-Irwin S. M., Birse C. E., Sypherd P. S., Fonzi W. A. PHR1, a pH-regulated gene of Candida albicans, is required for morphogenesis. Mol Cell Biol. 1995 Feb;15(2):601–613. doi: 10.1128/mcb.15.2.601. [DOI] [PMC free article] [PubMed] [Google Scholar]
  345. Saxena I. M., Brown R. M., Jr, Fevre M., Geremia R. A., Henrissat B. Multidomain architecture of beta-glycosyl transferases: implications for mechanism of action. J Bacteriol. 1995 Mar;177(6):1419–1424. doi: 10.1128/jb.177.6.1419-1424.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  346. Sburlati A., Cabib E. Chitin synthetase 2, a presumptive participant in septum formation in Saccharomyces cerevisiae. J Biol Chem. 1986 Nov 15;261(32):15147–15152. [PubMed] [Google Scholar]
  347. Schade B., Richter W., Spangenberg P., Venkov P. Evidence that the osmotically fragile yeast S. cerevisiae VY1160 is an actin mutant. Acta Histochem Suppl. 1991;41:193–200. [PubMed] [Google Scholar]
  348. Schekman R., Brawley V. Localized deposition of chitin on the yeast cell surface in response to mating pheromone. Proc Natl Acad Sci U S A. 1979 Feb;76(2):645–649. doi: 10.1073/pnas.76.2.645. [DOI] [PMC free article] [PubMed] [Google Scholar]
  349. Schekman R. Protein localization and membrane traffic in yeast. Annu Rev Cell Biol. 1985;1:115–143. doi: 10.1146/annurev.cb.01.110185.000555. [DOI] [PubMed] [Google Scholar]
  350. Schwob E., Martin R. P. New yeast actin-like gene required late in the cell cycle. Nature. 1992 Jan 9;355(6356):179–182. doi: 10.1038/355179a0. [DOI] [PubMed] [Google Scholar]
  351. Schwob E., Nasmyth K. CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae. Genes Dev. 1993 Jul;7(7A):1160–1175. doi: 10.1101/gad.7.7a.1160. [DOI] [PubMed] [Google Scholar]
  352. Sentandreu R., Elorza M. V., Villanueva J. R. Synthesis of yeast wall glucan. J Gen Microbiol. 1975 Sep;90(1):13–20. doi: 10.1099/00221287-90-1-13. [DOI] [PubMed] [Google Scholar]
  353. Shaw J. A., Mol P. C., Bowers B., Silverman S. J., Valdivieso M. H., Durán A., Cabib E. The function of chitin synthases 2 and 3 in the Saccharomyces cerevisiae cell cycle. J Cell Biol. 1991 Jul;114(1):111–123. doi: 10.1083/jcb.114.1.111. [DOI] [PMC free article] [PubMed] [Google Scholar]
  354. Shematek E. M., Braatz J. A., Cabib E. Biosynthesis of the yeast cell wall. I. Preparation and properties of beta-(1 leads to 3)glucan synthetase. J Biol Chem. 1980 Feb 10;255(3):888–894. [PubMed] [Google Scholar]
  355. Shematek E. M., Cabib E. Biosynthesis of the yeast cell wall. II. Regulation of beta-(1 leads to 3)glucan synthetase by ATP and GTP. J Biol Chem. 1980 Feb 10;255(3):895–902. [PubMed] [Google Scholar]
  356. Shibata N., Mizugami K., Takano K., Suzuki S. Isolation of mannan-protein complexes from viable cells of Saccharomyces cerevisiae X2180-1A wild type and Saccharomyces cerevisiae X2180-1 A-5 mutant strains by the action of Zymolyase-60,000. J Bacteriol. 1983 Nov;156(2):552–558. doi: 10.1128/jb.156.2.552-558.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  357. Shimizu J., Yoda K., Yamasaki M. The hypo-osmolarity-sensitive phenotype of the Saccharomyces cerevisiae hpo2 mutant is due to a mutation in PKC1, which regulates expression of beta-glucanase. Mol Gen Genet. 1994 Mar;242(6):641–648. doi: 10.1007/BF00283417. [DOI] [PubMed] [Google Scholar]
  358. Shinshi H., Wenzler H., Neuhaus J. M., Felix G., Hofsteenge J., Meins F. Evidence for N- and C-terminal processing of a plant defense-related enzyme: Primary structure of tobacco prepro-beta-1,3-glucanase. Proc Natl Acad Sci U S A. 1988 Aug;85(15):5541–5545. doi: 10.1073/pnas.85.15.5541. [DOI] [PMC free article] [PubMed] [Google Scholar]
  359. Sietsma J. H., Wessels J. G. The occurrence of glucosaminoglycan in the wall of Schizosaccharomyces pombe. J Gen Microbiol. 1990 Nov;136(11):2261–2265. doi: 10.1099/00221287-136-11-2261. [DOI] [PubMed] [Google Scholar]
  360. Silverman S. J., Sburlati A., Slater M. L., Cabib E. Chitin synthase 2 is essential for septum formation and cell division in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1988 Jul;85(13):4735–4739. doi: 10.1073/pnas.85.13.4735. [DOI] [PMC free article] [PubMed] [Google Scholar]
  361. Silverman S. J., Shaw J. A., Cabib E. Proteinase B is, indeed, not required for chitin synthetase 1 function in Saccharomyces cerevisiae. Biochem Biophys Res Commun. 1991 Jan 15;174(1):204–210. doi: 10.1016/0006-291x(91)90506-3. [DOI] [PubMed] [Google Scholar]
  362. Slater M. L., Bowers B., Cabib E. Formation of septum-like structures at locations remote from the budding sites in cytokinesis-defective mutants of Saccharomyces cerevisiae. J Bacteriol. 1985 May;162(2):763–767. doi: 10.1128/jb.162.2.763-767.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  363. Sloat B. F., Adams A., Pringle J. R. Roles of the CDC24 gene product in cellular morphogenesis during the Saccharomyces cerevisiae cell cycle. J Cell Biol. 1981 Jun;89(3):395–405. doi: 10.1083/jcb.89.3.395. [DOI] [PMC free article] [PubMed] [Google Scholar]
  364. Snyder M., Gehrung S., Page B. D. Studies concerning the temporal and genetic control of cell polarity in Saccharomyces cerevisiae. J Cell Biol. 1991 Aug;114(3):515–532. doi: 10.1083/jcb.114.3.515. [DOI] [PMC free article] [PubMed] [Google Scholar]
  365. Snyder M. The SPA2 protein of yeast localizes to sites of cell growth. J Cell Biol. 1989 Apr;108(4):1419–1429. doi: 10.1083/jcb.108.4.1419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  366. Stillman D. J., Bankier A. T., Seddon A., Groenhout E. G., Nasmyth K. A. Characterization of a transcription factor involved in mother cell specific transcription of the yeast HO gene. EMBO J. 1988 Feb;7(2):485–494. doi: 10.1002/j.1460-2075.1988.tb02836.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  367. Stossel T. P. On the crawling of animal cells. Science. 1993 May 21;260(5111):1086–1094. doi: 10.1126/science.8493552. [DOI] [PubMed] [Google Scholar]
  368. Strahl-Bolsinger S., Immervoll T., Deutzmann R., Tanner W. PMT1, the gene for a key enzyme of protein O-glycosylation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1993 Sep 1;90(17):8164–8168. doi: 10.1073/pnas.90.17.8164. [DOI] [PMC free article] [PubMed] [Google Scholar]
  369. Sudoh M., Nagahashi S., Doi M., Ohta A., Takagi M., Arisawa M. Cloning of the chitin synthase 3 gene from Candida albicans and its expression during yeast-hyphal transition. Mol Gen Genet. 1993 Nov;241(3-4):351–358. doi: 10.1007/BF00284688. [DOI] [PubMed] [Google Scholar]
  370. Surana U., Robitsch H., Price C., Schuster T., Fitch I., Futcher A. B., Nasmyth K. The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae. Cell. 1991 Apr 5;65(1):145–161. doi: 10.1016/0092-8674(91)90416-v. [DOI] [PubMed] [Google Scholar]
  371. Sutton A., Immanuel D., Arndt K. T. The SIT4 protein phosphatase functions in late G1 for progression into S phase. Mol Cell Biol. 1991 Apr;11(4):2133–2148. doi: 10.1128/mcb.11.4.2133. [DOI] [PMC free article] [PubMed] [Google Scholar]
  372. Sweeney F. P., Watts F. Z., Pocklington M. J., Orr E. The MYO1 gene from Saccharomyces cerevisiae: its complete nucleotide sequence. Nucleic Acids Res. 1990 Dec 11;18(23):7147–7147. doi: 10.1093/nar/18.23.7147. [DOI] [PMC free article] [PubMed] [Google Scholar]
  373. Szaniszlo P. J., Kang M. S., Cabib E. Stimulation of beta(1----3)glucan synthetase of various fungi by nucleoside triphosphates: generalized regulatory mechanism for cell wall biosynthesis. J Bacteriol. 1985 Mar;161(3):1188–1194. doi: 10.1128/jb.161.3.1188-1194.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  374. Sánchez A., Villanueva J. R., Villa T. G. Saccharomyces cerevisiae secretes 2 exo-beta-glucanases. FEBS Lett. 1982 Feb 22;138(2):209–212. doi: 10.1016/0014-5793(82)80443-2. [DOI] [PubMed] [Google Scholar]
  375. Takita M. A., Castilho-Valavicius B. Absence of cell wall chitin in Saccharomyces cerevisiae leads to resistance to Kluyveromyces lactis killer toxin. Yeast. 1993 Jun;9(6):589–598. doi: 10.1002/yea.320090605. [DOI] [PubMed] [Google Scholar]
  376. Tanner W., Lehle L. Protein glycosylation in yeast. Biochim Biophys Acta. 1987 Apr 27;906(1):81–99. doi: 10.1016/0304-4157(87)90006-2. [DOI] [PubMed] [Google Scholar]
  377. Toda T., Shimanuki M., Yanagida M. Two novel protein kinase C-related genes of fission yeast are essential for cell viability and implicated in cell shape control. EMBO J. 1993 May;12(5):1987–1995. doi: 10.1002/j.1460-2075.1993.tb05848.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  378. Torres L., Martín H., García-Saez M. I., Arroyo J., Molina M., Sánchez M., Nombela C. A protein kinase gene complements the lytic phenotype of Saccharomyces cerevisiae lyt2 mutants. Mol Microbiol. 1991 Nov;5(11):2845–2854. doi: 10.1111/j.1365-2958.1991.tb01993.x. [DOI] [PubMed] [Google Scholar]
  379. Trueheart J., Boeke J. D., Fink G. R. Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol Cell Biol. 1987 Jul;7(7):2316–2328. doi: 10.1128/mcb.7.7.2316. [DOI] [PMC free article] [PubMed] [Google Scholar]
  380. Trueheart J., Fink G. R. The yeast cell fusion protein FUS1 is O-glycosylated and spans the plasma membrane. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9916–9920. doi: 10.1073/pnas.86.24.9916. [DOI] [PMC free article] [PubMed] [Google Scholar]
  381. Vai M., Gatti E., Lacanà E., Popolo L., Alberghina L. Isolation and deduced amino acid sequence of the gene encoding gp115, a yeast glycophospholipid-anchored protein containing a serine-rich region. J Biol Chem. 1991 Jul 5;266(19):12242–12248. [PubMed] [Google Scholar]
  382. Valdivieso M. H., Mol P. C., Shaw J. A., Cabib E., Durán A. CAL1, a gene required for activity of chitin synthase 3 in Saccharomyces cerevisiae. J Cell Biol. 1991 Jul;114(1):101–109. doi: 10.1083/jcb.114.1.101. [DOI] [PMC free article] [PubMed] [Google Scholar]
  383. Valentín E., Herrero E., Sentandreu R. Incorporation of mannoproteins into the walls of aculeacin A-treated yeast cells. Arch Microbiol. 1986 Dec;146(3):214–220. doi: 10.1007/BF00403219. [DOI] [PubMed] [Google Scholar]
  384. Van Rinsum J., Klis F. M., van den Ende H. Cell wall glucomannoproteins of Saccharomyces cerevisiae mnn9. Yeast. 1991 Oct;7(7):717–726. doi: 10.1002/yea.320070707. [DOI] [PubMed] [Google Scholar]
  385. Vazquez de Aldana C. R., Correa J., San Segundo P., Bueno A., Nebreda A. R., Mendez E., del Rey F. Nucleotide sequence of the exo-1,3-beta-glucanase-encoding gene, EXG1, of the yeast Saccharomyces cerevisiae. Gene. 1991 Jan 15;97(2):173–182. doi: 10.1016/0378-1119(91)90049-h. [DOI] [PubMed] [Google Scholar]
  386. Venkov P. V., Hadjiolov A. A., Battaner E., Schlessinger D. Saccharomyces cerevisiae: sorbitol-dependent fragile mutants. Biochem Biophys Res Commun. 1974 Feb 4;56(3):599–604. doi: 10.1016/0006-291x(74)90646-9. [DOI] [PubMed] [Google Scholar]
  387. Villa T. G., Notario V., Villanueva J. R. Chemical and enzymic analyses of Pichia polymorpha cell walls. Can J Microbiol. 1980 Feb;26(2):169–174. doi: 10.1139/m80-025. [DOI] [PubMed] [Google Scholar]
  388. Vinh D. B., Welch M. D., Corsi A. K., Wertman K. F., Drubin D. G. Genetic evidence for functional interactions between actin noncomplementing (Anc) gene products and actin cytoskeletal proteins in Saccharomyces cerevisiae. Genetics. 1993 Oct;135(2):275–286. doi: 10.1093/genetics/135.2.275. [DOI] [PMC free article] [PubMed] [Google Scholar]
  389. Vossen J. H., Ram A. F., Klis F. M. Identification of SPT14/CWH6 as the yeast homologue of hPIG-A, a gene involved in the biosynthesis of GPI anchors. Biochim Biophys Acta. 1995 Apr 13;1243(3):549–551. doi: 10.1016/0304-4165(95)00002-s. [DOI] [PubMed] [Google Scholar]
  390. Watanabe M., Chen C. Y., Levin D. E. Saccharomyces cerevisiae PKC1 encodes a protein kinase C (PKC) homolog with a substrate specificity similar to that of mammalian PKC. J Biol Chem. 1994 Jun 17;269(24):16829–16836. [PubMed] [Google Scholar]
  391. Watari J., Takata Y., Ogawa M., Sahara H., Koshino S., Onnela M. L., Airaksinen U., Jaatinen R., Penttilä M., Keränen S. Molecular cloning and analysis of the yeast flocculation gene FLO1. Yeast. 1994 Feb;10(2):211–225. doi: 10.1002/yea.320100208. [DOI] [PubMed] [Google Scholar]
  392. Watzele G., Tanner W. Cloning of the glutamine:fructose-6-phosphate amidotransferase gene from yeast. Pheromonal regulation of its transcription. J Biol Chem. 1989 May 25;264(15):8753–8758. [PubMed] [Google Scholar]
  393. Weinstock K. G., Ballou C. E. Tunicamycin inhibition of epispore formation in Saccharomyces cerevisiae. J Bacteriol. 1987 Sep;169(9):4384–4387. doi: 10.1128/jb.169.9.4384-4387.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  394. Welch M. D., Drubin D. G. A nuclear protein with sequence similarity to proteins implicated in human acute leukemias is important for cellular morphogenesis and actin cytoskeletal function in Saccharomyces cerevisiae. Mol Biol Cell. 1994 Jun;5(6):617–632. doi: 10.1091/mbc.5.6.617. [DOI] [PMC free article] [PubMed] [Google Scholar]
  395. Wertman K. F., Drubin D. G., Botstein D. Systematic mutational analysis of the yeast ACT1 gene. Genetics. 1992 Oct;132(2):337–350. doi: 10.1093/genetics/132.2.337. [DOI] [PMC free article] [PubMed] [Google Scholar]
  396. Whelan W. L., Ballou C. E. Sporulation in D-glucosamine auxotrophs of Saccharomyces cerevisiae: meiosis with defective ascospore wall formation. J Bacteriol. 1975 Dec;124(3):1545–1557. doi: 10.1128/jb.124.3.1545-1557.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  397. Whitters E. A., Cleves A. E., McGee T. P., Skinner H. B., Bankaitis V. A. SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast. J Cell Biol. 1993 Jul;122(1):79–94. doi: 10.1083/jcb.122.1.79. [DOI] [PMC free article] [PubMed] [Google Scholar]
  398. Wittenberg C., Sugimoto K., Reed S. I. G1-specific cyclins of S. cerevisiae: cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase. Cell. 1990 Jul 27;62(2):225–237. doi: 10.1016/0092-8674(90)90361-h. [DOI] [PubMed] [Google Scholar]
  399. Yamamoto T., Hiratani T., Hirata H., Imai M., Yamaguchi H. Killer toxin from Hansenula mrakii selectively inhibits cell wall synthesis in a sensitive yeast. FEBS Lett. 1986 Mar 3;197(1-2):50–54. doi: 10.1016/0014-5793(86)80296-4. [DOI] [PubMed] [Google Scholar]
  400. Yamashita I., Fukui S. Transcriptional control of the sporulation-specific glucoamylase gene in the yeast Saccharomyces cerevisiae. Mol Cell Biol. 1985 Nov;5(11):3069–3073. doi: 10.1128/mcb.5.11.3069. [DOI] [PMC free article] [PubMed] [Google Scholar]
  401. Yamochi W., Tanaka K., Nonaka H., Maeda A., Musha T., Takai Y. Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae. J Cell Biol. 1994 Jun;125(5):1077–1093. doi: 10.1083/jcb.125.5.1077. [DOI] [PMC free article] [PubMed] [Google Scholar]
  402. Yarden O., Yanofsky C. Chitin synthase 1 plays a major role in cell wall biogenesis in Neurospora crassa. Genes Dev. 1991 Dec;5(12B):2420–2430. doi: 10.1101/gad.5.12b.2420. [DOI] [PubMed] [Google Scholar]
  403. Yonezawa N., Nishida E., Iida K., Yahara I., Sakai H. Inhibition of the interactions of cofilin, destrin, and deoxyribonuclease I with actin by phosphoinositides. J Biol Chem. 1990 May 25;265(15):8382–8386. [PubMed] [Google Scholar]
  404. Yoshida S., Ikeda E., Uno I., Mitsuzawa H. Characterization of a staurosporine- and temperature-sensitive mutant, stt1, of Saccharomyces cerevisiae: STT1 is allelic to PKC1. Mol Gen Genet. 1992 Feb;231(3):337–344. doi: 10.1007/BF00292700. [DOI] [PubMed] [Google Scholar]
  405. Yoshida S., Ohya Y., Goebl M., Nakano A., Anraku Y. A novel gene, STT4, encodes a phosphatidylinositol 4-kinase in the PKC1 protein kinase pathway of Saccharomyces cerevisiae. J Biol Chem. 1994 Jan 14;269(2):1166–1172. [PubMed] [Google Scholar]
  406. Yoshihisa T., Anraku Y. Nucleotide sequence of AMS1, the structure gene of vacuolar alpha-mannosidase of Saccharomyces cerevisiae. Biochem Biophys Res Commun. 1989 Sep 15;163(2):908–915. doi: 10.1016/0006-291x(89)92308-5. [DOI] [PubMed] [Google Scholar]
  407. Zheng Y., Bender A., Cerione R. A. Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae. J Biol Chem. 1995 Jan 13;270(2):626–630. doi: 10.1074/jbc.270.2.626. [DOI] [PubMed] [Google Scholar]
  408. Zheng Y., Cerione R., Bender A. Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3. J Biol Chem. 1994 Jan 28;269(4):2369–2372. [PubMed] [Google Scholar]
  409. Zheng Y., Hart M. J., Shinjo K., Evans T., Bender A., Cerione R. A. Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain. J Biol Chem. 1993 Nov 25;268(33):24629–24634. [PubMed] [Google Scholar]
  410. Ziman M., Preuss D., Mulholland J., O'Brien J. M., Botstein D., Johnson D. I. Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity. Mol Biol Cell. 1993 Dec;4(12):1307–1316. doi: 10.1091/mbc.4.12.1307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  411. Zlotnik H., Fernandez M. P., Bowers B., Cabib E. Saccharomyces cerevisiae mannoproteins form an external cell wall layer that determines wall porosity. J Bacteriol. 1984 Sep;159(3):1018–1026. doi: 10.1128/jb.159.3.1018-1026.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  412. de Nobel H., Lipke P. N. Is there a role for GPIs in yeast cell-wall assembly? Trends Cell Biol. 1994 Feb;4(2):42–45. doi: 10.1016/0962-8924(94)90003-5. [DOI] [PubMed] [Google Scholar]
  413. de la Fuente J. M., Alvarez A., Nombela C., Sanchez M. Flow cytometric analysis of Saccharomyces cerevisiae autolytic mutants and protoplasts. Yeast. 1992 Jan;8(1):39–45. doi: 10.1002/yea.320080104. [DOI] [PubMed] [Google Scholar]
  414. del Rey F., Santos T., García-Acha I., Nombela C. Synthesis of 1,3-beta-glucanases in Saccharomyces cerevisiae during the mitotic cycle, mating, and sporulation. J Bacteriol. 1979 Sep;139(3):924–931. doi: 10.1128/jb.139.3.924-931.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  415. del Rey F., Santos T., García-Acha I., Nombela C. Synthesis of beta-glucanases during sporulation in Saccharomyces cerevisiae: formation of a new, sporulation-specific 1,3-beta-glucanase. J Bacteriol. 1980 Aug;143(2):621–627. doi: 10.1128/jb.143.2.621-627.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  416. el-Sherbeini M., Clemas J. A. Cloning and characterization of GNS1: a Saccharomyces cerevisiae gene involved in synthesis of 1,3-beta-glucan in vitro. J Bacteriol. 1995 Jun;177(11):3227–3234. doi: 10.1128/jb.177.11.3227-3234.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  417. el-Sherbeini M., Clemas J. A. Nikkomycin Z supersensitivity of an echinocandin-resistant mutant of Saccharomyces cerevisiae. Antimicrob Agents Chemother. 1995 Jan;39(1):200–207. doi: 10.1128/aac.39.1.200. [DOI] [PMC free article] [PubMed] [Google Scholar]
  418. van Berkel M. A., Caro L. H., Montijn R. C., Klis F. M. Glucosylation of chimeric proteins in the cell wall of Saccharomyces cerevisiae. FEBS Lett. 1994 Jul 25;349(1):135–138. doi: 10.1016/0014-5793(94)00631-8. [DOI] [PubMed] [Google Scholar]
  419. van Zyl W., Huang W., Sneddon A. A., Stark M., Camier S., Werner M., Marck C., Sentenac A., Broach J. R. Inactivation of the protein phosphatase 2A regulatory subunit A results in morphological and transcriptional defects in Saccharomyces cerevisiae. Mol Cell Biol. 1992 Nov;12(11):4946–4959. doi: 10.1128/mcb.12.11.4946. [DOI] [PMC free article] [PubMed] [Google Scholar]

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