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. 1984 Jun;47(6):1343–1345. doi: 10.1128/aem.47.6.1343-1345.1984

Selective Inhibition by 2-Bromoethanesulfonate of Methanogenesis from Acetate in a Thermophilic Anaerobic Digestor

S H Zinder 1,*, T Anguish 1, S C Cardwell 1
PMCID: PMC240241  PMID: 16346572

Abstract

The effects of 2-bromoethanesulfonate, an inhibitor of methanogenesis, on metabolism in sludge from a thermophilic (58°C) anaerobic digestor were studied. It was found from short-term experiments that 1 μmol of 2-bromoethanesulfonate per ml completely inhibited methanogenesis from 14CH3COO−, whereas 50 μmol/ml was required for complete inhibition of 14CO2 reduction. When 1 μmol of 2-bromoethanesulfonate per ml was added to actively metabolizing sludge which was then incubated for 24 h. it caused a 60% reduction in methanogenesis and a corresponding increase in acetate accumulation; at 50 μmol/ml it caused complete inhibition of methanogenesis and accumulation of acetate. H2, and ethanol.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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