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Bulletin of the World Health Organization logoLink to Bulletin of the World Health Organization
. 1980;58(6):937–943.

An outbreak of type 2 dengue fever in the Seychelles, probably transmitted by Aedes albopictus (Skuse)

D Metselaar, C R Grainger, K G Oei, D G Reynolds, M Pudney, C J Leake, P M Tukei, R M D'Offay, D I H Simpson
PMCID: PMC2395999  PMID: 6971192

Abstract

Between December 1976 and September 1977 the Seychelles group of islands in the Indian Ocean was struck by an extensive epidemic of dengue fever. The peak of the epidemic was in the last week of February. Type 2 dengue virus was isolated from patients and mosquitos. Aedes albopictus was the sole vector. The clinical picture was that of classical dengue. Haemorrhagic fever and the shock syndrome were not observed.

Absenteeism from schools and offices, anamnestic questioning, and prevalence of antibodies in sera collected after the epidemic was over, indicated that approximately 75% of the population had been infected. Serological evidence was obtained of an epidemic of dengue in the islands more than 40 years earlier. This was confirmed by archival records.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Gubler D. J., Rosen L. Quantitative aspects of replication of dengue viruses in Aedes albopictus (Diptera: Culicidae) after oral and parenteral infection. J Med Entomol. 1977 Jan 31;13(4-5):469–472. doi: 10.1093/jmedent/13.4-5.469. [DOI] [PubMed] [Google Scholar]
  2. Gubler D. J., Rosen L. Variation among geographic strains of Aedes albopictus in susceptibility to infection with dengue viruses. Am J Trop Med Hyg. 1976 Mar;25(2):318–325. doi: 10.4269/ajtmh.1976.25.318. [DOI] [PubMed] [Google Scholar]
  3. Kuberski T. T., Rosen L. A simple technique for the detection of dengue antigen in mosquitoes by immunofluorescence. Am J Trop Med Hyg. 1977 May;26(3):533–537. doi: 10.4269/ajtmh.1977.26.533. [DOI] [PubMed] [Google Scholar]
  4. Kuberski T. T., Rosen L. Identification of dengue viruses using complement fixing antigen produced in mosquitoes. Am J Trop Med Hyg. 1977 May;26(3):538–543. doi: 10.4269/ajtmh.1977.26.538. [DOI] [PubMed] [Google Scholar]
  5. Rosen L., Gubler D. The use of mosquitoes to detect and propagate dengue viruses. Am J Trop Med Hyg. 1974 Nov;23(6):1153–1160. doi: 10.4269/ajtmh.1974.23.1153. [DOI] [PubMed] [Google Scholar]
  6. Sumarmo, Wulur H., Jahja E., Gubler D. J., Sutomenggolo T. S., Saroso J. S. Encephalopathy associated with dengue infection. Lancet. 1978 Feb 25;1(8061):449–450. doi: 10.1016/s0140-6736(78)91246-1. [DOI] [PubMed] [Google Scholar]
  7. Varma M. G., Pudney M., Leake C. J., Peralta P. H. Isolations in a mosquito (Aedes pseudoscutellaris) cell line (Mos. 61) of yellow fever virus strains from original field material. Intervirology. 1975;6(1):50–56. doi: 10.1159/000149453. [DOI] [PubMed] [Google Scholar]

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