Skip to main content
Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1979;57(2):227–233.

Reconsideration of influenza A virus nomenclature: a WHO Memorandum*

PMCID: PMC2395768  PMID: 312157

Abstract

The system of nomenclature for influenza A viruses recommended by WHO in 1971 provided a basis for the designation of these viruses into types based on their nucleoprotein antigens. Influenza A viruses were further divided into subtypes based on the antigenic character of their haemagglutinin and neuraminidase components. To review the relevance to influenza virus nomenclature of new information on the antigenic and molecular characterization of influenza A viruses a meeting was held in Atlanta, GA, USA, in November 1978 under the auspices of WHO. Although the 1971 system of nomenclature has worked well, new information on relationships between haemagglutinin and neuraminidase subtypes indicates that the number of subtypes could be reduced. However, for the present, the participants in the meeting recommend that the 1971 system should still be used, without modification, at least until a further meeting is held in 1980. In the meantime, WHO wishes to encourage studies that will further define these relationships and solicits comments relevant to the proposals outlined in this Memorandum.

Full text

PDF
232

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Gerhard W. The analysis of the monoclonal immune response to influenza virus. II. The antigenicity of the viral hemagglutinin. J Exp Med. 1976 Oct 1;144(4):985–995. doi: 10.1084/jem.144.4.985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Hinshaw V. S., Bean W. J., Jr, Webster R. G., Easterday B. C. The prevalence of influenza viruses in swine and the antigenic and genetic relatedness of influenza viruses from man and swine. Virology. 1978 Jan;84(1):51–62. doi: 10.1016/0042-6822(78)90217-9. [DOI] [PubMed] [Google Scholar]
  3. Laver W. G., Webster R. G. Studies on the origin of pandemic influenza. 3. Evidence implicating duck and equine influenza viruses as possible progenitors of the Hong Kong strain of human influenza. Virology. 1973 Feb;51(2):383–391. doi: 10.1016/0042-6822(73)90437-6. [DOI] [PubMed] [Google Scholar]
  4. Nakajima K., Desselberger U., Palese P. Recent human influenza A (H1N1) viruses are closely related genetically to strains isolated in 1950. Nature. 1978 Jul 27;274(5669):334–339. doi: 10.1038/274334a0. [DOI] [PubMed] [Google Scholar]
  5. Virelizier J. L., Postlethwaite R., Schild G. C., Allison A. C. Antibody responses to antigenic determinants of influenza virus hemagglutinin. I. Thymus dependence of antibody formation and thymus independence of immunological memory. J Exp Med. 1974 Dec 1;140(6):1559–1570. doi: 10.1084/jem.140.6.1559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Zweerink H. J., Askonas B. A., Millican D., Courtneidge S. A., Skehel J. J. Cytotoxic T cells to type A influenza virus; viral hemagglutinin induces A-strain specificity while infected cells confer cross-reactive cytotoxicity. Eur J Immunol. 1977 Sep;7(9):630–635. doi: 10.1002/eji.1830070910. [DOI] [PubMed] [Google Scholar]

Articles from Bulletin of the World Health Organization are provided here courtesy of World Health Organization

RESOURCES