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. 1991 May;65(5):2732–2735. doi: 10.1128/jvi.65.5.2732-2735.1991

Differentiation of human embryonal carcinoma cells induces human immunodeficiency virus permissiveness which is stimulated by human cytomegalovirus coinfection.

G Hirka 1, K Prakash 1, H Kawashima 1, S A Plotkin 1, P W Andrews 1, E Gönczöl 1
PMCID: PMC240639  PMID: 1850047

Abstract

Human immunodeficiency virus (HIV) replicates in differentiated but not undifferentiated NTERA-2 human embryonal carcinoma cells; neither cell type expresses CD4. Susceptibility of the differentiated cells is enhanced by coinfection with cytomegalovirus. HIV infection induces lactoseries glycolipids, suggesting a mechanism whereby HIV might interfere with normal embryogenesis.

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Selected References

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