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. 1991 Nov;67(793):984–987. doi: 10.1136/pgmj.67.793.984

Association of Addison's disease with autoimmune disorders--a long-term observation of 180 patients.

A A Kasperlik-Zaluska 1, B Migdalska 1, B Czarnocka 1, J Drac-Kaniewska 1, E Niegowska 1, W Czech 1
PMCID: PMC2399126  PMID: 1775423

Abstract

This study aimed at evaluating the frequency of autoimmune disorders in Addison's disease. We have observed 180 patients (113 females, 67 males, aged 9-74 years) for 1 to 26 years. Tuberculosis was noted in 54 patients. Autoimmune disorders were found in 80 patients (44%); however, 125 (69%) patients were believed to have an autoimmune origin of adrenocortical insufficiency. In 20 patients two or more autoimmune disorders were found to coexist with Addison's disease.

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Selected References

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  1. Betterle C., Peserico A., Bersani G. Vitiligo and autoimmune polyendocrine deficiencies with autoantibodies to melanin-producing cells. Arch Dermatol. 1979 Mar;115(3):364–364. [PubMed] [Google Scholar]
  2. Czarnocka B., Ruf J., Ferrand M., Carayon P., Lissitzky S. Purification of the human thyroid peroxidase and its identification as the microsomal antigen involved in autoimmune thyroid diseases. FEBS Lett. 1985 Oct 7;190(1):147–152. doi: 10.1016/0014-5793(85)80446-4. [DOI] [PubMed] [Google Scholar]
  3. GASTINEAU C. F., MYERS W. R., ARNOLD J. W., MCCONAHEY W. M. THYROID DISORDERS IN ADDISON'S DISEASE. 2. GRAVES' DISEASE. Mayo Clin Proc. 1964 Dec;39:939–944. [PubMed] [Google Scholar]
  4. GOUDIE R. B., PINKERTON P. H. Anterior hypophysitis and Hashimoto's disease in a young woman. J Pathol Bacteriol. 1962 Apr;83:584–585. [PubMed] [Google Scholar]
  5. Jeske W., Gajl-Peczalska K., Kasperlik-Zaluska A. Przeciwciała nadnerczowe w chorobie Addisona i chorobie Cushinga. Pol Arch Med Wewn. 1971 Nov;47(5):485–491. [PubMed] [Google Scholar]
  6. Jeske W., Niewiadomska A., Czerwińska A. Oznaczanie całkowitego stezenia tyroksyny i trójjodotyroniny w surowicy metoda radioimmunologiczna. Endokrynol Pol. 1977 Mar-Apr;28(2):109–115. [PubMed] [Google Scholar]
  7. Kasperlik-Załuska A., Drac-Kaniewska J., Górowski T., Czech W. Skojarzenie choroby Addisona i nadczynności tarczycy. Endokrynol Pol. 1986;37(5):231–236. [PubMed] [Google Scholar]
  8. Kasperlik-Załuska A., Górowski T., Jeske W., Kaniewski M., Bardadin K. Kliniczne znaczenie przeciwciał tarczycowych w chorobie Addisona. Pol Tyg Lek. 1978 Apr 24;33(17):671–673. [PubMed] [Google Scholar]
  9. Meyerson J., Lechuga-Gomez E. E., Bigazzi P. E., Walfish P. G. Polyglandular autoimmune syndrome: current concepts. CMAJ. 1988 Apr 1;138(7):605–612. [PMC free article] [PubMed] [Google Scholar]
  10. Midgley A. R., Jr Radioimmunoassay: a method for human chorionic gonadotropin and human luteinizing hormone. Endocrinology. 1966 Jul;79(1):10–18. doi: 10.1210/endo-79-1-10. [DOI] [PubMed] [Google Scholar]
  11. Nerup J. Addison's disease - a review of some clinical, pathological and immunological features. Dan Med Bull. 1974 Oct;21(6):201–217. [PubMed] [Google Scholar]
  12. Nerup J. Addison's disease--clinical studies. A report fo 108 cases. Acta Endocrinol (Copenh) 1974 May;76(1):127–141. doi: 10.1530/acta.0.0760127. [DOI] [PubMed] [Google Scholar]
  13. Neufeld M., Maclaren N. K., Blizzard R. M. Two types of autoimmune Addison's disease associated with different polyglandular autoimmune (PGA) syndromes. Medicine (Baltimore) 1981 Sep;60(5):355–362. doi: 10.1097/00005792-198109000-00003. [DOI] [PubMed] [Google Scholar]
  14. Pawelski S., Hartwig W., Rechowicz K., Konopka L., Kasperlik-Zaluska A. Vitamin B 12 metabolism in adrenocortical insufficiency. Haematologia (Budap) 1970;4(3):287–293. [PubMed] [Google Scholar]
  15. Pestell R. G., Best J. D., Alford F. P. Lymphocytic hypophysitis. The clinical spectrum of the disorder and evidence for an autoimmune pathogenesis. Clin Endocrinol (Oxf) 1990 Oct;33(4):457–466. [PubMed] [Google Scholar]
  16. UTIGER R. D. RADIOIMMUNOASSAY OF HUMAN PLASMA THYROTROPIN. J Clin Invest. 1965 Aug;44:1277–1286. doi: 10.1172/JCI105234. [DOI] [PMC free article] [PubMed] [Google Scholar]

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